Clinical trials
Neurology clinical trials
Below are recruiting neurology clinical trials, each written for real people, not researchers. We’re tracking 375 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03922555RecruitingPhase 1
ASTX727 for IDH-mutant low-grade brain tumors
This early-stage study tests ASTX727 in adults with IDH-mutant gliomas that are coming back or progressing. It aims to see whether the medicine can slow the tumor and understand how it works in the body and tumor tissue.
Boston, MassachusettsAges 18 years+ - NCT02879123Recruiting
Recovery after stroke treatment with a clot-removal procedure
This trial studies how the brain and nervous system recover about 3 months after a clot-removal treatment for an acute ischemic stroke. It may help doctors better understand what recovery looks like after this kind of stroke care.
ParisAges Any age - NCT03777267Recruiting
Test a brain-sensing device for stress, anxiety, or insomnia
This exploratory study tests how a wearable brain-sensing setup (with sensor leads/earbuds) works for people with stress, anxiety, or sleep problems. You may be asked to sit still during sessions and complete brief questionnaires to confirm your symptoms.
Winston-Salem, North CarolinaAges 11 years+ - NCT03678389Recruiting
Check feasibility of a coil for pituitary surgery imaging
This trial tests whether a special coil can be placed during pituitary tumor surgery to improve imaging while the surgeon is operating. It may help surgeons see the pituitary area in real time during a transsphenoidal (through the nose) operation.
Bethesda, MarylandAges 18–85 - NCT03478852Recruiting
Epilepsy screening and evaluation for people 8 and older
This study checks how people with known or suspected epilepsy are evaluated and followed. It may help by improving screening and understanding care for epilepsy in children and adults.
Bethesda, MarylandAges 8–110 - NCT02649985RecruitingPhase 1/Phase 2
PET brain scan study for several brain and mood conditions
This early-phase study uses PET and MRI brain scans to better understand brain changes in multiple sclerosis, Alzheimer’s disease, and other neurological or mood conditions. The goal is to test whether these scans can show disease-related differences and guide future treatments.
Boston, MassachusettsAges 18–85 - NCT03225144Recruiting
Study of gene and disease changes in ALS and frontotemporal dementia
This study looks at complex brain and body changes in people with ALS and frontotemporal dementia (FTD), or related disorders. If you have one of these diagnoses—or a known gene mutation that can cause ALS/FTD—you may be able to help researchers learn how the conditions progress.
Bethesda, MarylandAges 18–110 - NCT03288220Recruiting
Brain stimulation trial to improve arm movement
This trial studies whether a specific kind of non-painful brain stimulation (TMS) can improve arm and hand movement. It tests this in healthy volunteers and in people recovering from stroke.
Bethesda, MarylandAges 18–120 - NCT03026816Recruiting
Epidural stimulation to improve function after spinal cord injury
This study tests whether stimulating the nerves in your spine (via an epidural device) can improve rehab-related function after a spinal cord injury. It focuses on people with stable, motor-complete paraplegia and long-term injuries, and it compares how you respond to the stimulation during rehabilitation.
Minneapolis, MinnesotaAges 22 years+ - NCT03232463Enrolling by invitation
Testing an advanced MRI scan in everyday clinic care
This study checks whether a more advanced MRI scan can be safely used in regular clinical practice. If you need an MRI for a health problem, the study may help your care team use the newer scan approach.
Santa Monica, CaliforniaAges 18–65 - NCT02784210RecruitingPhase 2
Steroid treatment to reduce inflammation in active MS lesions
This Phase 2 study tests whether corticosteroid medicine can reduce inflammation at the edge of active multiple sclerosis (MS) plaques seen on MRI. It may help calm “hot” areas in the brain where MS activity is happening.
Bethesda, MarylandAges 18–120 - NCT02576925Recruiting
Predicting the cause of brief double vision episodes
This trial looks at a way to predict what causes short-lasting double vision. It may help doctors choose the right next steps faster after symptoms stop.
ParisAges 18 years+ - NCT02531880RecruitingPhase 1
MRI test of a brain barrier issue in hard-to-treat epilepsy
This early-phase study uses a special MRI approach to look for signs that the “blood-brain barrier” is breaking down in people with drug-resistant epilepsy. It may help researchers understand what is happening in the brain and guide future treatments, though it is primarily a testing/study study.
Bethesda, MarylandAges 18–60 - NCT02639325Recruiting
Seizure treatment study for people with brain tumors
This study looks at how a brain tumor-related seizure condition is handled in children and adults. It may be a good option if your seizures started soon after your brain tumor was found or is in the same brain area as your seizure symptoms.
Bethesda, MarylandAges 8–99 - NCT02659956Recruiting
Study brain and eye changes on MRI in MS
This study looks at how multiple sclerosis (MS) affects MRI scans and other measurements in the brain, spinal cord, and eyes. It may help researchers better understand MS changes over time, using follow-up visits and, in the future, donated tissue after death.
Bethesda, MarylandAges 18–120 - NCT02629107Recruiting
Sleep and brain scan study with sound cues
This study checks how your brain responds while you sleep using an MRI scanner and gentle sound signals. It may help researchers better understand sleep and brain function.
Bethesda, MarylandAges 18–34 - NCT02435810Recruiting
Study of infections and inflammation affecting the nervous system
This study looks at how infections or inflammation involving the brain and spinal cord work, using patient data and samples. It may help researchers better understand these illnesses and improve future care.
Bethesda, MarylandAges 2–110 - NCT02260271Enrolling by invitation
Study for newborns with severe oxygen-related brain injury
This trial is for newborn babies who had an oxygen shortage around birth and now have severe brain injury. It aims to test approaches that may help improve outcomes after this kind of early-life brain damage.
Gainesville, FloridaAges 1 day–3 weeks - NCT02382601Recruiting
Study of pregnancies with slow fetal growth
This study follows pregnancies where the baby appears smaller than expected on ultrasound. It may help researchers better understand why this happens and how to monitor care over time.
Aurora, ColoradoAges 18–45 - NCT02670161Enrolling by invitationPhase 4
Using electronic records to improve care for brain and nerve conditions
This study looks at how doctors use electronic medical records to improve treatment and care for people with certain brain and nervous system conditions. It may help because it tests practice-based approaches across neurology visits.
Evanston, IllinoisAges 18–100 - NCT02621944RecruitingEarly Phase 1
Melatonin for newborns with brain injury after oxygen problems
This early study tests whether giving melatonin to newborns with hypoxic-ischemic encephalopathy (brain injury from not enough oxygen around birth) can help protect the brain while they are cooled (therapeutic hypothermia). It may be most relevant if your baby shows early brain-injury signs and meets specific blood test and birth-history timing criteria.
Gainesville, FloridaAges Up to 6 hours - NCT02119611Recruiting
Deep brain stimulation for Parkinson’s, dystonia, or tremor
This study tests deep brain stimulation (DBS), a therapy that sends electrical signals to the brain, for movement problems like Parkinson’s disease, dystonia, and essential tremor. It may help people whose symptoms are not controlled enough with medications, or who already have a DBS device and need ongoing management.
Bethesda, MarylandAges 18–100 - NCT01875588Recruiting
Long-term study of thinking and memory in adults with HIV
This study looks at how thinking and memory change over time in adults with HIV and compares them with adults without HIV. Researchers will do regular visits and brain/cognitive testing to understand what affects thinking and memory and to learn what might help.
Bethesda, MarylandAges 18–110 - NCT01730131Recruiting
Study of PML in patients, at-risk people, and healthy volunteers
This study follows people with suspected or confirmed progressive multifocal leukoencephalopathy (PML), people at higher risk, and healthy volunteers. It uses visits, brain imaging (MRI), and stored biological samples to better understand how PML progresses and who is at risk.
Bethesda, MarylandAges 2–120
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Common questions
- Are there clinical trials for neurology?
- Yes. Clin2 currently lists 375 recruiting neurology studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neurology trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neurology trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.