Clinical trials
Muscle clinical trials
Below are recruiting muscle clinical trials, each written for real people, not researchers. We’re tracking 1,160 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03808584Recruiting
Core muscle training after abdominal surgery to reduce hernia and pain
This study tests whether guided “core” muscle training after abdominal surgery can lower the chance of developing an incisional hernia and reduce pain. You may be eligible if you’re having abdominal surgery and can safely do the study exercise plan.
KoblenzAges 18 years+ - NCT04658498Recruiting
Respiratory muscle training to help patients come off the ventilator
This trial studies whether exercises for breathing muscles can help people who are having a hard time coming off a breathing machine in the ICU. It may help you breathe with less ventilator support once your body is stable enough.
LeuvenAges 18 years+ - NCT02611089Recruiting
Study of forearm development and reconstruction in limb conditions
This study looks at how connective tissue in the forearm develops and how it behaves in people needing reconstructive surgery. It may help surgeons better plan and improve reconstruction for conditions like radial dysplasia, or for other injuries requiring similar surgery.
Oxford, OxfordshireAges Any age - NCT07294131RecruitingPhase 2
Preventing muscle loss in hospitalized older adults
This trial tests a special exercise approach using blood-flow restriction and a video game to help older adults in the hospital keep their muscle strength. The goal is to find a safe way for bedridden patients to exercise and recover better.
AntwerpAges 65 years+ - NCT07108920Recruiting
Balance and Botox for Stiff Knee Gait
This study tests whether botulinum toxin (Botox) injections into the rectus femoris thigh muscle can improve balance and walking in people with a stiff knee gait (a common problem after stroke, brain injury, or multiple sclerosis).
Héricourt, Nord Franche-ComtéAges 18 years+ - NCT07155967Enrolling by invitation
Blood flow restriction training for leg strength in older women
This trial tests whether a type of strength training that partly uses blood flow restriction can help older women build leg strength on one side, which may also benefit the other leg. It's for women who are generally healthy and have not had recent leg injuries or surgeries.
Presidente Prudente, São PauloAges 60 years+ - NCT03121404Recruiting
Study causes of poor nutrition in people with liver scarring
This study looks at why some people with cirrhosis (liver scarring) develop malnutrition, especially when blood flow is redirected during certain surgeries. It may help explain what contributes to low body weight and muscle so better treatments can be planned in the future.
Cleveland, OhioAges 18–70 - NCT06204614Enrolling by invitationEarly Phase 1
Drug screening for bladder cancer before surgery
This trial tests a tiny device placed into bladder tumors before surgery to see which drugs might work best for each patient, helping guide future treatment choices.
Boston, MassachusettsAges 18–120 - NCT03672760Recruiting
Breathing training app for heart vessel stiffness and stress signals
This study tests whether an inspiratory (breathing-in) muscle training program using the CardioBreath app can improve heart blood-vessel stiffness and “stress/autonomic” signaling. It targets people with a specific hormone pattern and activity level, while avoiding several common health conditions that could affect safety or results.
Porto Alegre, Rio Grande do SulAges 45–65 - NCT06475391Recruiting
L-arginine supplement for exercise performance
This study tests whether taking L-arginine (a natural amino acid supplement) can improve your performance during short, intense exercise like sprinting or weightlifting. If you are a healthy, active adult, you may be able to join.
Winnipeg, ManitobaAges 18–39 - NCT06536803Recruiting
Strength training with or without stretching for plantar fasciitis
This study tests whether adding specific stretches for the plantar fascia to high-load strength training helps male athletes with plantar fasciitis feel better. It compares strength training alone to strength training plus targeted stretching.
Mirpur MatheloAges 20–35 - NCT07419633Recruiting
Study on supplements to improve strength and thinking in older adults
This trial tests if two supplements, HMB and 2-HOBA, taken alone or together, can help improve muscle strength and mental function in healthy adults over 65. The goal is to see if these supplements can improve overall quality of life.
Montreal, QuebecAges 65 years+ - NCT07297771Recruiting
Shoulder muscle activity during different exercises
This trial looks at how a specific shoulder muscle works during different exercises. It may help people understand better ways to strengthen or rehab the shoulder.
Ankara, AltındagAges 18–40 - NCT06806514Recruiting
Exercise and muscle strength in chronic low back pain
This trial measures how well you can use your arms and how strong your breathing and other muscles are if you have chronic low back pain. It aims to understand the links between these factors to improve future treatments.
KırşehirAges 18–65 - NCT06808022Enrolling by invitation
Back exercises before spine surgery
This trial studies whether doing back exercises before spine surgery helps improve recovery. If you are having spine surgery and can safely do physical therapy, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT06727708Recruiting
Comparing two exercise programs for fitness in adults 30-65
This study is testing two different 12-week exercise programs to see which one better improves physical fitness and body composition. It might be a good fit if you're a healthy adult aged 30-65 who is new to strength training.
Leibnitz, Styria, StyriaAges 30–65 - NCT06083766Recruiting
Hormone Therapy Effects on Metabolism in Transgender Adults
This study looks at how long-term gender-affirming hormone therapy affects your body's metabolism and energy use. Researchers want to understand these changes better to improve care for transgender and gender-diverse people.
Rochester, MinnesotaAges 18–40 - NCT07486830RecruitingPhase 2
Botox for Painful Vestibulodynia with Tight Pelvic Floor Muscles
This trial tests whether Botox (incobotulinumtoxinA) can help reduce pain in women with provoked vestibulodynia (pain at the vaginal opening) and overactive pelvic floor muscles. If you qualify, you will receive an injection and be monitored for improvement.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07267364Recruiting
Pelvic floor exercises for children with bladder issues
This study tests two types of exercises to help children with bladder control problems. It compares standard pelvic floor training with a special exercise approach that may improve how the bladder and muscles work together.
Konya, KonyaAges 5–18 - NCT07095725Recruiting
Effect of Period Pain on Muscle Activity in Young Women
This trial studies how primary dysmenorrhea (period pain) affects muscle activity in young women aged 18-25. It may help understand why period pain happens and guide future treatments.
GizaAges 18–25 - NCT07522398Recruiting
Power Training Study for Adults Over 65
This study tests whether short, intense strength exercises can help older adults build muscle and stay stronger. You'll do exercises designed to build power (the ability to move quickly and forcefully) over several weeks, and researchers will measure changes in your strength and daily function.
Diepenbeek, FlandersAges 65–85 - NCT07600359Recruiting
Physical therapy techniques for sacroiliac joint pain
This study compares two hands-on physical therapy techniques to reduce lower back pain, improve walking, and restore function in people with sacroiliac joint dysfunction (a condition affecting the joint connecting your spine to your pelvis). You'll receive treatment and be assessed to see which technique works better.
Islamabad, Punjab ProvinceAges 25–45 - NCT07646405Recruiting
Electrical stimulation and light resistance training for older adults' muscles
This study tests whether combining electrical muscle stimulation (a gentle electrical current applied to muscles) with light resistance exercises can help adults over 65 build stronger leg muscles and improve their ability to walk and move around.
Lahore, Punjab ProvinceAges 65–85 - NCT07225803Recruiting
Managing pelvic floor muscle problems that cause constipation
This study tests a treatment for a specific type of constipation caused by pelvic floor muscles not working together properly (dyssynergic defecation). It aims to help people who strain or feel blocked when trying to have a bowel movement.
Rochester, MinnesotaAges 18–80
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Common questions
- Are there clinical trials for muscle?
- Yes. Clin2 currently lists 1,160 recruiting muscle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.