Clinical trials
Lymph Node Metastases clinical trials
Below are recruiting lymph node metastases clinical trials, each written for real people, not researchers. We’re tracking 66 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06091423RecruitingPhase 2
XELOX plus fruquintinib and sintilimab for stomach cancer with liver or lymph node spread
This trial tests a combination of chemotherapy (XELOX), a targeted therapy (fruquintinib), and an immunotherapy (sintilimab) to shrink stomach cancer that has spread only to the liver or retroperitoneal lymph nodes. The goal is to make the cancer removable by surgery.
NanjinAges 18–75 - NCT06321653Recruiting
Lymphedema after radiation for early breast cancer with 1-2 positive nodes
This trial aims to see if a shorter course of radiation after breast-conserving surgery affects arm swelling (lymphedema) in people with early breast cancer that has spread to 1 or 2 nearby lymph nodes. The goal is to learn if this approach is safe and effective.
MilanAges 18 years+ - NCT07746258Recruiting
Checking if skin cancer has spread to nearby lymph nodes
This study uses a test to see if a type of skin cancer called high-risk cutaneous squamous cell carcinoma has spread to lymph nodes. The goal is to learn more about how to detect spread early, which could help guide treatment decisions.
Badalona, BarcelonaAges 18 years+ - NCT07653503RecruitingPhase 1
Lymph node immunotherapy before cervical cancer surgery
This trial tests whether giving an immunotherapy drug (nivolumab) directly into lymph nodes before standard surgery can help treat cervical cancer. It is for patients who have not had prior immunotherapy treatments.
GroningenAges 18 years+ - NCT07621614RecruitingPhase 2
Safe Surgery Guidance for Childhood Melanoma Using Genetics
This study helps doctors decide the safest surgical approach for melanoma and similar skin tumors in children and young adults by using pathology reports and genetic information. The goal is to avoid unnecessary surgery while ensuring the best outcomes.
Oakland, CaliforniaAges Up to 25 years - NCT07622836Recruiting
Chemotherapy plus QL1706 for high-risk triple-negative breast cancer
This study tests whether adding a new immunotherapy drug called QL1706 to standard chemotherapy after surgery can help patients with aggressive triple-negative breast cancer that has spread to lymph nodes. The goal is to see if this combination prevents cancer from coming back.
Nanjing, JiangsuAges 18–75 - NCT07483034Enrolling by invitation
Music therapy for anxiety during breast cancer treatment
This study tests whether listening to specially chosen music while you're in the hospital for breast cancer treatment can help lower anxiety and depression. It also looks at how music might affect certain substances in your blood that are linked to stress and healing.
Zagreb, City of ZagrebAges 18–65 - NCT04852588Recruiting
Sample chest lymph nodes during treatment for advanced lung cancer
This study checks lymph nodes in the chest (using a camera-guided test) in people with advanced non-small cell lung cancer who are getting curative-intent radiation. The trial may help doctors better confirm how far the cancer has spread and guide the best radiation treatment plan.
London, OntarioAges 18 years+ - NCT07061704RecruitingPhase 1/Phase 2
Oncolytic virus trial for esophageal cancer
This trial tests a virus-based therapy for locally advanced esophageal squamous cell carcinoma. It aims to see if the virus can target and kill cancer cells while sparing healthy tissue.
Chengdu, SichuanAges 18–80 - NCT06554652RecruitingPhase 3
Comparing two neck surgeries for thyroid cancer spread
This trial compares two types of neck surgery for people with papillary thyroid cancer that has spread to a small number of lymph nodes in the neck. The goal is to see if a less extensive lymph node removal works just as well as the standard more extensive surgery.
ShanghaiAges 14–80 - NCT06144736RecruitingPhase 2
Surgery for stage 2 seminoma testicular cancer trial
This trial is testing whether removing affected lymph nodes with surgery (RPLND) works well alone for seminoma testicular cancer that has spread to nearby nodes but is still relatively small. It is for patients who have not had extensive chemo or radiation.
DüsseldorfAges 18–99 - NCT04858880Recruiting
Personalized radiation for PSA rise after prostate surgery
This study tests a tailored (personalized) radiation plan for men whose PSA (“prostate blood test”) rises after prostate surgery but who have no detectable spread on scans. It may help control cancer growth by targeting the right area based on your situation.
JönköpingAges 18 years+ - NCT06353906RecruitingPhase 2
Chemo plus immunotherapy for advanced penile cancer
This trial tests a combination of two chemotherapy drugs (carboplatin and paclitaxel) plus the immunotherapy drug pembrolizumab (Keytruda) for penile cancer that has spread to nearby lymph nodes. The goal is to see if this combination can shrink or control the cancer before or after surgery.
LeuvenAges 18 years+ - NCT00280202Recruiting
Find lung cancer genetic markers from tissue samples
This study looks for specific genetic markers of lung cancer by testing tissue taken from a lung mass. It may help doctors detect and better understand lung cancer based on genetic clues.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05319015RecruitingPhase 2
Combination drug therapy before surgery for kidney cancer with vena cava clot
This trial tests two drugs, lenvatinib and pembrolizumab, given before surgery to shrink kidney cancer that has spread into the large vein carrying blood to the heart (the vena cava). The goal is to see if this approach makes surgery more effective and improves outcomes.
Dallas, TexasAges 18 years+ - NCT02743832Recruiting
Personalized surgery planning for early mouth cancer
This study helps doctors plan surgery more individually for early-stage oral (mouth) squamous cell carcinoma. It focuses on using tumor features found during evaluation to guide surgical decisions, aiming to improve treatment accuracy.
Guangzhou, GuangdongAges 20–70 - NCT06161818RecruitingPhase 2
Combined therapy before surgery for lymph node-positive esophageal cancer
This trial is testing a combination of chemotherapy and radiation (called total neoadjuvant therapy) before surgery for a type of esophageal cancer that has spread to lymph nodes. The goal is to see if this approach improves outcomes.
Eindhoven, North BrabantAges 18 years+ - NCT07469267Recruiting
Armpit radiation vs more surgery for early breast cancer with node spread
This trial tests whether radiation to the lower armpit (level I-II axilla) works as well as more extensive surgery for women with early-stage breast cancer that has spread to one or two sentinel lymph nodes (with cancer size > 2 mm). It aims to find a gentler treatment that still keeps the cancer from coming back.
Guiyang, GuizhouAges 18 years+
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Common questions
- Are there clinical trials for lymph node metastases?
- Yes. Clin2 currently lists 66 recruiting lymph node metastases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lymph node metastases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lymph node metastases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.