Clinical trials
Left Main Coronary Artery Stenosis clinical trials
Below are recruiting left main coronary artery stenosis clinical trials, each written for real people, not researchers. We’re tracking 87 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06559332Recruiting
Heart artery checks during aortic valve replacement
This study tests different ways to check for blocked heart arteries in patients getting a new aortic valve through a tube in the leg. It aims to find the best approach to guide treatment.
BernAges 70 years+ - NCT07182955Recruiting
Exercise training for chest pain with clear arteries
This research study looks at why people with chest pain but clear heart arteries have low fitness. It tests whether a home-based interval training program (short bursts of hard exercise) can improve fitness and quality of life.
Charlottesville, VirginiaAges 18–85 - NCT06376630Recruiting
Esmolol for heart protection during heart attack
This study tests if giving a fast-acting heart medication (esmolol) early through an IV can protect the heart muscle during a heart attack. It may help patients who cannot receive a standard treatment due to certain risks.
MoscowAges 18 years+ - NCT07286578Recruiting
Using heart CT scans to guide treatment for blocked arteries
This trial is testing whether a special heart CT scan (coronary CT angiography) can help doctors better understand and treat calcium buildup in your heart arteries. If you have a type of heart disease that might need a stent or other procedure, this study could help decide the best approach.
Boston, MassachusettsAges 18–85 - NCT07133984Recruiting
Heart imaging study for people with heart failure and blocked arteries
This study uses heart MRIs to learn more about people who have heart failure and significant blockages in their coronary arteries. If you are planning to have bypass surgery or a stent, the study may be a fit.
Brooklyn, New YorkAges 18 years+ - NCT07009418Recruiting
CT scan vs. usual care after heart stent or balloon treatment
This trial tests whether a CT scan of the heart arteries is a safe and effective alternative to standard follow-up tests in people who have had a stent or drug-coated balloon placed in a high-risk coronary artery. It may help reduce the need for additional invasive procedures.
Bucheon-siAges 19 years+ - NCT06275399Recruiting
Study of plaque and platelets in narrowed heart arteries
This study looks at how plaque buildup and blood platelets interact in partially blocked heart arteries. It might help find better ways to treat people with chronic coronary syndrome.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06919562Recruiting
Better stent placement using imaging and newer scaffolds
This trial tests if using advanced imaging (like OCT or IVUS) to guide placement of a newer type of stent (bioresorbable scaffold) can reduce future stent problems. It is for people with stable coronary artery disease who need a stent in a main heart artery.
DordrechtAges 18 years+ - NCT07159087Enrolling by invitation
New drug balloon for re-narrowed stents
This trial tests a new drug-coated balloon (Genoss SCB) versus an existing one (SeQuent Please NEO) for people whose heart stents have re-narrowed. It aims to see which balloon better keeps the artery open.
Gyeonggi-doAges 19 years+ - NCT05807841Recruiting
AI ultrasound during stent placement in heart artery blockages
This trial tests an artificial-intelligence tool that uses a heart ultrasound to help guide stent treatment. It may help doctors choose the best way to treat blockages and improve stent results for people with symptoms from reduced blood flow to the heart.
Bucheon-siAges 19 years+ - NCT06551662Recruiting
Balloon vs. stent for split artery blockages
This trial compares two ways to open a blocked artery that splits into two branches (a bifurcation): using a balloon coated with medicine (drug-coated balloon, or DCB) versus a drug-eluting stent (DES). The goal is to see which approach works better for patients with this type of blockage.
MilanAges 18 years+ - NCT06954714Recruiting
Balloon vs stent for new heart blockages
This trial compares two treatments for new blockages in heart arteries: a drug-coated balloon (a tiny balloon that delivers medicine) versus a drug-eluting stent (a small mesh tube that releases medicine). The study hopes to see which approach keeps the artery open longer and is safer over time.
Busan, BusanAges 19 years+ - NCT06822712Recruiting
Sirolimus-coated balloon for heart artery branch blockages
This trial tests a new balloon coated with sirolimus (a drug that helps prevent re-blockage) for treating blocked arteries at branch points (bifurcations) in the heart. If you have a blocked artery at a branch point, this study may offer a way to treat the side branch without placing a stent there.
Lanzhou, GansuAges 18–80 - NCT06855537RecruitingPhase 4
Stent for vulnerable plaques in heart patients
This trial tests whether implanting stents in non-obstructive, high-risk plaques (thin-capped fatty plaques) can prevent future heart attacks. It is for people who have already had treatment for a recent heart attack or unstable angina and have additional plaques that are not severely blocking blood flow but are vulnerable.
Beijing, Beijing MunicipalityAges 18–80 - NCT05438121Recruiting
Tests a drug-coated balloon to stabilize clogged heart arteries
This trial studies whether a drug-coated balloon can better treat new, narrowed spots in multiple coronary arteries and “stabilize” the plaque. It may help improve blood flow after a procedure called balloon angioplasty for selected patients.
Ansan-si, Gyeonggi-doAges 18–85 - NCT07521007RecruitingPhase 2
YN001 treatment for coronary artery disease
This study tests whether a new drug called YN001 can help people with coronary atherosclerosis (narrowing of heart blood vessels). The trial aims to see if it can improve outcomes in people who have early-stage blockages in their heart arteries.
Huntsville, AlabamaAges 18–80 - NCT07045194Recruiting
Study of Virtue balloon for coronary stent re-narrowing
This trial tests a special balloon to treat narrowed areas inside a previously placed heart stent. It may help by reopening the artery without adding another stent.
Gainesville, FloridaAges 18 years+ - NCT07422688Enrolling by invitation
Using light scans to find heart artery blockages
This trial uses a special light-based scan (optical coherence tomography, or OCT) to help doctors see inside your heart arteries and find the exact blockage causing your heart attack. It may help guide treatment more precisely.
LeuvenAges 18 years+ - NCT07010094Recruiting
Shockwave balloons for hardened heart artery blockages
This trial tests a special balloon that uses shock waves to crack calcium in heart arteries, making it easier to place a stent. It is for people with chest pain or signs of heart strain due to a single, severely blocked artery with dense calcium.
Fujian, XiamenAges 18–85 - NCT07397845Recruiting
Stents vs drug-coated balloons for small or complex heart vessels
This trial compares two treatments—stents and paclitaxel-coated balloons—for people with narrowed heart arteries that are small, long, or complex. It aims to find which option works better to restore blood flow.
Lucerne, Canton of LucerneAges 18 years+ - NCT05865600Recruiting
PET/CT guided planning for treatment in chronic coronary disease
This trial uses a heart scan (PET/CT) to better estimate blood flow in people with long-term coronary artery disease. It aims to help doctors choose the best treatment strategy and decide who may need more invasive testing or procedures.
Herning, Central JutlandAges 18 years+ - NCT06436092Recruiting
Stent treatment for left main coronary artery disease
This trial studies a new way to treat blockages in the left main coronary artery using a drug-coated stent. It aims to find out if a careful approach with a single stent and temporary side-branch support works well for people with heart disease.
Ichinomiya, Aichi-kenAges 18 years+ - NCT05347069RecruitingPhase 4
Aspirin study for people with stable heart artery disease
This trial tests whether daily aspirin is safe and effective for people who have stable (chronic) coronary artery disease but cannot have procedures to open blocked arteries. It may help reduce future heart problems, while also checking for side effects and risks from aspirin.
KyotoAges 20 years+ - NCT07386418Recruiting
Angina thresholds study for patients needing stent treatment
This trial is testing a new way to measure blood flow in the heart during exercise to better understand angina. You may be eligible if you have at least two blocked heart arteries and are scheduled for stent placement.
BasildonAges 18 years+
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Common questions
- Are there clinical trials for left main coronary artery stenosis?
- Yes. Clin2 currently lists 87 recruiting left main coronary artery stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a left main coronary artery stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a left main coronary artery stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.