Clinical trials
Lung cancer clinical trials
Cancer that begins in the lungs, often linked to smoking but also affecting non-smokers. We’re tracking 2,007 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03225586Recruiting
Study of health differences in urban and rural communities
This study enrolls consenting adults to understand how health differs between people living in cities versus rural areas. Your participation may help researchers learn what factors influence health over time.
Rosario, Santa Fe ProvinceAges 35–70 - NCT07519655RecruitingPhase 1
New Cancer Drug Treatment for Advanced Lung, Esophageal, or Skin Cancer
This study tests a new drug called PF-08046033 in people with advanced lung cancer (NSCLC), esophageal cancer (ESCC), or melanoma (skin cancer) that has spread or can't be surgically removed. The drug targets a specific protein to help slow or stop cancer growth.
Denver, ColoradoAges 18 years+ - NCT07454642RecruitingPhase 1
Study of a new drug for advanced solid tumors
This trial tests a new drug called AVA6103 for people with certain advanced solid tumors that have not responded to standard treatments. The drug may help by targeting a protein on cancer cells and interfering with their ability to multiply.
Scottsdale, ArizonaAges 18 years+ - NCT07006727RecruitingPhase 1
Study of a new drug for advanced DLL3-positive solid tumors
This trial tests an experimental treatment for several types of advanced cancer that have stopped responding to standard therapy. The drug targets a protein called DLL3 found on some tumor cells, which may help slow or stop tumor growth.
Iowa City, IowaAges 18–100 - NCT07664579Recruiting
Couples coping together against cancer support program
This trial tests a supportive care program for couples facing cancer. It helps you and your partner work together to manage the challenges of a cancer diagnosis.
Duarte, CaliforniaAges 18 years+ - NCT07046923RecruitingPhase 1
A study of LY4175408 for advanced cancer
This trial tests a new targeted drug (LY4175408) for people with certain advanced solid tumors (lung, endometrial, or triple negative breast cancer) who have already tried standard treatments. The goal is to see if the drug is safe and effective.
Stanford, CaliforniaAges 18 years+ - NCT05427136Recruiting
Study early lung problems after childhood cancer treatment
This study looks for early lung (breathing) problems in children after certain cancer treatments, using lung tests and sometimes MRI scans. It may help doctors spot breathing complications earlier and guide better care.
BaselAges 4–22 - NCT05940532RecruitingPhase 2
Sutimab plus chemotherapy for advanced lung cancer needing radiation
This trial tests a cancer-fighting antibody (sugemalimab) added to standard chemotherapy for stage III lung cancer that can’t be removed by surgery but may be treated with radiation. It aims to improve control of your cancer while checking safety and side effects.
ChangshaAges 18–75 - NCT06899789Recruiting
Long-term follow-up of colitis from checkpoint inhibitors
This study follows people who developed colitis (inflammation in the colon) after receiving immune checkpoint inhibitors for cancer. Researchers want to learn about long-term effects and outcomes.
Pavia, PaviaAges 18 years+ - NCT07217171RecruitingPhase 1
Study of EVOLVE104 for advanced bladder and squamous cell cancers
This trial tests an experimental drug called EVOLVE104 for people with advanced bladder cancer or certain types of squamous cell cancers. It aims to see if the drug is safe and if it can help shrink tumors.
Duarte, CaliforniaAges 18 years+ - NCT06945120Recruiting
Lung Health Program for Chinese and Korean Smokers
This study is testing a program to help Chinese and Korean adults who smoke to improve their lung health. You may be able to join if you are a current smoker, speak Korean, Mandarin, or English, and live in the U.S.
Boston, MassachusettsAges 18–100 - NCT07291414Recruiting
Tracking cancer medication safety with a self-monitoring platform
This trial tests a platform where you can track your experiences and concerns about cancer medications. It aims to help you and your care team manage medication safety.
Ann Arbor, MichiganAges 18 years+ - NCT07173348Recruiting
Hypnosis for managing severe breathlessness
This study tests whether hypnosis sessions can help you feel more in control of your breathlessness. If you have a chronic lung or heart condition and struggle with shortness of breath, you may be able to join a series of 3 hypnosis visits to see if it improves your daily life.
Geneva, Canton of GenevaAges 18 years+ - NCT07705178Recruiting
MRI study of heart and lung health after childhood cancer
This study uses MRI scans to look at the heart and lungs of childhood cancer survivors to see if chemotherapy caused any long-term changes. It may help doctors better understand and manage late effects after treatment for leukemia or lymphoma.
ErlangenAges 3 years+ - NCT07186699Recruiting
Lung and esophageal cancer care study for people with alcohol or substance use history
This study talks with people who have been treated for lung or esophageal cancer and have a history of alcohol or substance use. The goal is to learn about their experiences to improve cancer care and support.
Los Angeles, CaliforniaAges 18 years+ - NCT07071103RecruitingPhase 2
Low-dose radiation and immunotherapy for resistant solid tumors
This trial tests a combination of low-dose radiation to the intestines and immunotherapy for people whose cancer has stopped responding to standard treatments including immunotherapy. It may offer a new option when other therapies have failed.
Shantou, GuangdongAges 18–80 - NCT04291755Enrolling by invitation
Stool bank for people receiving cancer immunotherapy
This study is building a “stool bank,” meaning they collect and store stool samples from people who are getting cancer immunotherapy. Researchers plan to analyze these samples to better understand cancer and treatment—your participation may help future research.
Fountain Valley, CaliforniaAges 18 years+ - NCT05672108RecruitingPhase 2
Chemo delivered into lung tumors using a catheter
This trial studies a treatment that delivers chemotherapy directly to lung tumors by placing a catheter into lung blood vessels. It may help people with lung cancer or lung metastases that are growing despite standard treatment, or who cannot tolerate it.
Duarte, CaliforniaAges 18 years+ - NCT04644952Recruiting
Study of robotic lung segment surgery outcomes
This study looks at people who had a lung surgery called a segmentectomy with robotic assistance in the past. It aims to understand how these surgeries are done over time and what outcomes result for patients.
Houston, TexasAges Any age - NCT05354570RecruitingPhase 2
Radiation for thymic cancer that has spread to lung lining
This Phase 2 study tests a precise type of chest radiation that targets cancer in the lung lining (pleura) while trying to protect healthy lungs and organs. It may help people with thymic cancer that has spread to the pleura, including cases that return after prior treatment.
Basking Ridge, New JerseyAges 18–79 - NCT06472388RecruitingPhase 2
Testing two doses of everolimus for neuroendocrine tumors
This trial compares two daily doses (5 mg vs 10 mg) of everolimus, a targeted therapy, to see which works better and is safer for people with advanced neuroendocrine tumors (NETs). You may qualify if your cancer has grown despite previous treatment and you are in relatively good health.
São Paulo, São PauloAges 16 years+ - NCT07407933RecruitingPhase 1/Phase 2
YL201 with other cancer drugs for advanced solid tumors
This trial tests a new drug, YL201, combined with other cancer treatments for people with a certain type of advanced lung cancer (extensive-stage small cell lung cancer). It may help shrink tumors or slow their growth.
Washington D.C., District of ColumbiaAges 18 years+ - NCT04893785RecruitingPhase 2
Cabozantinib plus temozolomide for advanced neuroendocrine lung tumors
This Phase 2 study tests whether combining cabozantinib with temozolomide can control advanced lung or gastrointestinal neuroendocrine tumors that have grown after prior treatments. It also closely monitors safety, including blood counts, organ function, and other side effects.
Naples, CampaniaAges 18 years+ - NCT07741435Recruiting
Simple blood, urine, and saliva test to find cancer early
This study tests a new way to find cancer by looking at DNA in blood, urine, and saliva. It may help detect cancer earlier and monitor how well treatment works.
Bogotá, Bogota D.C.Ages 18 years+
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Common questions
- Are there clinical trials for lung cancer?
- Yes. Clin2 currently lists 2,007 recruiting lung cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.