Clinical trials
Metabolic Disease clinical trials
Below are recruiting metabolic disease clinical trials, each written for real people, not researchers. We’re tracking 349 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07491172RecruitingPhase 1
Trial of CTX310 for stubborn high cholesterol and fats
This trial tests a new medicine, CTX310, for people with persistently high levels of fats (triglycerides) and cholesterol that have not improved with standard treatments. It aims to see if the drug is safe and tolerable.
Hialeah, FloridaAges 18–75 - NCT06568471RecruitingPhase 3
Study of HST101 for high cholesterol in Chinese patients
This study tests a new injectable medication called HST101 for lowering cholesterol in people who are already taking cholesterol pills but still have high levels. It may help if you have heart disease or are at high risk.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07417124RecruitingPhase 1
Study of SNS851 for people with high liver fat
This study tests a new medicine called SNS851 in healthy volunteers to see if it is safe and tolerable. It may help people with high liver fat, though it is not yet known if it works.
MelbourneAges 18–60 - NCT06833554Recruiting
Breast milk cells and infant health in mothers with metabolic conditions
This trial studies how special cells in breast milk from mothers with metabolic diseases (like obesity or diabetes) affect infant development and lung infection response after a nutritional intervention. It aims to understand if improving mother's diet can strengthen baby's immune system.
Málaga, MalagaAges 18–50 - NCT06546020Recruiting
Haskap berries for gut and metabolic health
This study tests whether a berry called Haskap can improve your gut health and how that might affect your overall health. Researchers are looking for people with and without certain metabolic risk factors to see who benefits most from adding these berries to their diet.
Bozeman, MontanaAges 35–65 - NCT07215533Recruiting
Exercise trials for teens and young adults at risk for diabetes
This study compares two types of exercise—high-intensity interval training (HIIT) and time-restricted eating (TRE)—to help lower the risk of developing type 2 diabetes in teens and young adults who are overweight or have obesity.
Syracuse, New YorkAges 14–30 - NCT06212479Recruiting
Whole-body MRI for Preventive Health Screening
This study uses whole-body MRI to see if it can find health issues early in people without symptoms. The goal is to learn if this scan can help predict clinically important conditions in routine preventive care.
Watertown, MassachusettsAges 18 years+ - NCT07124949Recruiting
Chinese migrant health study for older adults
This long-term study follows adults aged 60 and older who live in Harbin or Hainan to track their health over five years. It aims to understand health changes in this migrant population and does not involve any new treatments or drugs.
Harbin, HeilongjiangAges 60–120 - NCT07036692Recruiting
Weight loss study for adults with extra weight and health risks
This study tests a simple plan to help people with overweight and related health risks lose weight over a long time. You would follow the plan at home, chew a special gum, and send in a stool sample to see how your gut health changes.
BernAges 25 years+ - NCT05723913Recruiting
Test functional foods on blood sugar and gut bacteria
This study looks at how eating specific functional foods affects blood sugar after meals and changes in gut bacteria. It may help people understand ways to support healthy blood sugar and digestion, but it’s not for people with diabetes.
Mexico City, Mexico CityAges 18–60 - NCT06923644Recruiting
Personalized nutrition plan to prevent metabolic disease
This study tests whether a personalized nutrition plan based on your unique metabolism can help prevent chronic metabolic diseases like type 2 diabetes. You will follow a tailored diet and have your health monitored over time.
MaastrichtAges 40–75 - NCT06370312Recruiting
Biomarkers for thumb osteoarthritis surgery
This study looks at joint fluid and tissue samples from people with thumb base osteoarthritis who are already scheduled for a surgery called trapeziectomy. The goal is to find markers that might help better understand the disease and improve treatment.
Malmö, Skåne CountyAges 25 years+ - NCT06843902RecruitingPhase 2
Improving heart blood flow in women with HIV and diabetes or kidney problems
This trial tests a new approach to improve blood flow in the hearts of women with HIV who also have diabetes or kidney problems. It might help prevent heart disease in this population.
Boston, MassachusettsAges 45–75 - NCT06425042Recruiting
Nicotinamide riboside with exercise for healthy aging
This study tests whether a daily supplement called nicotinamide riboside (a form of vitamin B3), combined with a supervised exercise program, can help promote healthy aging and improve how well your body functions. You would take the supplement or a placebo for 12 weeks while doing light to moderate exercise.
Santiago, Santiago MetropolitanAges 60–80 - NCT04966351Recruiting
Study countermeasures for disrupted body clock timing
This study tests ways to help your body’s internal clock stay in sync when your sleep timing is off. It’s looking for healthy adults with fairly regular sleep and certain lifestyle and location history.
Fort Collins, ColoradoAges 18–35 - NCT06550115Recruiting
Night shift workers and their blood vessel & sugar health
This trial studies how sleep patterns affect blood vessel health and sugar control in long-term night shift workers. It may help find better ways to prevent heart problems and diabetes.
Fort Collins, ColoradoAges 18–65 - NCT06482944Recruiting
Whole-food diet program for families to prevent type 2 diabetes
This 12-week program helps parents with prediabetes and their children eat healthier whole foods based on U.S. dietary guidelines. The goal is to see if the program can lower the risk of developing type 2 diabetes in the family.
Nashville, TennesseeAges 6–59 - NCT06289348Recruiting
How is PKU announced to families after newborn screening?
This study talks to parents or doctors about how they first learned their child had PKU through newborn screening. It aims to improve how these rare metabolic diseases are communicated to families.
ParisAges 18 years+ - NCT06184646Recruiting
Prunes for bone health in postmenopausal women
This trial tests how many prunes per day can best improve bone health in postmenopausal women. It may help you if you have lower bone density but not severe bone loss.
San Diego, CaliforniaAges Any age - NCT06072911Recruiting
Men's health after prostate cancer surgery study
This study looks at how men recover control of urine and sexual function after prostate removal surgery. It also tests if a 12-week exercise program can help improve these functions.
Edmonton, AlbertaAges 18 years+ - NCT06003153RecruitingPhase 4
Gene and sugar response study with oral semaglutide
This study looks at how your genes affect your body's response to a diabetes medication called semaglutide. It may help people with slightly high blood sugar (pre-diabetes) understand why some respond better than others.
Boston, MassachusettsAges 18–65 - NCT05973539Recruiting
Study on how different foods change blood lipids
This study tests how your blood fat levels respond to changes in the types of nutrients you eat (carbohydrates, fats, and proteins). It may help researchers understand what dietary patterns best affect heart and metabolism-related blood measures.
OxfordAges 18–65 - NCT05711758Recruiting
Endoscopic stomach muscle cut for weight loss
This trial tests whether an endoscopic procedure that cuts a stomach outlet muscle can help with weight loss and be safe. You would be screened to make sure you don’t have certain stomach, heart/lung, or pregnancy-related conditions that could make the procedure unsafe.
Boston, MassachusettsAges 18–70 - NCT05600946Recruiting
Study of body differences in creatine transporter deficiency
This study looks at physical and body features in people with creatine transporter deficiency caused by a specific gene change (SLC6A8). It may help doctors better understand the condition and how it shows up, which can improve future care.
Bethesda, MarylandAges 2–40
Hear when a new Metabolic Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for metabolic disease?
- Yes. Clin2 currently lists 349 recruiting metabolic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.