Clinical trials
Overweight or Obese clinical trials
Below are recruiting overweight or obese clinical trials, each written for real people, not researchers. We’re tracking 1,472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Birmingham, AlabamaAges 18 years+ - NCT07668414RecruitingPhase 3
Study comparing Zenagamtide and Semaglutide for weight loss
This trial tests a new medicine Zenagamtide to see if it helps people with excess weight lose more weight than Semaglutide, an existing weight loss drug. You may join if you are an adult with overweight or obesity but do not have diabetes.
Lancaster, CaliforniaAges 18 years+ - NCT07670884RecruitingPhase 3
Study of HRS9531 for weight loss in overweight or obese adults
This trial tests an oral medication, HRS9531, to help overweight or obese adults lose weight. It may be an option if you have been unable to lose enough weight through diet and exercise alone.
Zhengzhou, HenanAges 18–75 - NCT07656298Recruiting
Sweetener preference study for healthy adults
This study tests how different sweeteners affect your body if you have a sweet tooth. If you are generally healthy and like sweet foods or drinks, you may be able to join.
Málaga, MalagaAges 18–65 - NCT07652047RecruitingPhase 1
Safety Study of CX11 Tablets for Weight Management
This study tests whether a new medication called CX11 is safe and well-tolerated at different doses in people with overweight or obesity. The goal is to understand how the body responds to the drug before larger trials test whether it helps with weight loss.
Las Vegas, NevadaAges 18–55 - NCT07629544RecruitingPhase 3
Testing DA-302168S for weight loss in overweight and obese adults
This study tests a new medication called DA-302168S to help people lose weight. You may qualify if you're overweight or obese and meet certain health requirements.
BeijingAges 18–75 - NCT07631767Recruiting
Health Behavior Program for Night Shift Workers
This study tests a smartphone app designed to help night shift workers improve their sleep, eating habits, and overall health. You'll use the app to track and improve your wellness while working night shifts across Europe.
BremenAges 21 years+ - NCT07630597Recruiting
Ear Nerve Stimulation to Help Weight Loss
This trial tests a non-invasive device that gently stimulates a nerve in your ear to help you lose weight after lifestyle changes haven't worked well enough. You wear the device on your ear for 12 weeks while continuing healthy habits.
Nanjing, JiangsuAges 18–50 - NCT05840497Recruiting
Exercise program to help lower gestational diabetes risk
This trial tests whether a strength and resistance exercise program during pregnancy can help reduce gestational diabetes in people who are overweight or obese. It may help by improving how your body handles sugar during pregnancy.
Pamplona, NavarreAges 18 years+ - NCT07612527RecruitingPhase 2
Endoscopic Stomach Procedure for Weight Loss
This trial tests a minimally invasive procedure done through the mouth (no surgery) that reshapes the stomach to help with weight loss. It combines two techniques to reduce stomach function and may help people lose weight without traditional bariatric surgery.
CairoAges 18 years+ - NCT07619989Recruiting
Ear nerve stimulation for weight loss after tirzepatide
This trial tests if a gentle electrical stimulation to the ear can help people who haven't lost much weight with tirzepatide (a diabetes/weight drug). It's for people who are still overweight after 12 weeks of treatment.
Nanjing, JiangsuAges 18–50 - NCT07607587RecruitingPhase 1
Testing a new weight-loss drug for people who couldn't tolerate GLP-1 shots
This study tests a new injectable medication called cagrilintide for people with obesity who had to stop GLP-1 drugs (like Ozempic or Wegovy) because of stomach problems. The goal is to see if cagrilintide causes fewer stomach side effects while still helping with weight.
Walnut Creek, CaliforniaAges 18 years+ - NCT07599072Recruiting
Blood Sugar Monitoring Study for Prediabetes
This study tracks how blood sugar levels change in people with prediabetes (higher-than-normal blood sugar but not yet diabetes). Researchers will use a small sensor to monitor your blood sugar and help understand what affects it, which could help prevent or delay type 2 diabetes.
KyivAges 18 years+ - NCT07592728Recruiting
Brief training to help teens eat healthier
This trial tests a smartphone-based training program designed to help teens with overweight or obesity make better food choices. It may be a good fit if you're looking to improve your diet and are not currently in treatment for an eating disorder or weight loss.
Fairfax, VirginiaAges 14–17 - NCT07577765Recruiting
Keeping Weight Off With a Personalized Plan
This study tests a customized approach to help you maintain weight loss you've already achieved. Researchers will use your smartphone to send you tailored support and track your progress over time.
Salt Lake City, UtahAges 18–65 - NCT07583459Recruiting
Summer childcare program to prevent unhealthy weight gain in preschoolers
This study tests whether a center-based childcare program during summer can help prevent excessive weight gain in preschool-aged children from low-income families. The program focuses on healthy eating and activity habits during the summer months when children are not in school.
Columbia, South CarolinaAges 3–5 - NCT07571109RecruitingPhase 3
Weight Loss Medicine for Sleep Apnea on CPAP
This study tests a new injectable medicine (NNC0487-0111) to help people lose weight and improve obstructive sleep apnea (a breathing condition during sleep). You must already be using a CPAP machine (positive airway pressure device) for your sleep apnea.
Gilbert, ArizonaAges 18 years+ - NCT07571005RecruitingPhase 3
Testing a New Weight-Loss Medicine for Sleep Apnea
This study tests whether a new injectable medicine called NNC0487-0111 helps people with excess weight and moderate-to-severe obstructive sleep apnea (a condition where breathing stops repeatedly during sleep) lose weight and improve their sleep apnea—without needing a CPAP machine. The goal is to see if better weight loss can reduce sleep apnea symptoms.
San Diego, CaliforniaAges 18 years+ - NCT07573228Recruiting
Obesity's effect on insulin action and fitness in Type 1 Diabetes
This study examines how excess weight affects how insulin works in small blood vessels and overall fitness in people with Type 1 Diabetes. Researchers want to understand if obesity makes diabetes management harder and whether this knowledge can help future treatments.
Charlottesville, VirginiaAges 21–50 - NCT07566325Recruiting
Avocado and inflammation: can it improve your health?
This study tests whether eating avocado instead of refined carbohydrate foods (like white bread and sugary snacks) can reduce inflammation markers in your blood. If you have some signs of inflammation and extra weight around your middle, this might help researchers understand if avocado is a helpful dietary change.
Chicago, IllinoisAges 21–74 - NCT06151015Recruiting
Dietary nitrate and calorie restriction for brain health
This study tests whether eating foods rich in dietary nitrates (like beets) combined with reducing calorie intake improves memory and blood vessel function in older adults.
Nottingham, NottinghamshireAges 60–75 - NCT07539415RecruitingPhase 1
Safety and effectiveness study of new injection in healthy adults
This study tests a new experimental injection in healthy volunteers to see if it's safe and how well the body absorbs it. Researchers will compare it with other similar treatments to understand how it works.
SeoulAges 19–64 - NCT07533175RecruitingPhase 3
Testing a new weight-loss medicine for type 2 diabetes
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
Birmingham, AlabamaAges 18 years+ - NCT07519980Recruiting
Xanthigen supplement for weight and metabolism in young adults
This study tests whether a supplement called Xanthigen can help people aged 20–50 with mild overweight lose weight and improve their metabolism. You'll take the supplement and have your weight, blood work, and overall health monitored over time.
Murcia, MurciaAges 20–50
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Common questions
- Are there clinical trials for overweight or obese?
- Yes. Clin2 currently lists 1,472 recruiting overweight or obese studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.