Clinical trials
Mild Traumatic Brain Injury clinical trials
Below are recruiting mild traumatic brain injury clinical trials, each written for real people, not researchers. We’re tracking 125 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04982731Enrolling by invitation
Testing reassurance support after a concussion in teens
This study looks at whether a specific reassurance program (“Positive Assurance”) helps teens recover better after a mild concussion. Teens are checked for concussion symptoms, then assigned to different support approaches to see which helps most.
Falls Church, VirginiaAges 13–21 - NCT04043442Enrolling by invitationPhase 2
Brain stimulation study for alcohol use with mild brain injury
This trial tests a type of brain stimulation to help with day-to-day functioning in people who have alcohol use disorder and a history of mild traumatic brain injury. It also uses brain and symptom testing to see who may benefit most and why.
Hines, IllinoisAges 22–65 - NCT07215195Recruiting
Brain injury, sleep, and mental health study
This study looks at how brain injuries affect sleep and mental health in the months after injury. It is for people who have had a stroke, brain bleed, or traumatic brain injury within the past year and are willing to let the research team contact their doctor if needed.
OxfordAges 18 years+ - NCT06792877Recruiting
Mindfulness for thinking in early Alzheimer's
This study tests if mindfulness training can help protect thinking and memory in early-stage Alzheimer's disease. It compares mindfulness to other activities to see if it slows down memory loss.
Boston, MassachusettsAges 50–100 - NCT06860828Enrolling by invitation
Football players and brain health study: DIAGNOSE CTE
This study looks at brain changes in former college and professional football players, people with memory problems, and healthy controls. It aims to learn more about chronic traumatic encephalopathy (CTE) and Alzheimer's disease.
Phoenix, ArizonaAges 50 years+ - NCT05323149RecruitingPhase 3
Tranexamic acid for non-penetrating brain injury after trauma
This Phase 3 study tests whether tranexamic acid can improve outcomes after traumatic brain injury. It may help by reducing bleeding and related damage soon after the injury in adults with mild to moderate cases.
Asyut, AssuitAges 18–65 - NCT06465290Recruiting
Brain recovery treatment for recent stroke with ankle stiffness
This trial tests a treatment to help your brain recover after a stroke. It focuses on improving ankle movement and leg strength using exercises that promote brain rewiring.
Baltimore, MarylandAges 30–85 - NCT05176392Recruiting
Stimulation treatment plus therapy for post-injury headaches
This study tests whether a noninvasive brain stimulation treatment combined with therapy can reduce long-lasting headaches after a mild brain injury. You might be a good candidate if your headaches started after the injury and have continued for months.
San Diego, CaliforniaAges 18–65 - NCT05628207Recruiting
Test of an acceptable care-scaling plan for people with brain injury
This trial looks at a care approach to see if it is acceptable and workable for adults admitted to the hospital with a traumatic brain injury. It may help improve how care is scaled and delivered after TBI.
Minneapolis, MinnesotaAges 18 years+ - NCT06028334Recruiting
GetUp&Go: Helping you get active after a brain injury
This study tests a program to help people with traumatic brain injury become more physically active. You would use a smartphone app and get coaching to increase your daily movement, which may improve your recovery and quality of life.
Elkins Park, PennsylvaniaAges 18 years+ - NCT06034509Recruiting
Thinking and blood vessel health after head injury
This study looks at how a past traumatic brain injury (TBI) might affect your thinking skills and blood vessel health over time. You may be eligible if you had a TBI at least 3 years ago and have already completed an earlier evaluation at the National Intrepid Center of Excellence (NICoE).
Bethesda, MarylandAges 18–74 - NCT06148324Recruiting
Wellness program for traumatic brain injury recovery
This study tests a wellness program for people who had a moderate or severe traumatic brain injury (TBI) at least a year ago. The program is done online, so you can join from home, and it aims to help you with your recovery and well-being.
New York, New YorkAges 18–70 - NCT06562127Recruiting
Water exercise and cognitive training for veterans with TBI
This trial tests if combining water-based exercise with cognitive training over eight months can help improve thinking and memory in veterans with a past mild or moderate brain injury. It may benefit veterans aged 50-89 who have ongoing cognitive complaints.
Palo Alto, CaliforniaAges 50–89 - NCT06723743Recruiting
Nerve stimulation for attention and memory
This study tests if a gentle, non-invasive nerve stimulation device can help improve attention and memory in veterans with PTSD, depression, or mild brain injury. It uses a small device on the ear to stimulate a nerve that may influence brain function.
Houston, TexasAges 25–64 - NCT06828107Recruiting
Testing a device to detect traumatic brain injury
This study tests a new device called SENSE to see if it can detect traumatic brain injury (TBI) quickly. You may qualify if you have a TBI with bleeding seen on a CT scan, or if you are a healthy volunteer without brain problems.
Gainesville, FloridaAges 22 years+ - NCT07332299Recruiting
Brain stimulation and training for seniors with TBI
This study tests if a wearable brain stimulation device (tDCS) combined with computer-based training can improve attention and concentration in older veterans with a history of mild brain injury. It involves several sessions from home using a headset and computer.
Minneapolis, MinnesotaAges 65 years+ - NCT05380050Recruiting
Telehealth vs in-person skills training for brain injury and PTSD
This study compares a combined skills program delivered by video/phone (telehealth) versus meeting in person. It aims to improve attention and coping skills for veterans who have both mild brain injury and PTSD.
Gainesville, FloridaAges 30–55 - NCT05910619Recruiting
Noninvasive brain stimulation to support memory and thinking
This study tests a noninvasive way of stimulating the brain to see if it can help older adults with typical age-related changes or mild memory problems. You may be invited if your screening tests and health history fit one of their target groups.
Gainesville, FloridaAges 65–84 - NCT03957343Recruiting
Parkwood Pacing and Planning app for concussion recovery
This study tests a smartphone or tablet app (the Parkwood Pacing and Planning app) that may help people after a mild concussion manage recovery. You may be able to join if you’re an adult, can use the app device, and have a confirmed mild concussion.
London, OntarioAges 18 years+ - NCT07065916Enrolling by invitation
Arm More + Camp: Helping kids with arm weakness
This trial tests a program called 'Arm More + Camp' to help kids and teens with arm weakness due to cerebral palsy or a brain injury improve their movement. It’s a group camp-style study that fits into the school year.
Calgary, AlbertaAges 5–17 - NCT06852300Enrolling by invitation
Concussion recovery study for athletes
This study looks at how athletes recover from concussions or mild traumatic brain injuries. It aims to understand recovery patterns, which could help improve care for sports-related head injuries.
Conway, ArkansasAges 18–26 - NCT03954899Recruiting
Melatonin test for brain health in older adults
This study tests whether taking 5 mg of melatonin can improve thinking and brain health over time in older adults with early, mild symptoms. You may help researchers learn which brain changes and measures improve with melatonin.
Iowa City, IowaAges 56–85 - NCT02670161Enrolling by invitationPhase 4
Using electronic records to improve care for brain and nerve conditions
This study looks at how doctors use electronic medical records to improve treatment and care for people with certain brain and nervous system conditions. It may help because it tests practice-based approaches across neurology visits.
Evanston, IllinoisAges 18–100 - NCT05710549Recruiting
Brain study of autobiographical memory using brain stimulation
This study looks at how the brain supports remembering your own past experiences. It tests brain mechanisms using brain scanning (MRI) and noninvasive brain stimulation to see how these memory processes work.
Geneva, Canton of GenevaAges 18–85
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Common questions
- Are there clinical trials for mild traumatic brain injury?
- Yes. Clin2 currently lists 125 recruiting mild traumatic brain injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild traumatic brain injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild traumatic brain injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.