Clinical trials
Noninvasive Ventilation clinical trials
Below are recruiting noninvasive ventilation clinical trials, each written for real people, not researchers. We’re tracking 19 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07298889Recruiting
Higher pressure support for pneumonia or ARDS patients
This trial tests whether using a higher level of pressure support (called PEEP) during noninvasive mask breathing can help people with pneumonia or ARDS (a serious lung condition) recover. It might be a good option if you need help breathing with a mask and meet the oxygen level requirements.
ChongqingAges 18 years+ - NCT06483984Recruiting
Testing facemasks to remove carbon dioxide in breathing trouble
This trial tests special facemasks that help remove carbon dioxide from the blood during noninvasive breathing support (like a CPAP or BiPAP mask). It is for people who have a sudden breathing problem with high carbon dioxide and low blood pH.
RomaAges 18 years+ - NCT06795971Recruiting
Comparing oxygen methods for hypoxemic respiratory failure
This trial compares three ways of giving extra oxygen to people with low blood oxygen levels: a face mask with continuous pressure, a noninvasive ventilator, or high-flow oxygen through the nose. The goal is to see which method helps people avoid needing a breathing tube.
Nanjing, JiangsuAges 18 years+ - NCT05336136Recruiting
Custom breathing-mask fit testing for children
This trial studies whether a custom, non-invasive breathing mask works better or is easier for children to use. It’s meant to improve comfort and fit while supporting breathing therapy without invasive procedures.
Edmonton, AlbertaAges 8–12 - NCT07237139Recruiting
Lung volume changes during breathing support in preterm infants
This study measures how the lungs of preterm babies (born before 30 weeks) expand during synchronized breathing support. It aims to understand how well this ventilator method works for very young infants.
Zurich, Canton of ZurichAges Up to 4 weeks - NCT07211906Enrolling by invitation
Oral care education for home ventilator users
This study tests whether a simple oral care education program, delivered through the LINE app, can improve mouth health and quality of life for people who use a non-invasive breathing machine at home.
Chiayi City, TaiwanAges 18 years+ - NCT06837402Enrolling by invitation
Non-invasive ventilation in Argentine ICUs: an observational study
This study looks at how non-invasive breathing support (like a mask or machine) is used in ICUs across Argentina. It helps doctors understand patterns of care so they can improve treatment for patients with breathing problems.
CABA, Buenos AiresAges 18 years+ - NCT05756387Recruiting
Improving nighttime home breathing support for people with COPD
This study tests different ways to improve chronic noninvasive nighttime breathing support at home for people with COPD. It may help make home treatment easier and more effective, using better tools and setup.
GroningenAges Any age - NCT05918575Recruiting
Breathing support after a breathing tube in very obese adults
This trial tests whether giving noninvasive breathing support (using a mask or similar device, without a new breathing tube) right after removing a breathing tube works better for severely obese adults. It mainly looks at people at higher risk of needing help breathing again after extubation.
Chicago, IllinoisAges 18 years+ - NCT03758508Recruiting
Noninvasive breathing support versus high-flow oxygen for pneumonia
This study compares two ways to help breathing in adults with pneumonia who have low oxygen levels: a noninvasive breathing machine versus high-flow oxygen. It aims to see which option helps patients breathe better and avoid getting worse.
MilanAges 18 years+ - NCT04136717Recruiting
Test if FreeO2 helps keep oxygen levels in range
This study looks at whether adding FreeO2 can help keep your oxygen saturation (a measure of oxygen in the blood) within a target range while you use breathing support like NIV or CPAP. It may help reduce time spent either too low or too high in oxygen levels.
Québec, QuebecAges 18 years+ - NCT06671015Recruiting
Comparing breathing support methods after a breathing tube is removed in people with heart failure
This study compares two types of breathing support—a high-flow nasal cannula and noninvasive ventilation—to see which one better prevents the need for re-inserting a breathing tube in people with systolic heart failure who are at high risk for breathing problems after the tube is removed.
New Haven, ConnecticutAges 18 years+ - NCT07503509Recruiting
Study of high PEEP in noninvasive ventilation
This study tests whether using higher pressure settings (PEEP) on a noninvasive breathing mask can help people with low oxygen levels. The doctors will measure the pressure inside your esophagus to guide the treatment.
Chongqing, Chongqing MunicipalityAges 18–100 - NCT05513508Recruiting
Tested a protective breathing mask in COPD and respiratory failure
This study tests how well a specific breathing mask setup works in people who need noninvasive ventilation (breathing support without a breathing tube), especially during COPD flare-ups or certain kinds of breathing failure. It may help reduce complications related to the mask while supporting breathing for at least a day.
NovaraAges 18 years+ - NCT05881031Recruiting
Home breathing support for medically complex children
This trial studies whether starting a noninvasive breathing machine (given without a tube in the airway) at home works well and is tolerated in children with medical complexity. It may help improve comfort and safety when new breathing support is prescribed.
Toronto, OntarioAges 5 years–17.9 years - NCT06171035Recruiting
3D-printed manikin for teaching breathing support
This study tests whether a 3D-printed face model helps teach medical students how to use noninvasive ventilation (a breathing mask). It may make training more realistic and effective.
New Taipei CityAges 18–30 - NCT07750288Recruiting
Understanding breathing difficulty in children with lung injury
This study looks at how severe breathing difficulty (dyspnea) affects the recovery of children with a lung condition called acute respiratory distress syndrome (ARDS). It aims to improve care by tracking symptoms over time.
SantiagoAges 1 month–18 years - NCT06996509Recruiting
Noninvasive breathing support for Guillain-Barré syndrome
This trial tests whether noninvasive breathing support (like a mask or nasal prongs) can help people with Guillain-Barré syndrome who have trouble breathing. It aims to see if this approach can avoid the need for a breathing tube.
Asyut, AssuitAges 18 years+ - NCT06996834Recruiting
Comparing breathing support methods for pneumonia-related breathing failure
This trial tests two noninvasive breathing support methods (NIV and HVNI) for people with pneumonia who are having trouble breathing. The goal is to see which method works better to help you avoid needing a breathing tube.
Asyut, AssuitAges 18 years+
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Common questions
- Are there clinical trials for noninvasive ventilation?
- Yes. Clin2 currently lists 19 recruiting noninvasive ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a noninvasive ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a noninvasive ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.