Lumbar Fusion Surgery clinical trials

Long-term results after surgery for lumbar spinal stenosis

This study looks at patients who had back surgery for lumbar spinal stenosis and a condition called spondylolisthesis between 2007 and 2015. They want to see how many people needed another operation years later.

Rehab pathway vs usual care after lumbar spine surgery

This trial compares a new rehab program called R3 (which includes pre-surgery preparation and post-surgery recovery support) with standard care for people having lumbar spine surgery. It aims to see if the R3 pathway helps you recover better and return to work faster.

Comparing fusion surgery to rehab for chronic low back pain

This trial compares two approaches for chronic low back pain caused by worn discs: lumbar fusion surgery versus a structured multidisciplinary rehabilitation program. It aims to see which treatment provides better long-term relief and function.

Reduce adjacent back pain after lumbar surgery

This trial looks at whether a limited decompression (a careful nerve-space “freeing” procedure) can help prevent future problems in the spinal level next to your planned surgery. It targets people with spinal canal narrowing next to the surgery level but who do not yet have symptoms there.

A new surgery for lumbar disc disease without fusion

This trial tests a surgical technique that treats a damaged disc in your lower back without permanently fusing the bones together. It may be an option if you have had at least 3 months of other treatments like physical therapy or medication and they have not helped enough.

A new cage for spinal fusion surgery

This trial is testing a new device called the CONDUIT cage for a type of back surgery called anterior lumbar interbody fusion (ALIF). The surgery helps treat degenerative disc disease in the lower back by fusing two vertebrae together using a cage to support the spine. The study will see how well this cage works in patients who are already scheduled for this surgery.

Novosis Putty for spine fusion in lumbar disc disease

This trial tests a new bone graft putty (Novosis Putty) used during a specific type of spine fusion surgery (TLIF) to treat a worn-out disc causing low back and leg pain. The goal is to see if it works as well as or better than current options.

Ear Stimulation After Back Surgery

This study tests whether a gentle electrical stimulation placed on the ear (tAuricular Neurostimulation) can help reduce pain and improve recovery after lumbar spine surgery. It is for people who are already scheduled for a lumbar fusion or laminectomy and want to see if this non-invasive approach can ease their post-surgery discomfort.

Testing a new bone graft for lower back fusion surgery

This trial tests a new bone graft material called LDGraft for people who need a single-level lower back fusion (anterior lumbar interbody fusion). It aims to see if the new graft is as good as or better than current options for helping bones heal together.

Dexamethasone before spine surgery for pain control

This study tests whether giving a single dose of the steroid dexamethasone before minimally invasive spine surgery can help reduce pain and inflammation afterward. It is for people aged 50–80 who are having surgery on 1 or 2 levels of their lower back and have not had spine surgery before.

Test bone putty for back fusion versus bone graft alternatives

This study compares a ready-to-use bone putty to standard bone graft materials (with or without your own bone) during back fusion surgery for unstable lower back problems. It looks at whether the putty works as well or better to help the bones fuse and heal.

Rehabilitation With Empowered STrategies to Optimize REcovery

Retrolaminar block for lumbar fusion with multimodal pain control

This study tests whether adding a retrolaminar block (a type of back injection) to standard pain medicines helps reduce pain after lumbar spine fusion surgery. It may help you recover with less need for strong painkillers.

Exercise program for frail older adults after back fusion surgery

This trial tests whether a special exercise program after lower back fusion surgery can help prevent complications in older adults who are frail. If you are 75 or older and having your first small back fusion, this rehab might help you recover better.

Massage therapy after upper or lower back surgery

This study tests if massage therapy can help children recover after their first back surgery (thoracic or lumbar fusion). It's for kids who can talk and don't have certain health problems like chronic pain or bleeding disorders.

Two surgical approaches for lumbar spine narrowing

This trial compares two slightly different surgical techniques for treating lumbar spinal stenosis (a narrowing of the spinal canal that causes leg pain). Both procedures fuse one level of your spine to relieve pain, but use slightly different approaches through the side of the spine.

Iron therapy before back surgery for elderly with anemia

This trial tests whether giving iron before multi-level lumbar fusion surgery helps improve anemia in older adults. It could be an option if you are 65 or older, have anemia, and are scheduled for this type of back surgery.

Online therapy for back pain and recovery after spinal fusion

This trial tests if internet-based cognitive behavioral therapy can help people recover better after lumbar fusion surgery by reducing pain, strengthening back muscles, and improving outlook on recovery. You can participate from home using WiFi.

OssiMend bone graft for lumbar spine fusion surgery

This trial studies whether OssiMend bone graft helps heal a lumbar spine fusion for people whose disc disease has not improved with non-surgical care. It may be an option if you need back surgery due to specific spine wear-and-tear changes.

INFUSE bone graft for lower back fusion: patient follow-up study

This study tracks patients who receive INFUSE bone graft during a specific type of lower back fusion surgery. It helps confirm how the device performs in real-world care and monitors safety and outcomes after surgery.

New bone graft for lower back fusion surgery

This trial studies a new bone graft material called Virtuos for use in lower back spinal fusion surgery. It may help patients needing a one or two-level lumbar fusion by providing a safe and effective option for bone healing.

Nerve monitoring during a low-back fusion surgery

This study tests whether special nerve monitoring during a low-back fusion helps make surgery safer and the results easier to judge. It’s for people having a specific type of low-back fusion on one or two levels.

Testing a new spinal implant for degenerative disc disease

This trial studies a new spinal implant system (Hexanium TLIF) for people with degenerative disc disease. It aims to see if the implant is safe and works well to help with back pain and stability.

Comparing two medicines added to a nerve block for back surgery

This study compares two medicines (dexamethasone and dexmedetomidine) added to a nerve block for pain control during and after lower back surgery. It aims to see which one works better for reducing pain and the need for other painkillers.