Clinical trials
Long COVID clinical trials
Below are recruiting long covid clinical trials, each written for real people, not researchers. We’re tracking 89 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05851859Recruiting
Breathing training for long COVID symptoms
This study tests whether a structured breathing control technique can improve symptoms of long COVID. It may help by training how you breathe, but you must meet specific health and medication criteria to join.
Saint-DenisAges 18 years+ - NCT06452095Recruiting
Hyperbaric oxygen therapy for long COVID brain fog
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) helps with long COVID symptoms, especially brain fog and thinking problems. It may be an option if you have had lingering symptoms for at least 2 months and can travel to one of the study sites.
Toronto, OntarioAges 18 years+ - NCT07110714Recruiting
Kneipp water therapy for post-COVID recovery
This study tests if Kneipp hydrotherapy (a gentle water therapy) can help improve symptoms in people with Post-COVID Syndrome. You will use a smartphone app to track your heart rate and answer questionnaires.
Füssen, BavariaAges 18 years+ - NCT05293366Recruiting
Long COVID study testing supportive care for multiple body systems
This study looks at people who have recovered from COVID-19 but still deal with long-term problems. It aims to better understand (and potentially help with) ongoing issues that can affect hormones, metabolism, mood, muscles, the heart, lungs, and skin.
NaplesAges 18 years+ - NCT06257420Enrolling by invitation
Low-dose rapamycin for ME/CFS and Long-COVID
This trial tests whether a low dose of rapamycin, a drug that may help regulate the immune system, can improve symptoms in people with ME/CFS or Long-COVID.
Palo Alto, CaliforniaAges 18–65 - NCT05926505RecruitingPhase 2/Phase 3
Anakinra for lingering symptoms after COVID-19
This Phase 2/3 trial studies whether anakinra can improve ongoing (post-acute) COVID-19 symptoms lasting for more than two months. It mainly looks for better safety and symptom improvement in people with specific inflammation and lung-related findings.
JenaAges 18 years+ - NCT05582512Recruiting
Study of long-term effects in children after COVID-19
This study looks at what long-term health effects children may have after getting COVID-19, and how those effects change over time. You may be asked to share health information and possibly complete a scan that can’t be done if certain metal is present.
Taipei, Chung Cheng DistrictAges Up to 18 years - NCT06876948Recruiting
Long COVID brain effects in children
This study looks at brain and nerve problems in children and teens who had COVID-19. It uses brain scans and other tests to understand long-lasting symptoms like headaches, tiredness, memory issues, or dizziness.
Pisa, PIAges 6–16 - NCT06511050RecruitingPhase 1/Phase 2
Testing Lumbrokinase for Long COVID, Lyme, and Chronic Fatigue
This trial tests a supplement called Lumbrokinase (derived from earthworms) to see if it helps reduce symptoms in people with Long COVID, post-treatment Lyme disease syndrome, or ME/CFS. It may benefit those whose daily life is significantly affected by these conditions.
New York, New YorkAges 18 years+ - NCT06441955RecruitingPhase 4
Long Covid prevention and health support trial
This trial tests a care program designed to help people who continue to have symptoms after recovering from COVID-19. It aims to prevent long-term health problems and improve well-being.
Bethesda, MarylandAges 18–65 - NCT07726082Recruiting
A group program to help with long-term fatigue
This study tests a new way to help people with long-term fatigue that gets in the way of daily life. It uses a group program that focuses on making small, helpful choices to feel better.
BaselAges 18–65 - NCT06086366Recruiting
Brain scan study for depression after COVID-19
This study uses brain scans to understand depression that starts soon after COVID-19. Researchers want to see if there are changes in brain chemistry related to depression, and you may help find new treatment targets.
Toronto, OntarioAges 18–75 - NCT07154199Recruiting
Ultrasound for brain fog after COVID-19
This trial tests if gentle ultrasound waves to the head can help clear brain fog that lasts after a COVID-19 infection. If you've had COVID and still feel mentally slow or forgetful, this treatment might help your thinking get sharper.
Beijing, Beijing MunicipalityAges 18–75 - NCT04978571Recruiting
Electrical nerve stimulation for long-lasting concussion symptoms
This study tests whether a device that delivers gentle electrical signals to nerves through the skin can help children and teens with concussion symptoms that have lasted at least 3 months. You may be asked to attend clinic visits for the nerve stimulation setup if you meet the safety and scheduling requirements.
Orange, CaliforniaAges 11–18 - NCT06928116Recruiting
Heat therapy and mobility for COVID-19 survivors
This study tests whether heat therapy (like using a heated blanket or suit) can help people who still feel tired or weak months after COVID-19. It may improve your physical function and make daily activities easier.
Omaha, NebraskaAges 50–90 - NCT05268523Recruiting
Online self-management program for long COVID symptoms
This trial tests an online self-management program to help people cope with long COVID symptoms in everyday life. It may help if you’re struggling with ongoing symptoms like mood changes, memory/thinking issues, or physical problems after COVID.
Toronto, OntarioAges 18 years+ - NCT06792214RecruitingPhase 4
Testing if antivirals prevent long-term heart problems after COVID-19
This study tests whether two antiviral medications, Paxlovid and Veklury (remdesivir), can reduce the risk of long-term heart and blood vessel problems after a COVID-19 infection. It is for adults recently hospitalized with COVID-19 who are not currently on oxygen therapy.
Kingston, OntarioAges 18 years+ - NCT05610436Recruiting
Long COVID patients: tracking symptoms and outcomes over time
This study follows people who have ongoing symptoms after COVID (“post-Covid condition”) to better understand how symptoms change and what factors affect recovery. It may help improve care for patients seen at a Long COVID support clinic.
Vandœuvre-lès-Nancy, Grand EstAges 18 years+ - NCT06590324RecruitingPhase 2/Phase 3
Study of Apabetalone for long COVID
This trial tests an experimental drug called Apabetalone for people with long COVID. You may be eligible if you have type 2 diabetes, take or are willing to take dapagliflozin, and have had long COVID symptoms for at least 2 months after your COVID infection.
AmmanAges 18 years+ - NCT07567274Enrolling by invitationPhase 2
DMSO Therapy for Ringing in Ears After COVID
This trial tests a combination therapy using DMSO (a chemical that penetrates tissues) mixed with several medications to treat persistent ringing in the ears (tinnitus) that developed or worsened after COVID-19 infection or vaccination. If you have bothersome tinnitus linked to long COVID or vaccine injury and haven't responded to previous treatments, this study may help.
Ithaca, New YorkAges 18–70 - NCT07189936RecruitingPhase 2
Testing 2-HOBA for Immune Issues in Long COVID with POTS
This trial tests if a medication called 2-HOBA can help with ongoing immune system issues in people with Long COVID who also have POTS. It aims to reduce fatigue and other symptoms by calming overactive immune responses.
Nashville, TennesseeAges 18 years+ - NCT04736732Recruiting
Post-COVID research clinic for adults in Quebec
This study invites adults in Quebec to complete questionnaires and possibly follow-up checks about past COVID-19 infection or symptoms. It may help researchers better understand ongoing effects after COVID, or compare people with different COVID test histories.
Montreal, QuebecAges 18–100 - NCT05894616Recruiting
Home monitoring study for lasting breathing symptoms after COVID
This study looks at people with lingering post-COVID symptoms, especially breathing and lung-related findings, using home monitoring and medical tests. It may help researchers understand what’s driving ongoing symptoms and identify patterns that could guide better care.
Stockholm, SverigeAges 18–50 - NCT06920628RecruitingPhase 1
Brain scan study for long COVID neurological symptoms
This study uses a special PET scan to look at brain inflammation in people with neurological symptoms after COVID-19. It aims to understand how inflammation might be linked to ongoing problems like brain fog or memory issues.
Bethesda, MarylandAges 18–70
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Common questions
- Are there clinical trials for long covid?
- Yes. Clin2 currently lists 89 recruiting long covid studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a long covid trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a long covid trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.