Clinical trials · North Carolina
Obesity clinical trials in North Carolina
We’re tracking 69 recruiting obesity studies with a site in North Carolina — including Early Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT05674799Recruiting
Program to lower future obesity and diabetes risks
This trial tests a lifestyle and coaching program (NDPP-NextGen) to help reduce the chances of obesity and diabetes risk passing to the next generation. It’s for people planning a pregnancy soon and who may be at higher risk due to body weight.
Winston-Salem, North CarolinaAges 18–39 - NCT05945355Recruiting
Study of breathing training for children with asthma
This study looks at how an asthma-specific breathing training program affects children’s breathing and asthma control. It may help your care team understand who could benefit from inspiratory (breathing-in) training.
Durham, North CarolinaAges 6–17 - NCT06116422Recruiting
Food Insecurity Program for Healthy Baby Weight
This study tests a program to help families with food insecurity and early signs of obesity in infants. It aims to learn the best ways to support healthy weight in babies at risk for overweight.
Durham, North CarolinaAges 1–2 - NCT07639021RecruitingPhase 2
Testing Different Dose Schedules of a New Weight Loss Medicine
This study tests a new injectable medication (NNC0662-0419) designed to help people with obesity lose weight. Researchers are comparing different ways of increasing the dose to find the safest and most effective approach.
Wilmington, North CarolinaAges 18 years+ - NCT06545435Recruiting
Study on body composition using BIA in adults with obesity
This trial uses a simple test called bioelectrical impedance analysis (BIA) to estimate muscle and fat in adults with obesity, comparing it to a more precise scan (DXA). It aims to see if BIA can reliably measure body composition.
Chapel Hill, North CarolinaAges 18 years+ - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
Greensboro, North CarolinaAges 18–75 - NCT06857942RecruitingPhase 4
Tirzepatide added to ixekizumab for psoriasis and weight issues
This trial tests whether adding tirzepatide (a weight-loss and diabetes drug) to ixekizumab (a psoriasis treatment) helps people with moderate-to-severe psoriasis who are overweight or have obesity. It is for those already taking ixekizumab for about 3 months.
Huntersville, North CarolinaAges 18 years+ - NCT06864026RecruitingPhase 4
Adding tirzepatide to ixekizumab for psoriatic arthritis with weight concerns
This study tests adding tirzepatide (a once-weekly injection for weight and diabetes) to your current treatment with ixekizumab for psoriatic arthritis. It may help with both joint symptoms and weight.
Salisbury, North CarolinaAges 18 years+ - NCT06991296Recruiting
Omega-3 supplement study for adults with obesity
This study looks at how omega-3 supplements affect certain fats in the blood of adults with obesity. Researchers want to see if taking these supplements changes these fats in a helpful way.
Kannapolis, North CarolinaAges 45–60 - NCT07065552RecruitingEarly Phase 1
Tirzepatide for weight-linked endometrial cancer
This trial tests if the weight-loss drug tirzepatide can help people with obesity-related endometrial cancer before their hysterectomy. It may improve surgical outcomes and overall health.
Chapel Hill, North CarolinaAges 18 years+ - NCT07216820Recruiting
Nerve blocks for shoulder surgery in obesity
This study compares two types of nerve blocks for shoulder surgery in people with obesity. It tests whether a block that spares the phrenic nerve (which helps you breathe) can keep your breathing strength stronger after surgery.
Chapel Hill, North CarolinaAges 18 years+ - NCT07037459RecruitingPhase 3
A study of a new drug for heart failure with obesity
This trial tests a medication called maridebart cafraglutide for people with heart failure (where the heart doesn't pump as well as it should) and obesity. The goal is to see if it can help improve symptoms and outcomes.
Durham, North CarolinaAges 18–99 - NCT07282600RecruitingPhase 3
Study of eloralintide for type 2 diabetes and weight
This study tests a new medicine called eloralintide for people with type 2 diabetes who are overweight or have obesity. It aims to see if the drug can help with weight loss and blood sugar control.
Greensboro, North CarolinaAges 18 years+ - NCT02583646Recruiting
Study how weight affects puberty in girls
This study looks at how a girl’s body weight may affect the start and development of puberty. It may help researchers understand what influences puberty timing and development in girls who are not yet having periods.
Research Triangle Park, North CarolinaAges 8–14 - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Greensboro, North CarolinaAges 18 years+ - NCT07570758RecruitingPhase 2
Testing ERX1000 to Help Adults Manage Obesity
This study tests whether a new medication called ERX1000 is safe and well-tolerated in adults with obesity. The trial will help doctors understand if this treatment could be helpful for weight management.
Monroe, North CarolinaAges 18–60 - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
Greensboro, North CarolinaAges 18–75 - NCT07156578Enrolling by invitationPhase 2
Long-term bivamelagon for hypothalamic obesity
This long-term study tests a new drug, bivamelagon, for people with hypothalamic obesity. It's for those who already completed a similar study and tolerated the drug well.
Chapel Hill, North CarolinaAges 12 years+ - NCT05082519RecruitingPhase 2
Calorie restriction and exercise to improve leukemia treatment in young patients
This study tests whether a special diet (calorie restriction) and increased physical activity can make chemotherapy work better for young people with B-ALL. Participants will follow a monitored diet and exercise plan during their first month of treatment.
Charlotte, North CarolinaAges 7–25 - NCT07526584Recruiting
Food Label Study in Indonesia
This study tests how different warning labels on packaged foods affect what people choose to buy in Indonesia. Researchers want to understand which label designs help people make healthier food choices.
Chapel Hill, North CarolinaAges 18 years+ - NCT06921382Recruiting
Breastfeeding help to prevent childhood obesity
This study offers breastfeeding support to new mothers to help prevent childhood obesity. It is for Hispanic mothers who plan to breastfeed and are eligible for WIC.
Greensboro, North CarolinaAges 5 days+ - NCT07153471RecruitingPhase 3
A study of an experimental pill for weight loss and knee arthritis
This trial tests an investigational medication (orforglipron) to see if it helps people with knee arthritis lose weight. You may qualify if you have overweight or obesity and have tried dieting before without lasting success.
Shelby, North CarolinaAges 18 years+ - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Greensboro, North CarolinaAges 18 years+ - NCT07225686RecruitingPhase 3
Maridebart Cafraglutide for sleep apnea in adults on CPAP
This study is testing whether a new medicine, called Maridebart Cafraglutide, can help people with obstructive sleep apnea who are already using a CPAP machine. The medicine may help with weight loss and potentially improve sleep apnea. Participants will either receive the medicine or a placebo (an inactive substance), and the study lasts for several months.
Monroe, North CarolinaAges 18–99
Obesity trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting obesity studies listed above.
- Monroe Biomedical Research · 4 studies
- Accellacare · 3 studies
- Lucas Research · 2 studies
- Lucas Research, Inc. · 2 studies
- Medication Management · 2 studies
- PharmQuest Life Sciences LLC · 2 studies
- Piedmont Healthcare · 2 studies
- University of North Carolina at Chapel Hill · 2 studies
What taking part in a obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Obesity trials in other states
Common questions
- Are there obesity clinical trials in North Carolina?
- Yes. We're currently tracking 69 recruiting obesity studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.