Clinical trials
Metabolic Surgery clinical trials
Below are recruiting metabolic surgery clinical trials, each written for real people, not researchers. We’re tracking 66 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02166372Recruiting
Testing weight-loss surgery vs standard care for type 2 diabetes
This study compares people with type 2 diabetes and higher body weight who meet criteria for metabolic (weight-loss) surgery versus people with mild obesity who do not. It aims to see whether surgery improves diabetes-related outcomes more than usual medical care.
Taoyuan CityAges 20–67 - NCT07348146Enrolling by invitation
Hand-sewn vs. stapled bowel connection in SADI-S surgery
This trial compares two ways of reconnecting the intestine during SADI-S weight-loss surgery: one done by hand and one using staples. The goal is to see which method leads to fewer early problems after surgery, like leaks or infections.
CairoAges 18–70 - NCT02024542Recruiting
How the body changes after bariatric surgery
This study looks at how metabolism (how your body handles food and energy) responds after weight-loss surgery. It may help researchers understand what changes to expect in people with diabetes or prediabetes and cholesterol problems.
Sacramento, CaliforniaAges 18–55 - NCT06680492Recruiting
Nutrition and muscle health after weight loss surgery
This study looks at how nutrition affects muscle strength and function in people who have bariatric surgery. It may help you understand how to keep your muscles healthy after surgery.
Montreal, QuebecAges 18–65 - NCT06484621Recruiting
Preventing weight regain after weight loss surgery with exercise
This study looks at whether increased physical activity can help prevent weight regain after weight loss surgery. It is for people who had gastric bypass or sleeve gastrectomy in the last 6–20 months and have regained less than 10% of their lost weight.
Hartford, ConnecticutAges 18–64 - NCT06754709Recruiting
Protein Changes in Children Having Heart Surgery
This study looks at a specific protein change in blood and heart tissue of children having heart surgery with a heart-lung machine. The goal is to understand how this protein might affect recovery.
NantesAges Up to 17 years - NCT07223983RecruitingPhase 1
Semaglutide for alcohol use disorder after weight loss surgery
This trial tests if a once-weekly diabetes medication (semaglutide) can help people with alcohol use disorder who have had gastric bypass or sleeve gastrectomy in the past 7 years. It may reduce alcohol cravings or drinking.
New Haven, ConnecticutAges 18 years+ - NCT01477957Recruiting
Bariatric surgery and changes in insulin and body energy use
This study tests whether weight-loss surgery improves how your body uses insulin and energy. It compares insulin sensitivity and related measurements before and after surgery to understand who benefits.
Düsseldorf, North Rhine-WestphaliaAges 20–70 - NCT05551559Enrolling by invitation
How bariatric surgery changes liver metabolism in fatty liver disease
This study looks at how bariatric (weight-loss) surgery affects how your liver processes nutrients in people with non-alcoholic fatty liver disease. It may help researchers understand what changes in the body after surgery and whether that could guide better future care.
HelsinkiAges 18–75 - NCT07021248RecruitingPhase 4
Bariatric supplements after weight loss surgery
This study tests whether taking special supplements after weight loss surgery can help keep your vitamin levels healthy and avoid too much vitamin B6. If you are having your first weight loss surgery, you can join—as long as you are not pregnant, not allergic to B6, and meet the weight and health requirements.
Alexandria, EgyptAges 18–65 - NCT05650307Recruiting
Heart and metabolic scan study of weight and rehabilitation
This study uses detailed heart scans and information about metabolism (how your body uses energy) to understand how metabolic treatments and heart rehabilitation may affect your health. You may qualify either as someone undergoing bariatric (weight-loss) care or as part of a heart rehabilitation group—or as a healthy comparison group.
Cleveland, OhioAges 18 years+ - NCT06445413Recruiting
Tai Chi for weight loss surgery patients
This trial studies whether Tai Chi can help people who are waiting for weight loss surgery become more active. You would attend weekly Tai Chi classes at a Hartford HealthCare clinic for several weeks.
Hartford, ConnecticutAges 18–70 - NCT06829381Recruiting
Personalized one-anastomosis gastric bypass trial
This trial studies a personalized version of a common weight-loss surgery called One Anastomosis Gastric Bypass (OAGB). It aims to see if tailoring the surgery to each person improves results and safety.
Tel AvivAges 18 years+ - NCT05934409Recruiting
Measuring body-fat storage after bariatric surgery
This study looks at how body fat is stored and how that may relate to early improvements in diabetes and heart/liver health after bariatric surgery. It may help researchers understand why some people recover faster and which body changes matter.
Sherbrooke, QuebecAges 18–65 - NCT05987631Recruiting
Predicting weight loss and health after weight loss surgery
This study looks at why some people lose more weight and improve their health more than others after bariatric surgery. It also has a subgroup that specifically studies people who are insulin resistant (a sign of prediabetes) to see how surgery affects their metabolism.
Gouda, South HollandAges 18–75 - NCT06925997RecruitingEarly Phase 1
Bile acids after gastric bypass: metabolic effects study
This trial looks at how bile acids affect metabolism in people who have had gastric bypass surgery. It compares three groups: those who had diabetes before surgery, those without diabetes, and those with type 2 diabetes.
HvidovreAges 18 years+ - NCT04320264Recruiting
Study tests muscle fuel patterns in adults with BMI 25–30
This study looks at how your muscles use fuel during exercise by measuring blood lactate. It may help researchers understand “metabolic inflexibility” and why some people rely more on fast, short-lasting energy during activity.
Greenville, North CarolinaAges 18–50 - NCT06896682Recruiting
Cortisol and weight regain after weight-loss surgery study
This study looks at how cortisol affects blood sugar drops after weight-loss surgery. It may help explain links between cortisol, obesity, and low blood sugar episodes.
EsbjergAges Any age - NCT07239648Recruiting
Heart surgery and confusion after the operation
This study looks at confusion or disorientation (delirium) that can happen after heart surgery. It aims to learn more about who might be affected and how to improve recovery.
Xi'an, ShaanxiAges 18 years+ - NCT06747546Enrolling by invitation
Oxygen-based blood flow management after heart surgery
This study is testing a new way to manage blood flow after heart surgery in children with congenital heart disease. The goal is to make sure the body gets the right amount of oxygen to help recovery.
Minhang, Shanghai MunicipalityAges 1 week–18 years - NCT06226194Recruiting
Genes and weight loss after bariatric surgery
This study looks at how your genes might affect how much weight you lose after gastric sleeve or gastric bypass surgery. You may be able to help doctors better predict weight loss results for future patients.
Lleida, LeidaAges 18–65 - NCT07573930Recruiting
Blood sugar control during surgery with a common steroid
This study looks at how a steroid medication (dexamethasone) affects blood sugar levels during and after surgery. Researchers will use a continuous glucose monitor to track your blood sugar safely and understand how to better manage it in the operating room.
RoskildeAges 18 years+ - NCT04841057Enrolling by invitation
Study of blood and stool changes after weight-loss surgery
This study looks at how your body’s metabolism changes after a specific weight-loss surgery (gastric bypass). It may help researchers better understand what to expect and how to tailor care, while requiring blood draws and stool samples before and after surgery.
Columbia, MissouriAges 18–80 - NCT04444362Enrolling by invitation
Probacine to protect organs after cardiovascular surgery
This study tests whether a medicine called Probacine can help protect your gut and organs after cardiovascular surgery. If you qualify, you may be asked to take part and follow the study plan to see if complications are reduced.
Beijing, Beijing MunicipalityAges 18–90
Hear when a new Metabolic Surgery trial opens
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Common questions
- Are there clinical trials for metabolic surgery?
- Yes. Clin2 currently lists 66 recruiting metabolic surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.