Clinical trials
Muscle clinical trials
Below are recruiting muscle clinical trials, each written for real people, not researchers. We’re tracking 1,109 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06840262Recruiting
Nerve surgery for pain after cancer amputation
This study tests two surgical techniques—target muscle re-innervation and regenerative peripheral nerve interfaces—alone or together, to help reduce pain felt in the remaining limb or the missing limb (phantom pain) after amputation for cancer. The goal is to find the best way to manage pain and improve quality of life.
Houston, TexasAges 18 years+ - NCT06631820Recruiting
A study of epicatechin for muscle health in advanced kidney disease
This trial tests whether a natural supplement called epicatechin can improve muscle health in people with advanced chronic kidney disease (CKD). You may be able to join if you have low kidney function and are not planning to start dialysis or have a kidney transplant in the next 4 months.
Huddinge, Stockholm CountyAges 60 years+ - NCT06827379Enrolling by invitation
Breathing exercise for muscle and nerve health in COPD
This trial tests whether a special breathing exercise (inspiratory muscle training) can improve how your muscles work and your body's automatic responses, like heart rate. It's a one-time session for people with stable COPD.
João Pessoa, ParaíbaAges 40–75 - NCT06815367Recruiting
Compression vs Blood Flow Restriction for Muscle Recovery
This study compares two methods to help muscles recover after exercise: pneumatic compression (like a gentle massage sleeve) versus blood flow restriction (using a cuff). It aims to find which works better for healthy, active young adults.
Los Angeles, CaliforniaAges 18–30 - NCT06809140RecruitingPhase 2
Bladder-sparing treatment for muscle-invasive bladder cancer
This trial tests a combination of two drugs, enfortumab vedotin and pembrolizumab, to treat bladder cancer that has grown into the muscle of the bladder. The goal is to shrink or eliminate the cancer so that surgery to remove the bladder may not be needed.
Duarte, CaliforniaAges 18 years+ - NCT06812611Recruiting
High intensity laser therapy for muscle injuries
This trial tests if high intensity laser therapy helps heal severe muscle tears in the leg. If you have a recent, serious muscle tear from sports, this treatment might speed up your recovery.
BariAges 16 years+ - NCT05929755RecruitingPhase 4
Depo-Medrol after lumbar surgery through the psoas muscle
This trial studies whether a steroid shot called Depo-Medrol, given after a specific type of lower-back surgery, can improve recovery and outcomes. It’s only for people who are having a certain lumbar fusion procedure at specific spinal levels.
Farmington, ConnecticutAges 18–75 - NCT06205147Recruiting
Elastic band exercise for strength and mood in older hospital patients
This study tests whether using elastic bands for resistance exercises can help older adults in the hospital improve their muscle strength and reduce symptoms of depression. If you are 65 or older, staying in the hospital for more than a week, and able to follow simple instructions, this might be a good fit.
Taipei, TaiwanAges 65 years+ - NCT06774157Enrolling by invitation
Allyane therapy for knee sprain recovery
This trial tests if the Allyane procedure helps people with a recent knee sprain regain thigh muscle strength. It may be an option if you have weakness in the front thigh muscle compared to your uninjured leg.
LyonAges 18–35 - NCT06777134Recruiting
Pelvic floor issues and leg strength in MS patients
This study looks at how pelvic floor problems relate to leg strength and function in people with multiple sclerosis. It may help understand how to better treat these issues.
Istanbul, IstanbulAges 18–65 - NCT06781879RecruitingPhase 4
Comparing bladder medication vs surgery for returning low-grade bladder cancer
This trial tests whether a chemotherapy drug placed directly into the bladder (chemoablation) works as well as surgery followed by chemotherapy for people whose low-grade bladder tumors have come back. It aims to find a less invasive option that still controls the cancer.
AalborgAges 18 years+ - NCT06780423Recruiting
Muscle changes in colorectal cancer cachexia
This study compares muscle changes in people with colorectal cancer who have experienced weight loss (cachexia), those with colorectal cancer without weight loss, and healthy volunteers. Participants will have their trunk and leg muscles examined to understand how cachexia affects the body.
Diepenbeek, LimburgAges 18 years+ - NCT06770582RecruitingPhase 2
Adding immunotherapy to radiation for bladder cancer
This trial tests whether adding the immunotherapy drug pembrolizumab to radiation therapy works as well as or better than the usual chemotherapy given with radiation for a type of bladder cancer that has not invaded the muscle. It is for people whose cancer came back or has high-risk features and who would otherwise need to have their bladder removed.
Tucson, ArizonaAges 18 years+ - NCT06758791Enrolling by invitation
Breathing, balance, and walking after stroke
This study looks at how breathing muscle function relates to balance and walking in people who have had a stroke. It may help find new ways to improve recovery.
Istanbul, BüyükçekmeceAges 18–80 - NCT06719245Recruiting
Preventing post-amputation pain with targeted nerve surgery
This trial tests a surgical procedure called targeted muscle reinnervation (TMR) to prevent pain after a leg amputation. The goal is to see if rerouting nerves during amputation can reduce phantom limb pain or stump pain.
Amsterdam, North HollandAges 18–75 - NCT06714240Recruiting
Extra protein to support muscle strength in ICU
This study tests whether giving extra protein through a feeding tube can help ICU patients maintain muscle strength. It may be an option for people who are expected to stay in the ICU for at least a week and need a breathing machine.
Hasselt, LimburgAges 18 years+ - NCT06705790Recruiting
Pelvic floor training for bladder, bowel, and sexual health after spinal cord injury
This study tests whether pelvic floor muscle exercises can improve bladder, bowel, and sexual function in people with a spinal cord injury. If you have ongoing symptoms in these areas and a stable health routine, this trial may help you learn ways to strengthen those muscles.
Vancouver, British ColumbiaAges 19 years+ - NCT05293366Recruiting
Long COVID study testing supportive care for multiple body systems
This study looks at people who have recovered from COVID-19 but still deal with long-term problems. It aims to better understand (and potentially help with) ongoing issues that can affect hormones, metabolism, mood, muscles, the heart, lungs, and skin.
NaplesAges 18 years+ - NCT06682728RecruitingPhase 2
Treating high-risk bladder cancer after surgery
This trial tests a combination of two drugs (sacituzumab govitecan and nivolumab) given after surgery to prevent the return of muscle-invasive bladder cancer. It is for patients whose cancer has a high chance of coming back despite surgery.
Orange, CaliforniaAges 18 years+ - NCT06666881Recruiting
Exercise training for head and neck cancer patients
This trial studies if exercise training can improve outcomes for people with head and neck squamous cell cancer who need chemotherapy and radiation. It uses body scans to see if muscle changes from exercise are linked to better prognosis.
New Taipei CityAges 20–80 - NCT06656130Enrolling by invitation
Breathing and relaxation for pre-hypertension
This trial tests two gentle techniques—deep breathing (Pranayama) and progressive muscle relaxation—to see if they can help lower blood pressure in people with pre-hypertension. You would attend practice sessions and follow-up visits.
Sialkot, Punjab ProvinceAges 30–60 - NCT06627283Recruiting
Does breathing muscle training help tongue muscles?
This trial tests whether training the muscles you use to breathe can also improve your tongue muscle function. It looks for healthy adults between 18 and 65 who can follow instructions in French or Dutch.
LeuvenAges 18–65 - NCT06628674Recruiting
Online videos for recovery after rectal cancer surgery
This trial tests if watching online interactive videos can help people who have had surgery for stage I to III rectal cancer deal with common bowel problems after treatment. Your participation could lead to better support tools for other patients.
Taoyuan, 中和區Ages 20 years+ - NCT06571708RecruitingPhase 2
Chemo plus immunotherapy for muscle-invasive bladder cancer
This trial tests adding two immunotherapy drugs (cemiplimab and fianlimab) to standard chemotherapy (gemcitabine and cisplatin) for people with bladder cancer that has grown into the muscle layer but hasn't spread. The goal is to see if adding these immunotherapies helps shrink the tumor before surgery.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for muscle?
- Yes. Clin2 currently lists 1,109 recruiting muscle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.