Clinical trials
Overweight or Obese clinical trials
Below are recruiting overweight or obese clinical trials, each written for real people, not researchers. We’re tracking 1,472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Alexander City, AlabamaAges 18 years+ - NCT07554638RecruitingPhase 4
Incretin drugs for heart failure with obesity
This trial tests whether incretin-based diabetes medications (like GLP-1 drugs) can help people with a specific type of heart failure called HFpEF that is linked to obesity. The goal is to see if these drugs improve heart function and symptoms.
New York, New YorkAges 40 years+ - NCT07559227Recruiting
How obesity affects gut health and blood vessel function
This study compares people with normal weight to people with obesity who are otherwise healthy to understand how body weight affects gut bacteria, immune function, and blood vessel health. Results may help explain why some people with obesity stay healthier than others.
Muncie, IndianaAges 18–55 - NCT06323889Recruiting
Intermittent fasting study for adults with obesity
This study tests whether intermittent fasting (alternating periods of eating and fasting) can help with weight loss and health in adults with obesity. It aims to see if this approach is safe and effective.
Zurich, Canton of ZurichAges 18–50 - NCT07541677Recruiting
Muscle Loss and Obesity: Understanding Risk Factors
This study examines how muscle loss (sarcopenia) relates to obesity in adults seeking weight-loss treatment. Researchers will assess your muscle strength and physical function to identify risk factors, which could help improve future obesity care.
SingaporeAges 21–100 - NCT07540949Recruiting
Lemon Fermented Product for Weight and Metabolism in Adults
This study tests whether a lemon fermented product supplement can help improve metabolism and metabolic health in adults with obesity. Participants will take capsules and have their metabolism and health markers measured over time.
TaoyuanAges 18–65 - NCT07521631RecruitingPhase 2
HDM1005 versus Tirzepatide for weight management in obese adults
This study tests whether a new injectable medication called HDM1005 works as well as tirzepatide (a GLP-1 drug) for weight loss in adults with obesity but no diabetes. Both medications work similarly in the body to help control appetite and weight.
ShanghaiAges 18–65 - NCT07518407Recruiting
Nutrition Education and Diet Guidance While Using GLP-1 Medication
This study teaches adults on GLP-1 medication (like Ozempic or Wegovy) how to eat better and lose weight using a smartphone app. Researchers want to see if personalized nutrition advice helps you get better results from your medication.
Columbia, South CarolinaAges 18–65 - NCT06759623Recruiting
Lung function and anesthesia in bariatric surgery
This study checks how well your lungs work after you receive anesthesia (sleep medicine) for weight-loss surgery. It will help doctors choose the best anesthetic for people with obesity.
GdanskAges 18 years+ - NCT07508020RecruitingPhase 1
How a new medicine affects appetite and metabolism in people with obesity
This study tests an experimental drug (NNC0487-0111) to see how it changes food intake, appetite, and the way your body processes food after meals. It is for adults with obesity who do not have diabetes.
BerlinAges 18–64 - NCT07513168RecruitingPhase 4
Low-dose semaglutide for weight loss in obese adults
This study tests whether a low dose of semaglutide (a once-weekly injection) can help obese adults without diabetes lose weight. Semaglutide works by reducing appetite and helping your body use food differently.
Hyderābād, SindhAges 18 years+ - NCT07494253Enrolling by invitation
Mulberry leaf extract for blood sugar after meals in obese youth
This study tests if a mulberry leaf extract (Reducose) can help lower blood sugar spikes after meals in children and teenagers with obesity. The goal is to see if a natural supplement can improve glucose control.
BariAges 6–16 - NCT07495904Recruiting
Weight loss drug effects on body muscle with extra protein
This trial tests a weight-loss medication (GLP-1 receptor agonist) combined with dietary protein to see if it helps protect muscle while losing fat. It is for adults with obesity who are not taking certain other medications or supplements.
HeraklionAges 30–65 - NCT07496463Enrolling by invitationPhase 2
Setmelanotide for weight loss in pseudohypoparathyroidism type 1a
This study tests an experimental medication called setmelanotide to see if it can help with weight loss in people who have pseudohypoparathyroidism type 1a (PHP1a), a rare genetic condition that often leads to obesity. The goal is to find a new treatment option for weight problems related to PHP1a.
Boston, MassachusettsAges Any age - NCT07497555Recruiting
Pecan nut oil for inflammation in overweight adults
This study tests if taking pecan nut oil every day can reduce inflammation in adults who are overweight. It may help improve health and lower the risk of future disease.
Monterrey, Nuevo LeónAges 18–55 - NCT07482436Recruiting
Airway ultrasound vs laryngoscopy in obesity
This study compares two ways of checking the airway before surgery in people with obesity: a breathing tube placed with the help of ultrasound (a handheld device that uses sound waves) versus a standard laryngoscope (a lighted tool). The goal is to see which method is safer and easier for larger patients.
TrabzonAges 18 years+ - NCT07478653Recruiting
Dental health study for teens with severe obesity
This study looks at whether gum health is linked to heart health in teens with severe obesity. It may help find ways to reduce heart risks by improving dental care.
Lexington, KentuckyAges 12–17 - NCT07463846RecruitingPhase 1/Phase 2
Study of ALN-2232 in people with obesity
This trial tests an investigational drug called ALN-2232 in people with obesity to see if it can help with weight management. You may be able to join if you have a BMI between 30 and 40 and do not have diabetes or take other weight-loss or diabetes medications.
Mount RoyalAges 18–65 - NCT06790329Recruiting
Weight loss trial using stomach stapling and surface ablation
This trial tests a combined procedure that uses stomach stapling (endoscopic sleeve gastroplasty) plus ablation of the stomach lining to help with weight loss. It is for people with obesity who have not been able to lose weight with diet, exercise, or medication alone.
ShatinAges 18–70 - NCT07467694Recruiting
Postnatal exercise to activate baby's brown fat
This trial tests if exercise after childbirth can activate your baby's brown fat, which helps with metabolism. It may benefit mothers and their healthy, full-term babies.
Boston, MassachusettsAges 18–45 - NCT06367296Recruiting
Resistance Exercise for Older Women with Obesity
This study tests whether a supervised resistance exercise program (like lifting weights) can help older women with obesity improve their health. It is designed for women who are able to exercise safely and want to see if strength training can make a difference.
Temuco, AraucaniaAges 60–79 - NCT06303544Recruiting
Healthy eating and activity for Alaska Native preschoolers
This study tests a program to help Alaska Native preschoolers eat healthier and be more active. It aims to lower the risk of obesity by making small changes to daily routines at school and home.
Anchorage, AlaskaAges 3–5 - NCT06800911Recruiting
Metacognitive beliefs in obesity
This study explores how thinking patterns and beliefs about one's own thoughts may be linked to obesity. It aims to understand the role of metacognition in people with severe obesity.
Oggebbio, VerbaniaAges 18–65 - NCT07447440Recruiting
Study on natural fats linked to obesity-related diseases
This trial explores how certain natural fats in the body might affect diseases linked to obesity, such as breast cancer. It aims to see if these fats can reduce inflammation and improve health.
Pamplona, NavarreAges Any age
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Common questions
- Are there clinical trials for overweight or obese?
- Yes. Clin2 currently lists 1,472 recruiting overweight or obese studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.