Clinical trials · California
Obesity clinical trials in California
We’re tracking 118 recruiting obesity studies with a site in California — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06937086RecruitingPhase 3
Mirikizumab plus tirzepatide for UC with obesity
This study tests whether adding mirikizumab to the weight-loss drug tirzepatide helps people with moderate-to-severe ulcerative colitis who also have obesity or overweight. It aims to see if the combination reduces bowel inflammation and helps with weight management.
Anaheim, CaliforniaAges 18–70 - NCT06937099RecruitingPhase 3
Testing two drugs for Crohn's with weight issues
This trial tests two study drugs, mirikizumab and tirzepatide, in people with moderate to severe Crohn's disease who also have overweight or obesity. The goal is to see if these treatments can help control Crohn's symptoms and inflammation.
Anaheim, CaliforniaAges 18–70 - NCT06857942RecruitingPhase 4
Tirzepatide added to ixekizumab for psoriasis and weight issues
This trial tests whether adding tirzepatide (a weight-loss and diabetes drug) to ixekizumab (a psoriasis treatment) helps people with moderate-to-severe psoriasis who are overweight or have obesity. It is for those already taking ixekizumab for about 3 months.
Fountain Valley, CaliforniaAges 18 years+ - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Oxnard, CaliforniaAges 12–17 - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Loma Linda, CaliforniaAges 6–17 - NCT05143697Recruiting
Coaching program to help young children reduce excess weight
This trial tests a family wellness coaching program using motivational interview counseling and referrals. It may help families support healthier habits for children ages 2 to 8 who have weight above a recommended range.
Pasadena, CaliforniaAges 2–8 - NCT06439277RecruitingPhase 3
Tirzepatide for teens with obesity and related health problems
This study tests a medication called tirzepatide (a once-weekly injection) to help teenagers with obesity and related health conditions lose weight. It aims to see if the drug is safe and effective for this age group.
Sacramento, CaliforniaAges 12–17 - NCT06398509Recruiting
Preventing obesity in Latino babies at checkups
This study tests a program that helps prevent childhood obesity in low-income Latino families. It takes place during your baby's regular checkups and offers extra support for healthy feeding and growth.
San Francisco, CaliforniaAges 1 week–2 months - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
Greenbrae, CaliforniaAges 18–75 - NCT06067763Enrolling by invitation
Project Health: Preventing unhealthy weight gain in young adults
This study tests a program to help young adults improve their eating and exercise habits, with the goal of preventing obesity. It is designed for people who are concerned about their weight and want to make healthier lifestyle choices.
Stanford, CaliforniaAges 17–20 - NCT05726942Recruiting
Using a weight-management mobile app for adults with extra weight
This trial studies whether a mobile phone app can help people manage weight. It may help you if you have overweight or obesity and are able to track your weight with a bathroom scale.
San Diego, CaliforniaAges 18–64 - NCT05215886Enrolling by invitation
Bariatric surgery and memory problems in people with obesity
This study looks at how bariatric (weight-loss) surgery may affect memory and thinking in people with obesity who already have memory decline or dementia. It may help doctors understand which patients benefit most and what changes to expect.
Sacramento, CaliforniaAges 18–75 - NCT03022682Recruiting
Study of inflammation and metabolism across diabetes and weight
This is an observational study that follows generally healthy adults to understand how inflammation, diabetes (type 2), and weight/metabolic health relate to each other. It may help researchers figure out why different groups (including different ethnic backgrounds) have different health risks.
San Francisco, CaliforniaAges 18–75 - NCT07837973RecruitingPhase 2
Medicine to maintain weight loss after weight-loss shots
This study tests a new medicine called ALV-100 to see if it can help people who have already lost weight with a weight-loss injection or pill keep the weight off. You must be currently on a stable weight-loss medicine and have lost at least 10% of your body weight to join.
Oceanside, CaliforniaAges 18–75 - NCT07839832Recruiting
Healthy goals study for teens with obesity
This study looks at healthy lifestyle programs for children ages 10-15 who are overweight. You and your child will be involved together in activities to help improve health.
Stanford, CaliforniaAges 10–15 - NCT05197738Recruiting
Study using a sleep health app to improve sleep
This study tests a “sleep health” app (REFRESH) to see how it may help people track and improve sleep. You may be eligible if you’re an adult in the U.S. who can use the app on your own phone.
La Jolla, CaliforniaAges 18 years+ - NCT07815678RecruitingPhase 1/Phase 2
Safety study of an oral medication in people with normal or higher weight
This study tests a new oral medication called ACCG-2671 to see how safe it is and how your body handles it. It's an early-stage trial, so the main focus is on safety and tolerability. The study has different parts: one for people with normal weight and one for people with higher weight who are already taking a GLP-1 injection for weight loss.
Cypress, CaliforniaAges 25–75 - NCT07806838Recruiting
Dietary supplements to preserve muscle during GLP-1 weight loss
This study looks at whether certain dietary supplements can help preserve muscle mass while you are taking a GLP-1 medication for weight loss. You would take the supplements or a placebo for a period while continuing your GLP-1 treatment, and the researchers will measure changes in your muscle and strength.
Los Angeles, CaliforniaAges 18 years+ - NCT07792837Recruiting
Online intuitive eating program for pregnant women with obesity
This study tests an online program that helps pregnant women with obesity learn to eat intuitively, which means listening to their body's hunger and fullness signals instead of dieting. The goal is to support their well-being during pregnancy.
San Diego, CaliforniaAges 18 years+ - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Glendora, CaliforniaAges 18 years+ - NCT07770841RecruitingPhase 3
Oral medication for weight loss study
This study tests an oral medicine (semaglutide) to see if it helps adults with excess weight lose weight. It might offer an easier, pill-based treatment option for weight management.
Huntington Park, CaliforniaAges 18 years+ - NCT07720271RecruitingPhase 3
Zenagamtide weight loss study for adults
This study is testing a new tablet called Zenagamtide to help people with extra body weight lose weight. It's for adults who are not diabetic and haven't used similar weight loss drugs before.
Walnut Creek, CaliforniaAges 18 years+ - NCT07710768RecruitingPhase 1
A study on how UBT251 affects certain drugs in people with extra weight
This study tests if a new medicine called UBT251 changes how the body processes caffeine, midazolam (a sedative), and warfarin (a blood thinner). It is for generally healthy adults with a Body Mass Index (BMI) between 27 and 40.
Cypress, CaliforniaAges 18–65 - NCT07684235RecruitingPhase 3
Long-term study of a weight-loss drug for trial graduates
This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.
Fountain Valley, CaliforniaAges 18–99
Obesity trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting obesity studies listed above.
- Diablo Clinical Research · 3 studies
- California Medical Research Associates · 2 studies
- Carey Chronis MD Pediatric, Infant and Adolescent Medicine · 2 studies
- Cedars-Sinai Medical Center · 2 studies
- San Diego State University · 2 studies
- Smart Cures Clinical Research · 2 studies
- Stanford University · 2 studies
- United Medical Doctors · 2 studies
What taking part in a obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Obesity trials in other states
Common questions
- Are there obesity clinical trials in California?
- Yes. We're currently tracking 118 recruiting obesity studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.