Clinical trials
Musculoskeletal clinical trials
Below are recruiting musculoskeletal clinical trials, each written for real people, not researchers. We’re tracking 207 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05701982Recruiting
Walking plus Tai Chi coach via video for COPD and pain
This study tests whether a phone/computer program that combines walking training with Tai Chi improves physical function (how well you move) in people who have COPD and long-term body or muscle pain. It may help you build strength, balance, and safer movement—especially if pain makes activity hard.
Boston, MassachusettsAges 40–100 - NCT05417685Enrolling by invitation
Digital physical therapy for musculoskeletal pain
This trial studies a smartphone/tablet-based care program to help people with neck, back, shoulder, elbow, wrist/hand, hip, knee, or ankle pain. It may help reduce pain and improve function using guided exercises, as long as it is safe for you to do light-to-moderate activity.
Draper, UtahAges 18 years+ - NCT04800484Recruiting
Test how different AFO heel height and stiffness affect walking
This study looks at how changing the heel height and stiffness of an AFO (a brace you wear on your lower leg/foot) changes your walking pattern. The goal is to learn which brace settings may improve comfort and walking.
Iowa City, IowaAges 18–70 - NCT07602595Recruiting
Early-life health risks and chronic pain in teens and young adults
This study looks at how early health problems might affect pain that lasts a long time. If you had a muscle or joint surgery, or a rheumatic disease, before age 18, you might help us understand why some people get ongoing pain.
Cincinnati, OhioAges 14–26 - NCT06685107Recruiting
Virtual reality for pain relief in older ER patients
This trial tests if using virtual reality along with standard pain medication helps reduce pain better than medication alone for older adults with muscle or joint pain in the emergency room.
Brooklyn, New YorkAges 65–120 - NCT06886906Recruiting
Movement and Pain in Older Adults
This study explores how movement and physical activity relate to pain in older adults with muscle or joint pain. It could help you understand your pain patterns and find better ways to manage them.
Indianapolis, IndianaAges 55–85 - NCT04394052Recruiting
Imaging tests for suspected bone or soft-tissue tumors
This trial studies new imaging methods to better identify and stage (find how far it has spread) suspected bone or soft-tissue tumors. It may help your care team choose the most accurate next steps based on your scans.
Nancy, LorraineAges 18 years+ - NCT04684602RecruitingPhase 1/Phase 2
Study of stem cells for several short- and long-term illnesses
This early-stage study tests whether injections of mesenchymal stem cells can be safe and helpful for certain chronic (long-term) and acute (short-term) conditions. You might be considered if you can consent, are able to return for follow-up visits, and do not have key reasons that would make stem-cell treatment unsafe.
Culver City, CaliforniaAges 18 years+ - NCT05440240RecruitingPhase 4
Needling and possibly steroid shot for Dupuytren’s hand tightness
This trial tests a minimally invasive procedure that uses a needle to release tight tissue in the hand, and may include a steroid injection. It aims to improve hand finger straightening for people with Dupuytren’s contracture.
SilkeborgAges 45–99 - NCT07857798Recruiting
How your body traits relate to growth and development
This study looks at how different physical traits, like height and body shape, relate to growth and development. By participating, you'll help researchers understand normal human variation, which may improve future health care.
Guangzhou, GuangdongAges 18–60 - NCT05110729Recruiting
Check how injuries affect quality of life in young gymnasts
This study looks at how musculoskeletal injuries change quality of life and life satisfaction for gymnasts ages 8 to 18. It may help sports medicine teams understand what young gymnasts need to feel better and keep doing their sport.
Denver, ColoradoAges 8–18 - NCT07850830Recruiting
Virtual reality rehab survey for arm and shoulder conditions
This study asks people using virtual reality for arm or shoulder rehabilitation to answer questions about how they feel about it. Your responses help improve VR rehab for conditions like shoulder pain or stroke recovery.
CairoAges 20–50 - NCT06409962Recruiting
New school program for childhood obesity and prediabetes
This study tests a new program to help children with obesity, focusing on those with slightly higher blood sugar (prediabetes). It takes place at a school and requires both parent and child consent.
CórdobaAges 6–16 - NCT07827664Recruiting
How insomnia affects muscle pain from exercise
This study looks at how insomnia affects pain sensitivity and how much muscle pain people feel after exercise. It may help researchers understand the link between sleep and pain, which could lead to better treatments for people with insomnia.
Hong KongAges 18–60 - NCT07827677Recruiting
Brain stimulation for muscle pain relief in people with insomnia
This study looks at whether different types of brain stimulation (called TMS) can help reduce the muscle pain triggered during a test. It is designed for people who also have insomnia, and who are otherwise healthy.
Hong KongAges 18–60 - NCT07826650Recruiting
How acute pain affects sleep in people with insomnia
This study looks at how a short-term (acute) pain affects sleep quality in people who suffer from insomnia compared to healthy sleepers. Participation may help researchers understand the link between pain and sleep problems.
Hong KongAges 18–60 - NCT07813429Recruiting
Neck posture and pain changes after sleeve gastrectomy
This study looks at how weight-loss surgery (sleeve gastrectomy) may affect the position of your neck, how well your neck moves, and any neck pain you might have. You will be followed for a year to see if losing weight helps improve your neck health.
Istanbul, IstanbulAges 18–65 - NCT06395428RecruitingPhase 4
Haloperidol for severe back pain in the ER
This study tests whether the medication haloperidol, given in the emergency room, can help relieve severe back pain that started on its own (not from an injury). It compares haloperidol to a common pain reliever called ketorolac.
Kalamazoo, MichiganAges 18–65 - NCT07808619Recruiting
AI health data study for adults
This study is collecting health data to train an AI system that may help predict or improve health outcomes. By joining, you help develop technology that could benefit patients in the future.
Boulder, ColoradoAges 18 years+ - NCT06516172Recruiting
The Bern Rehabilitation Registry for Chronic Conditions
This trial is creating a registry to study how people with chronic diseases benefit from rehabilitation programs. If you are an adult with a long-term health condition and have been referred to rehab, your data could help improve care for others.
Heiligenschwendi, Canton of BernAges 18 years+ - NCT05752396Recruiting
Study of Pain Patterns Over Time in Kids
This study follows kids who have a specific type of chronic pain (headaches, stomach pain, or muscle/joint pain) to better understand how pain changes over time. It also checks whether certain factors are linked to those pain patterns.
Cincinnati, OhioAges 10–19 - NCT05610098Recruiting
Study of gene activity in spinal tuberculosis
This trial looks at patterns of gene activity (from blood/tissue samples) in adults with spinal tuberculosis. The goal is to better understand the disease and how to tell different conditions apart, which may help future care.
Cape Town, Western CapeAges 18 years+ - NCT07753291Recruiting
Yi Jin Jing exercise for muscle and bone health in adults
This study looks at whether a special exercise routine called Yi Jin Jing (a type of traditional Chinese exercise) can help improve muscle and bone health in adults. It might be good for you if you are mostly healthy and want to try a gentle exercise program.
BeijingAges 18–90 - NCT07756229Recruiting
Physiotherapy for long-term neck pain
This study looks at how physiotherapy affects brain activity and symptoms in people with chronic neck pain lasting more than 3 months. It aims to see if physiotherapy can help reduce pain and improve function.
San Sebastián, GuipuzcoaAges 18 years+
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Common questions
- Are there clinical trials for musculoskeletal?
- Yes. Clin2 currently lists 207 recruiting musculoskeletal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.