Clinical trials
Musculoskeletal Pain clinical trials
Below are recruiting musculoskeletal pain clinical trials, each written for real people, not researchers. We’re tracking 101 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07356115Recruiting
Pain patterns and pain location in muscle and sports clinics
This study looks at whether people's pain patterns—measured by a simple questionnaire called PainDETECT—are linked to where their pain is and what caused it. It may help doctors better understand and treat different types of pain.
IstanbulAges 18 years+ - NCT06175884Recruiting
Communication skills for chronic muscle and joint pain
This trial tests how a physical therapist's communication style affects pain and function in people with long-term muscle or joint pain. Participants will fill out questionnaires and watch a video to see if better communication improves outcomes.
LamiaAges 18–65 - NCT07756229Recruiting
Physiotherapy for long-term neck pain
This study looks at how physiotherapy affects brain activity and symptoms in people with chronic neck pain lasting more than 3 months. It aims to see if physiotherapy can help reduce pain and improve function.
San Sebastián, GuipuzcoaAges 18 years+ - NCT06906107Recruiting
Neck pain study: testing a personalized treatment approach
This study is testing a method to see which neck pain patients benefit most from manual therapy and exercise. You may be eligible if you have neck pain (with or without arm symptoms) and have not had recent whiplash, neck surgery, or certain other conditions.
Rochester, MinnesotaAges 18–70 - NCT06119698Recruiting
Improving Health for Older Adults With Pain Through Engagement
This study tests a program to help older adults with long-lasting bone, joint, or muscle pain become more active. Participants wear a smartwatch and get support to manage their pain and improve their health.
Boston, MassachusettsAges 55 years+ - NCT06500780Recruiting
Pain and depression support for African Americans
This study tests a program that helps people with both long-term pain and depression. It includes coaching and support to help you feel better and manage your health. The study is for Black or African American adults.
Indianapolis, IndianaAges 18 years+ - NCT06867757Recruiting
Chronic pain in youth study
This study tests a new way to understand and track chronic pain in young people using real-time feedback. It may help your healthcare team better manage your pain.
Palo Alto, CaliforniaAges 14–24 - NCT06512727Recruiting
Pain management study for Black older adults with long-term joint pain
This study tests two different approaches to help Black adults aged 50–92 manage chronic muscle or joint pain in their hips, knees, lower back, or ankles. It aims to find which method works better to reduce pain and improve daily life.
Gainesville, FloridaAges 50–92 - NCT07008105Recruiting
One session therapy for chronic pain
This study tests whether a single 90-minute online session can help people with chronic pain feel better. If you live with ongoing pain and want to try a brief psychological approach without medication, you may be a good fit.
Chicago, IllinoisAges 18 years+ - NCT06870162Recruiting
Pain disengagement training: a writing study for chronic pain
This study tests a writing-based program to help people with chronic pain learn to disengage from pain-related thoughts. It aims to reduce pain catastrophizing and improve daily function.
Boston, MassachusettsAges 18 years+ - NCT06297447Recruiting
Keeping it Simple: rehab for chronic pain
This study looks at how to better help people with ongoing muscle or joint pain who are getting rehabilitation through their local municipality. The goal is to learn what works best for you.
Holbæk, Region SjællandAges 18 years+ - NCT07685418Recruiting
Pressure therapy and home exercises for neck pain
This trial tests whether a hands-on technique called ischemic compression (applying gentle pressure to trigger points) plus home exercises helps relieve long-term neck pain that has no specific medical cause.
Istanbul, BakırköyAges 17–65 - NCT06886906Recruiting
Movement and Pain in Older Adults
This study explores how movement and physical activity relate to pain in older adults with muscle or joint pain. It could help you understand your pain patterns and find better ways to manage them.
Indianapolis, IndianaAges 55–85 - NCT07331766Enrolling by invitation
Collaborative care for chronic pain patients
This trial tests a team-based treatment approach for people with chronic pain. You'll work with at least two pain clinic specialists to create a care plan that fits your needs.
Ottestad, InnlandetAges 18 years+ - NCT07218757Recruiting
Trial of emotional awareness therapy for veterans with chronic pain
This study tests if a type of therapy that helps you understand and express emotions related to pain (called Emotional Awareness and Expression Therapy) can reduce chronic pain in veterans. It is designed for veterans who have had muscle or joint pain for at least 3 months and rate their pain as moderate or greater.
Los Angeles, CaliforniaAges 18 years+ - NCT07602595Recruiting
Understanding pain after childhood rheumatic disease or surgery
This study helps researchers learn how young adults (ages 14–26) who had rheumatic disease or orthopedic surgery as children experience pain over time. By understanding your story, the study may help doctors better support others facing similar challenges.
Cincinnati, OhioAges 14–26 - NCT07048366Recruiting
Mindfulness in a museum for fibromyalgia pain relief
This study tests whether a mindfulness program held in a museum setting can help women with fibromyalgia feel less pain and improve their quality of life. You would attend sessions in a museum and practice mindfulness techniques.
Chieti, AbruzzoAges 18–60 - NCT07193095Recruiting
Comparing two brief pain relief programs for chronic pain
This study compares two brief programs (mindfulness skills vs. pain relief education) to see which helps adults with chronic muscle or joint pain feel better. You would attend one or two sessions and complete short questionnaires, all from home.
Tallahassee, FloridaAges 18 years+ - NCT06936059Recruiting
Chronic pain rehab app for musculoskeletal pain
This study tests a software program that helps train people with chronic muscle or joint pain. It uses mixed reality (like special glasses) to guide you through exercises at home. If you have ongoing pain and can read Chinese, you may qualify.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07605013Recruiting
Neck Exercises for Office Workers: Building Strength and Function
This study tests whether specific neck mobilization techniques (gentle movements and stretches) can improve neck strength and function in desk workers. You would be a healthy control participant to help researchers understand how these techniques work in people without existing neck pain.
IstanbulAges 18–40 - NCT05555576Recruiting
Vitamin C to reduce opioid use after an ER visit
This trial tests whether taking vitamin C after an emergency room visit for a new, short-term muscle or joint pain can lower how many opioid pain pills you use. It may help by reducing opioid consumption while you recover.
Montreal, QuebecAges 18 years+ - NCT06004804Recruiting
Video group therapy for chronic pain in older Veterans
This study tests whether group therapy sessions held over video can help older Veterans manage chronic muscle or joint pain. It focuses on teaching practical skills to reduce pain and improve quality of life.
West Los Angeles, CaliforniaAges 60–95 - NCT06478628Enrolling by invitation
Insomnia in pain rehabilitation patients
This trial looks at sleep problems in people going through pain rehabilitation. It aims to understand and possibly improve sleep in those with long-lasting pain.
RissaAges 18 years+ - NCT07494734Enrolling by invitation
Manual therapy for neck pain, disability, and quality of life
This study tests whether manual therapy (hands-on techniques) can reduce neck pain, improve daily function, and enhance quality of life for people with long-term neck pain.
Kocaeli, GebzeAges 18–65
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Common questions
- Are there clinical trials for musculoskeletal pain?
- Yes. Clin2 currently lists 101 recruiting musculoskeletal pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.