Clinical trials
Microbiota clinical trials
Below are recruiting microbiota clinical trials, each written for real people, not researchers. We’re tracking 410 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05071131Recruiting
Inulin supplement to improve gut health in kidney disease
This trial studies whether taking inulin—a dietary fiber—can improve gut bacteria and the gut barrier in people with end-stage kidney disease on hemodialysis. It may help reduce gut-related problems that can affect overall health in kidney disease.
BerlinAges 18–75 - NCT05054361Recruiting
Study gut immunity changes in children with type 1 diabetes
This study looks at how a type of immune cell (MAIT cells) and the gut (microbiota and gut lining) change around the time type 1 diabetes starts in children. It may help researchers understand why type 1 diabetes begins and how the gut and immune system are connected.
AntonyAges 1–15 - NCT04117321Recruiting
Study of mother-to-baby gut germs and baby health
This study looks at how germs in a mother can be passed to her baby and whether that affects the baby’s health. If you join, your baby (and the other parent or legal guardian) may be asked to share consent so researchers can follow the pregnancy and early life.
Hong Kong, Hong KongAges Any age - NCT05533983Recruiting
Stool transplant plus nivolumab for advanced solid cancers
This study tests whether transferring stool microbiome (“FMT,” stool transplant) along with nivolumab can improve outcomes in people with advanced solid cancers that kept worsening even after anti–PD-1/PD-L1 treatment. It also looks at stool and blood changes to understand why the treatment might work.
SeoulAges 19 years+ - NCT04264975Recruiting
Using gut microbiome tests and stool transfer in immunotherapy cancer
This trial studies whether changes in gut bacteria can help predict how well immunotherapy works for solid cancers. It also tests whether stool (fecal microbiota) from certain immunotherapy-responding people can improve outcomes for others who are not responding well.
Seoul, SeoulAges 19 years+ - NCT04188743RecruitingPhase 2/Phase 3
Stool transplant to clear antibiotic-resistant gut germs
This trial tests whether a stool (fecal) transplant from a screened donor can help remove antibiotic-resistant gut bacteria (MDRO) that keep coming back in your stool tests. It aims to reduce colonization that makes follow-up and treatment harder.
Ghent, Oost-VlaanderenAges 18 years+ - NCT06448468Recruiting
Eye microbes in dry eye after LASIK
This study looks at the bacteria and other microbes on the eye's surface in people who develop dry eye after LASIK surgery. It aims to understand how these microbes change and may help improve future treatments for dry eye after LASIK.
Nanchang, JiangxiAges 18–45 - NCT06122207Recruiting
Probiotic for women with fertility issues and IVF
This study tests whether a probiotic (a pill with beneficial bacteria) can help improve the health of the female genital tract for people with fertility problems who are undergoing IVF. It aims to see if this can improve chances of pregnancy.
LisbonAges 18–45 - NCT03148743Recruiting
Fecal transplant for gut graft-versus-host disease
This study tests whether a fecal transplant (FMT) can help treat gut graft-versus-host disease (gut GVHD), a condition where donated immune cells attack the intestines. If you have gut GVHD and meet age requirements, you may be eligible to receive this treatment in the trial.
Suzhou, JiangsuAges 10–60 - NCT07453823Recruiting
Synbiotic for gut health in overweight adults
This trial tests a combination supplement (a synbiotic) to see if it can improve gut function and gut bacteria in middle-aged and older adults who are overweight and have constipation. If eligible, you take the supplement daily and report how your digestion feels.
Cork, BlackpoolAges 50–70 - NCT05911997RecruitingPhase 1
Compare stool treatment options for repeat C. difficile infection
This Phase 1 study tests a stool-based treatment approach for people who keep getting C. difficile diarrhea that returns after antibiotics. The goal is to see whether the treatment is safe and works to stop future episodes.
New York, New YorkAges 18 years+ - NCT07687940Recruiting
Baduanjin exercise and green tea for mood in older adults
This study tests if doing gentle Baduanjin exercises and drinking green tea together can help improve mood and quality of life in older adults. It also looks at how this program affects gut health.
Kwun TongAges 65–84 - NCT07196189Recruiting
Fecal transplant for eating disorders
This study tests whether a fecal microbiota transplant (transferring healthy donor stool into your gut) can help treat eating disorders like anorexia, bulimia, or binge eating disorder. It is for women ages 18 to 50 who have not had antibiotics in the last 3 months.
RouenAges 18–50 - NCT07085299Recruiting
Gut bacteria and recovery in brain artery narrowing
This study looks at how the bacteria in your gut might affect outcomes in people with narrowed brain arteries. Researchers will track your health over time to see if there are links between your gut bacteria and your recovery.
Nanjing, JiangsuAges 30–80 - NCT07156422Recruiting
Study of sensitive scalp in women without skin disease
This study is for women who have a sensitive scalp — feeling itchy, burning, or uncomfortable — but no scalp disease like psoriasis. Researchers want to understand what causes this sensitivity so they can help people like you.
BrestAges 18 years+ - NCT06642883Recruiting
A supplement for gut health in ulcerative colitis remission
This study tests a supplement called ProLife 10 FORTE to see if it affects the natural balance of gut bacteria in people with ulcerative colitis (UC) that is in remission. If you have UC that is not active and you meet other health criteria, you may be able to join.
Padua, PaduaAges 18–75 - NCT05786404RecruitingPhase 1
Fecal transplant study for people with active ulcerative colitis
This trial tests whether transplanting stool bacteria (called fecal microbiota transplantation, or FMT) can improve symptoms in people with active ulcerative colitis. You may be able to help test a new approach for restoring gut bacteria, while receiving standard ulcerative colitis care from your doctor.
Houston, TexasAges 18 years+ - NCT06423508Recruiting
Testing stool storage methods and gut bacteria differences
This trial will study how different storage methods affect stool samples for gut bacteria analysis. It aims to understand differences in gut bacteria between people over time. Participation involves providing stool samples.
Vienna, State of ViennaAges 18–70 - NCT06157346Recruiting
Gut bacteria and growth in high-altitude children
This study looks at how gut bacteria affect growth and immune health in children aged 1 to 3 living at high altitudes. It may help find ways to support healthy development.
Shanghai, Shanghai MunicipalityAges 1–3 - NCT06673199Recruiting
Japanese diet and gut health in postmenopausal women
This study tests whether a traditional Japanese diet called 'washoku' can change the gut bacteria in postmenopausal women who are overweight. It may help improve health after menopause.
Poznan, WielkopolskaAges 45–65 - NCT04792320Recruiting
Probiotics and fiber for kidney disease with leg artery blockage
This study tests whether an oral absorbent plus probiotics can improve gut health and circulation in people who have chronic kidney disease and symptomatic peripheral artery disease (PAD). It will also track changes in blood markers and how well blood vessels function.
TaipeiAges 20 years+ - NCT07443280Recruiting
Gut health supplement study for dialysis patients
This trial tests whether a special blend of probiotics and prebiotics (called a synbiotic) can improve gut health and reduce harmful waste products in the blood for people on hemodialysis.
Taichung, Wuqi DistrictAges 18 years+ - NCT07439640Recruiting
PEG laxatives for bowel prep and gut health after gallbladder removal
This study looks at how a common bowel prep medicine (PEG laxatives) affects gut bacteria in people who have had their gallbladder removed compared to those who still have one. It involves collecting stool samples before and after a colonoscopy to track changes over time.
Wuhan, HubeiAges 18–65 - NCT07416760Recruiting
Gut bacteria study after intestinal surgery
This study looks at how gut bacteria change after surgery to reconnect the intestines (anastomosis). It may help doctors understand complications and improve recovery.
MadridAges 18 years+
Hear when a new Microbiota trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for microbiota?
- Yes. Clin2 currently lists 410 recruiting microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.