Lumbar Spinal Fusion clinical trials

Study of Correlation Between the Level of Intradiscal Periostin Expression and Pfirrmann Grading.

Back to Life: early rehab after spinal fusion surgery

This trial tests an early rehabilitation program for people having lumbar spinal fusion surgery to see if it helps them get back to daily life faster. It may be a good option if you live in Copenhagen or Frederiksberg and have had low back pain for more than three months.

Erector spinae pain-block during lumbar fusion surgery

This study tests whether a numbing pain-block in a specific back muscle area (called an “erector spinae plane block”) can improve comfort during lumbar spinal fusion surgery. You might be eligible if you need this type of back surgery and can safely receive the numbing medicine.

Ketorolac for pain after lower back fusion surgery

This trial tests if a non-steroidal anti-inflammatory drug (NSAID) called ketorolac can help reduce pain after lower back fusion surgery. It is for people who are having elective surgery to fuse one or two bones in their lower back.

Betadine under skin during back fusion surgery

This study tests whether a small amount of Betadine placed under the skin during back fusion surgery can help prevent infection. It's for people having their first posterior spinal fusion.

Lumbar fusion outcomes with arthritis in nearby spine segments

This study looks at how well lumbar fusion surgery works long-term when the joint just above or below (adjacent segment) already shows wear-and-tear. It may help predict who benefits most and guide treatment planning.

Reduce adjacent back pain after lumbar surgery

This trial looks at whether a limited decompression (a careful nerve-space “freeing” procedure) can help prevent future problems in the spinal level next to your planned surgery. It targets people with spinal canal narrowing next to the surgery level but who do not yet have symptoms there.

Testing whether one-level fusion is needed after lumbar decompression

This trial compares outcomes after decompression surgery for one affected area in the lower back, with and without adding spinal fusion. It may help patients avoid unnecessary extra surgery—or ensure fusion is used when it’s needed.

Personalized pain relief after back fusion surgery

This trial tests a personalized plan to manage pain after lumbar (lower back) fusion and decompression surgery. It may help reduce difficult pain while guiding safe use of opioids around the time of surgery.

Nerve blocks to reduce bleeding and pain after spine surgery

This study compares two types of nerve blocks (numbing injections) given during lumbar spine fusion surgery to see which better reduces bleeding and pain after the operation. If you're having spine surgery, this trial might help your recovery be smoother with less pain and bleeding.

Spinal Fusion Recovery in Older Adults

This study is looking at how older adults recover after spinal fusion surgery, a type of back surgery that connects bones in the spine. The goal is to find factors that help people heal faster and feel better afterward.

Numbing medicine during back surgery to reduce pain

This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.

Safety and effectiveness study of spinal implants and bone materials

This study tracks how well spinal implants (Titania systems) and bone-filling materials (BONEGRAFT) work after surgery and whether patients experience any problems. Researchers will follow patients after cervical or lower spine surgery to confirm these devices are safe and effective in real-world use.

NMP fibers for spine fusion surgery

This study tests a new material called NMP fibers used during spine fusion surgery to treat conditions like degenerative disc disease, spinal stenosis, or spondylolisthesis. The goal is to see how well it works for patients having fusion in the neck or lower back.

INFUSE bone graft for lower back fusion: patient follow-up study

This study tracks patients who receive INFUSE bone graft during a specific type of lower back fusion surgery. It helps confirm how the device performs in real-world care and monitors safety and outcomes after surgery.

Two surgical approaches for lumbar spine narrowing

This trial compares two slightly different surgical techniques for treating lumbar spinal stenosis (a narrowing of the spinal canal that causes leg pain). Both procedures fuse one level of your spine to relieve pain, but use slightly different approaches through the side of the spine.

Testing a new spinal implant for lower back fusion

This trial tests a new spinal implant system (CORUS-LX) for fusing two lower back discs that are causing pain. It is meant for people with severe, long-lasting back or leg pain that hasn't improved with non-surgical treatments.

Nerve blocks to improve pain control after spinal fusion

This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.

Numbing injection for pain relief after back fusion surgery

This study tests whether a special numbing injection (called an erector spinae plane block) given near the spine during surgery can reduce pain after lumbar fusion. If you qualify, you might have less pain and need fewer painkillers after your operation.

OssiMend bone graft for lumbar spine fusion surgery

This trial studies whether OssiMend bone graft helps heal a lumbar spine fusion for people whose disc disease has not improved with non-surgical care. It may be an option if you need back surgery due to specific spine wear-and-tear changes.

Comparing bone grafts for lower back fusion surgery

This study tests if a special bone graft material (Allosync Expand) plus your own bone is as good as using just your own bone for spinal fusion surgery. It might help people with back or leg pain caused by a slipped vertebra and narrowed spine.

Test a new implant for low back pain with mild narrowing

This trial studies a new spine implant placed between the bones to help relieve low back pain. You may be a candidate if imaging shows mild-to-moderate spinal narrowing and you’ve already tried non-surgical treatments for at least 3 months.

Comparing two types of spine surgery for disc-related low back pain

This study compares two different surgery methods (Mini-TLIF and MIDLIF) for treating low back pain caused by worn-out discs in the lower back. The goal is to see which one offers better recovery, fewer complications, and lower costs.

Study of the Minuteman device for spine fusion

This study looks at how well the Minuteman device works for people with chronic low back pain and leg symptoms caused by aging spine conditions. It tests if the device helps patients move better after surgery.