Clinical trials
Lumbar Disc Herniation clinical trials
Below are recruiting lumbar disc herniation clinical trials, each written for real people, not researchers. We’re tracking 56 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07413302Recruiting
Predicting recovery after back surgery for leg weakness
This study looks at which factors before surgery help predict how well leg weakness improves after a single-level microdiskectomy (minimally invasive back surgery for a slipped disk). It may help you understand what to expect if you are having this procedure.
KavalaAges 18 years+ - NCT07418944Recruiting
Surgery vs. non-surgery for leg pain from a slipped disc
This trial compares surgery to non-surgical treatments for people with leg pain caused by a lumbar disc herniation (slipped disc). It tests if surgery provides better relief after at least 6 weeks of symptoms.
HelsinkiAges 18–60 - NCT07674407Recruiting
Fear of movement and physical function in back pain
This study looks at how fear of movement relates to physical function in people with long-term low back pain from a herniated disc. It may help understand how to improve daily activities.
IstanbulAges 18–65 - NCT07489001Recruiting
Comparing opioid-free to standard anesthesia for back surgery
This study compares two types of anesthesia for lower back surgery: one that uses opioids and one that does not. The goal is to see which approach controls pain better with fewer side effects.
Istanbul, MaltepeAges 18–75 - NCT07204197Enrolling by invitation
Virtual Reality Physical Therapy After Lumbar Disc Surgery
This study tests whether using virtual reality (VR) during physical therapy after lumbar disc surgery helps you recover better in the first few days. You'll do standard exercises with or without VR games to see if it improves your movement and pain.
Ankara, AnkaraAges 18–65 - NCT07060235Enrolling by invitation
Mobile app for disc herniation recovery
This trial tests a mobile app that guides you through exercises for disc herniation. The app is designed to help strengthen the muscles that support your spine and may reduce pain.
AnkaraAges 20–55 - NCT06534593Enrolling by invitation
Physical therapy for low back pain from disc herniation
This trial tests whether physical therapy can help people with a specific type of disc herniation (postero-lateral) by improving pain, stability, walking, and daily function. It may be a good fit if you have low back pain that spreads to your leg or stays in your back.
Islamabad, FederalAges 18–50 - NCT05444751Enrolling by invitationPhase 3
Different pain medicine plans for back surgery
This Phase 3 study compares two combinations of anesthesia and pain medications during lumbar decompression surgery, to see which helps more. It may help patients by aiming for better pain control and recovery using one planned medication approach.
New York, New YorkAges 18–80 - NCT05033457Enrolling by invitation
Compare two treatments for lumbar spinal canal narrowing
This trial compares two approaches (UBE and PETD) for relieving nerve pressure caused by a single-level problem in the lower spine. It may help reduce pain and nerve symptoms by treating the narrowed spinal canal or disc-related compression.
Taiyuan, ShanxiAges Any age - NCT06462729RecruitingPhase 1/Phase 2
Testing a new bone graft for lower back fusion surgery
This trial tests a new bone graft material called LDGraft for people who need a single-level lower back fusion (anterior lumbar interbody fusion). It aims to see if the new graft is as good as or better than current options for helping bones heal together.
Fort Wayne, IndianaAges 22–80 - NCT07763522Enrolling by invitation
Measuring ankle strength in people with herniated disc weakness
This study tests a new way to measure ankle strength in people who have weakness from a herniated disc in the lower back. The goal is to confirm the measurement tool works well for tracking such weakness.
Helsinki, UusimaaAges 18–65 - NCT07515287Enrolling by invitation
Pilates for Back Pain Recovery in Middle-Aged Women
This study tests whether Pilates exercises can help women aged 45–60 with chronic lower back disc problems improve their balance, leg strength, and body awareness. Pilates focuses on core stability and controlled movement, which may help restore function lost due to the disc herniation.
Kahramanmaraş, onikişubatAges 45–60 - NCT04182997RecruitingPhase 4
Epidural steroid shot during discectomy for back nerve pain
This trial studies whether giving a steroid medicine into the epidural space during discectomy (back surgery for a herniated disc) helps reduce nerve pain and symptoms. It is mainly for people whose MRI and exam show a single-level lumbar disc herniation after non-surgical treatments didn’t help.
Columbia, MissouriAges 18 years+ - NCT05963815Recruiting
Spine surgery follow-up using online patient-reported questionnaires
This study looks at recovery after planned (elective) surgery for common lower-back (“lumbar”) spine problems like slipped discs, disc bulges, and narrowing of the spinal canal. You may be asked to complete online questionnaires, and the study uses your answers to understand symptoms and outcomes after surgery.
Rotterdam, South HollandAges 18–80 - NCT06469905Recruiting
Nerve block for pain from herniated disc
This study tests a nerve block injection (called an erector spinae plane block) to see if it helps reduce pain from a herniated disc in the lower back. It may be a good fit if you have ongoing low back pain and have not had spine surgery before.
ElâzığAges 18–65 - NCT06853132Recruiting
Baduanjin with resistance training for back pain or osteoporosis
This study tests a gentle exercise program called Baduanjin combined with resistance training for people with back problems or osteoporosis who are about to have surgery. It aims to see if this type of exercise helps before and after the procedure.
Changsha, HunanAges 45 years+ - NCT06933498Recruiting
Nerve block for less pain meds in back surgery
This trial tests whether a nerve block (called an erector spinae plane block) given before surgery can reduce the amount of pain medicine and anesthesia needed during lumbar disc surgery. It may help people have less pain and fewer side effects.
AnkaraAges 18–75 - NCT06143813Recruiting
Precision treatment for lumbar nerve pain with targeted block
This trial tests if a targeted nerve root injection can improve outcomes for people with persistent leg pain from a compressed nerve in the lower back, with the goal of tailoring surgery more precisely.
Aarhus CAges 18 years+ - NCT07036445Recruiting
PRP vs steroids for leg pain from a slipped disc
This study compares two treatments—platelet-rich plasma (PRP) and steroids—given as an injection into the spine for leg pain caused by a herniated disc. It's for people who haven't improved after 6 weeks of standard care.
MérignacAges 18 years+ - NCT07044206Recruiting
Comparing two bone graft materials for lumbar fusion surgery
This trial compares two types of bone graft materials (Magnetos Putty and GlassBone Putty) used in lower back fusion surgery for adults with degenerative disc disease. The goal is to see which material works better for helping the bones fuse together, which may reduce pain and improve function.
Montpellier, FranceAges 18–80 - NCT05745129Enrolling by invitation
AI tool for personalized care decisions in spine problems
This trial looks at using an artificial intelligence (AI) tool to help guide care choices for people with spine problems. It may help doctors assess whether you need surgery or a different approach, especially when disc herniation isn’t the main issue.
Oslo, NorgeAges 18–80 - NCT07222787Recruiting
Testing a new spinal implant for lower back fusion
This trial tests a new spinal implant system (CORUS-LX) for fusing two lower back discs that are causing pain. It is meant for people with severe, long-lasting back or leg pain that hasn't improved with non-surgical treatments.
Scottsdale, ArizonaAges 18–80 - NCT07722117Recruiting
Reiki for pain after back surgery
This trial tests if Reiki, a gentle hands-on energy therapy, can help reduce pain after lumbar (lower back) surgery. It may offer a drug-free option to help you feel better during recovery.
ParisAges 18 years+ - NCT06704919Recruiting
Spinal fusion using conduit cages and bone graft putty
This trial tests a new combination of a cage and bone graft putty for spinal fusion surgery. It is for people with degenerative disc disease or a herniated disc in the neck or lower back that needs surgery.
Pittsburgh, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for lumbar disc herniation?
- Yes. Clin2 currently lists 56 recruiting lumbar disc herniation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lumbar disc herniation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lumbar disc herniation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.