Clinical trials
Musculoskeletal Pain clinical trials
Below are recruiting musculoskeletal pain clinical trials, each written for real people, not researchers. We’re tracking 93 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06500780Recruiting
Pain and depression support for African Americans
This study tests a program that helps people with both long-term pain and depression. It includes coaching and support to help you feel better and manage your health. The study is for Black or African American adults.
Indianapolis, IndianaAges 18 years+ - NCT06119698Recruiting
Improving Health for Older Adults With Pain Through Engagement
This study tests a program to help older adults with long-lasting bone, joint, or muscle pain become more active. Participants wear a smartwatch and get support to manage their pain and improve their health.
Boston, MassachusettsAges 55 years+ - NCT07173335Recruiting
Healthy lifestyle and pain care for rural residents
This trial tests a program that combines healthy lifestyle coaching with pain management for people living in rural areas who have chronic joint or back pain. It aims to help you feel better and move easier by addressing both pain and habits like diet, exercise, sleep, and smoking.
Coffs Harbour, New South WalesAges 18 years+ - NCT06512727Recruiting
Pain management study for Black older adults with long-term joint pain
This study tests two different approaches to help Black adults aged 50–92 manage chronic muscle or joint pain in their hips, knees, lower back, or ankles. It aims to find which method works better to reduce pain and improve daily life.
Gainesville, FloridaAges 50–92 - NCT07008105Recruiting
One session therapy for chronic pain
This study tests whether a single 90-minute online session can help people with chronic pain feel better. If you live with ongoing pain and want to try a brief psychological approach without medication, you may be a good fit.
Chicago, IllinoisAges 18 years+ - NCT06870162Recruiting
Pain disengagement training: a writing study for chronic pain
This study tests a writing-based program to help people with chronic pain learn to disengage from pain-related thoughts. It aims to reduce pain catastrophizing and improve daily function.
Boston, MassachusettsAges 18 years+ - NCT06297447Recruiting
Keeping it Simple: rehab for chronic pain
This study looks at how to better help people with ongoing muscle or joint pain who are getting rehabilitation through their local municipality. The goal is to learn what works best for you.
Holbæk, Region SjællandAges 18 years+ - NCT07685418Recruiting
Pressure therapy and home exercises for neck pain
This trial tests whether a hands-on technique called ischemic compression (applying gentle pressure to trigger points) plus home exercises helps relieve long-term neck pain that has no specific medical cause.
Istanbul, BakırköyAges 17–65 - NCT06886906Recruiting
Movement and Pain in Older Adults
This study explores how movement and physical activity relate to pain in older adults with muscle or joint pain. It could help you understand your pain patterns and find better ways to manage them.
Indianapolis, IndianaAges 55–85 - NCT07331766Enrolling by invitation
Collaborative care for chronic pain patients
This trial tests a team-based treatment approach for people with chronic pain. You'll work with at least two pain clinic specialists to create a care plan that fits your needs.
Ottestad, InnlandetAges 18 years+ - NCT07602595Recruiting
Early-life health risks and chronic pain in teens and young adults
This study looks at how early health problems might affect pain that lasts a long time. If you had a muscle or joint surgery, or a rheumatic disease, before age 18, you might help us understand why some people get ongoing pain.
Cincinnati, OhioAges 14–26 - NCT07218757Recruiting
Trial of emotional awareness therapy for veterans with chronic pain
This study tests if a type of therapy that helps you understand and express emotions related to pain (called Emotional Awareness and Expression Therapy) can reduce chronic pain in veterans. It is designed for veterans who have had muscle or joint pain for at least 3 months and rate their pain as moderate or greater.
Los Angeles, CaliforniaAges 18 years+ - NCT07048366Recruiting
Mindfulness in a museum for fibromyalgia pain relief
This study tests whether a mindfulness program held in a museum setting can help women with fibromyalgia feel less pain and improve their quality of life. You would attend sessions in a museum and practice mindfulness techniques.
Chieti, AbruzzoAges 18–60 - NCT07193095Recruiting
Comparing two brief pain relief programs for chronic pain
This study compares two brief programs (mindfulness skills vs. pain relief education) to see which helps adults with chronic muscle or joint pain feel better. You would attend one or two sessions and complete short questionnaires, all from home.
Tallahassee, FloridaAges 18 years+ - NCT07486505Recruiting
Mindfulness for pain after arm or leg fracture surgery
This study tests whether brief mindfulness sessions before and after surgery help people manage pain and anxiety while recovering from a broken arm or leg, and may reduce the need for strong painkillers (opioids). It aims to see if this approach is practical and helpful for patients.
Hamilton, OntarioAges 18 years+ - NCT07605013Recruiting
Neck Exercises for Office Workers: Building Strength and Function
This study tests whether specific neck mobilization techniques (gentle movements and stretches) can improve neck strength and function in desk workers. You would be a healthy control participant to help researchers understand how these techniques work in people without existing neck pain.
IstanbulAges 18–40 - NCT07827677Recruiting
Brain stimulation for muscle pain relief in people with insomnia
This study looks at whether different types of brain stimulation (called TMS) can help reduce the muscle pain triggered during a test. It is designed for people who also have insomnia, and who are otherwise healthy.
Hong KongAges 18–60 - NCT06478628Enrolling by invitation
Insomnia in pain rehabilitation patients
This trial looks at sleep problems in people going through pain rehabilitation. It aims to understand and possibly improve sleep in those with long-lasting pain.
RissaAges 18 years+ - NCT06004804Recruiting
Psychological treatments for chronic pain in veterans
This study compares two group psychological treatments for chronic pain delivered over video conference. It aims to see if these treatments help reduce pain and improve quality of life for veterans.
West Los Angeles, CaliforniaAges 60–95 - NCT05555576Recruiting
Vitamin C to reduce opioid use after an ER visit
This trial tests whether taking vitamin C after an emergency room visit for a new, short-term muscle or joint pain can lower how many opioid pain pills you use. It may help by reducing opioid consumption while you recover.
Montreal, QuebecAges 18 years+ - NCT07637552Enrolling by invitation
Deep vs. Shallow Needle Treatment for Neck Pain
This study compares two ways of using dry needling (a technique where thin needles are inserted into tight muscles) to treat neck pain caused by muscle knots. Researchers will use ultrasound and electrical testing to see which approach works better and is safer.
Dammam, Eastern ProvinceAges 18–65 - NCT07494734Enrolling by invitation
Manual therapy for neck pain, disability, and quality of life
This study tests whether manual therapy (hands-on techniques) can reduce neck pain, improve daily function, and enhance quality of life for people with long-term neck pain.
Kocaeli, GebzeAges 18–65 - NCT06283199Recruiting
Tracking pain reports with a smartphone app
This trial compares pain reports recorded in real time using a smartphone app to those collected during monthly clinic visits. It aims to understand if daily tracking gives a more accurate picture of symptoms for people with musculoskeletal conditions.
BolognaAges 18 years+ - NCT06671860Recruiting
Exercises and hands-on therapy for neck pain
This study tests whether combining eye exercises with hands-on therapy helps people with non-specific neck pain (pain not caused by a known injury or disease). It may help improve how your neck moves and reduce discomfort.
IstanbulAges 18–65
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Common questions
- Are there clinical trials for musculoskeletal pain?
- Yes. Clin2 currently lists 93 recruiting musculoskeletal pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.