Clinical trials
Overweight or Obese clinical trials
Below are recruiting overweight or obese clinical trials, each written for real people, not researchers. We’re tracking 1,535 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05351476Recruiting
Exercise program for metabolism in postmenopausal women
This trial studies whether a structured exercise program can improve how your body uses fat. It is designed for postmenopausal women with higher weight and prediabetes who are not currently exercising much.
Tallahassee, FloridaAges 50–75 - NCT05394363Recruiting
Victoria children birth-cohort study with parent/guardian consent
This study follows children born in a specific 2-year window and their parents or guardians over time. It helps researchers understand how children and families change as they grow, which can guide future health supports in Victoria.
Parkville, VictoriaAges 1 day+ - NCT05404061Recruiting
Study for people who don’t lose weight after bariatric surgery
This study looks at people who have had bariatric surgery but still struggle to lose weight (or lose it poorly). It aims to better understand how to help “poor responders” and what might be interfering with weight-loss results.
LondonAges 18–70 - NCT05414409RecruitingPhase 2
Gut microbiome study in young people with type 1 diabetes
This Phase 2 study looks at the gut microbiome (the bacteria in your intestines) in youth with type 1 diabetes, and how metformin may work differently through the gut. It may help researchers understand mechanisms and future treatment options.
Indianapolis, IndianaAges 11–18 - NCT05430178Recruiting
Study of liver fat changes in kids with fatty liver disease
This study looks at how metabolism works in children and teens who have (or do not have) nonalcoholic fatty liver disease (NAFLD), a condition where fat builds up in the liver. Participants may include healthy-weight controls, obese controls without NAFLD, and kids with NAFLD who are already scheduled for a liver biopsy for clinical reasons.
Oklahoma City, OklahomaAges 10–20 - NCT05432362Recruiting
Energy sensing brain study in depression and weight groups
This study tests how the brain and body respond to “energy sensing” in people with depression and in people with different body weights. You may be asked to do assessments and follow specific health and diet rules so the researchers can compare groups.
Graz, StyriaAges 18–40 - NCT05437809Recruiting
Study how people’s brains respond to ultra-processed foods
This study looks at how brain and body reward signals change after eating different ultra-processed foods. It may help researchers understand how food choices and metabolism relate to weight and mood in some people.
Philadelphia, PennsylvaniaAges 18–65 - NCT05443100Recruiting
Testing whole-body cold therapy for metabolic, neurologic, or fibromyalgia pain
This trial studies whether a whole-body cold therapy called “WBC” can help people with certain metabolic conditions, neurologic conditions, or fibromyalgia. You may be able to join if you meet age and weight requirements and don’t have certain medical or safety risks.
Oggebbio, Verbano-Cusio-OssolaAges 18–65 - NCT05464186Recruiting
Whole versus nonfat milk effects on kids’ body composition
This study compares whole milk vs nonfat milk to see how each affects body composition (such as fat and lean mass) in children. It may help families understand whether milk type makes a difference for healthy growth.
Boston, MassachusettsAges 9–12 - NCT05468437Recruiting
Online nutrition coaching for people with spinal cord injury
This study tests whether telenutrition (nutrition coaching by phone/tablet) can help people with spinal cord injury manage their weight and health. It may be a good fit if you’re mainly using a wheelchair, can use an iPad, and live in California.
San Jose, CaliforniaAges 20 years+ - NCT05476627Recruiting
Study risk factors for kidney disease from metabolic conditions
This study looks at risk factors and body “omics” information (like blood/tissue patterns) to better understand chronic kidney disease caused by metabolic diseases. It may help researchers find better ways to predict or manage kidney problems in people with these conditions.
Beijing, Beijing MunicipalityAges 18–80 - NCT05630482Recruiting
Healthy Family program for expecting military parents
This trial tests a “Healthy Family Foundations” program for two-parent military families expecting their first baby. It may help improve family support and parenting readiness during pregnancy and early infancy.
Nellis Air Force Base, NevadaAges 18–60 - NCT05498675Recruiting
Sacubitril/valsartan study for high blood pressure by body size
This study tests how sacubitril/valsartan may affect heart function in people with high blood pressure, and whether results differ by body size (BMI). You may benefit by getting closer heart monitoring, though it depends on whether you fit the safety and medical criteria.
Beijing, Beijing MunicipalityAges 18–70 - NCT05514288Recruiting
Endoscopic weight-loss procedures for people with excess weight
This study looks at how well an endoscopic (camera-based) weight-loss procedure helps people lose weight and whether it’s safe. It may be for people who are considering this approach, including some who previously had bariatric surgery but didn’t keep the weight off.
Los Angeles, CaliforniaAges 18–75 - NCT05542407RecruitingPhase 1
ONC201 plus atezolizumab for endometrial cancer and obesity
This Phase 1 study tests ONC201 together with atezolizumab in people with metastatic or returning endometrial cancer, especially when obesity may be driving the cancer. It aims to find a safe dose and see whether the combination can slow the cancer’s growth.
Chapel Hill, North CarolinaAges 18 years+ - NCT05545306Recruiting
Study tests how extra calories change your daily energy use
This study looks at how eating more calories affects your body’s natural heat production and total energy use over a full day. It may help researchers better understand how the body manages weight and energy.
Phoenix, ArizonaAges 18–60 - NCT05569785Recruiting
Bariatric surgery and exercise to study muscle changes
This study looks at how exercise and bariatric surgery (gastric bypass or sleeve) affect your muscle strength and health. You may be eligible if you are an adult with obesity who is planning one of these surgeries.
DerbyAges 18–70 - NCT05585190Recruiting
Sit-stand desk study for people at diabetes risk
This trial tests whether using a sit-stand desk at work helps people who are overweight and at risk for diabetes. Participants may be asked to change how much they sit during the workday to improve health markers.
Milwaukee, WisconsinAges 18–79 - NCT05589155Recruiting
Using a phone app to improve blood sugar and weight
This study looks at whether a mobile phone app can help people with type 2 diabetes improve their health habits, including blood sugar monitoring and weight. You may be able to join if you already check your blood sugar daily and are able to use a smartphone.
San Diego, CaliforniaAges 18–64 - NCT05602805Recruiting
Study using a health data bank for weight management
This study builds a data bank to help track how people manage overweight or obesity at the hospital. It may help improve care for future patients by learning what treatments and outcomes work best.
Québec, QuebecAges 18 years+ - NCT05623007Recruiting
Diet and gut bacteria study for vaccinated teens with COVID
This trial tests whether changing diet can shift gut bacteria in overweight or obese teens after COVID-19 vaccination. The goal is to see if dietary changes can affect health markers related to the gut and immune system.
Jakarta Pusat, DKI JakartaAges 12–17 - NCT05646901Recruiting
Study how gut bacteria may affect loss of eating control
This study looks at how gut bacteria and the brain may be involved when people struggle to control eating. It may help researchers understand the body’s signals behind eating control problems.
Girona, GironaAges 30–65 - NCT05651724Recruiting
MASH screening study for people with diabetes or obesity
This study screens participants for MASH (a type of liver fat inflammation) using information about your health and risk factors. It may help you and your care team learn whether you could have MASH and need follow-up.
Brussels, Vlaams-brabantAges 18–75 - NCT05653258RecruitingPhase 2/Phase 3
Study cells in fat tissue and aging cells in older adults
This study uses a special lab test on tiny samples from body fat to map different cell types and “senescent” (aging) cells. It may help researchers understand how aging and obesity are linked, which could guide future treatments.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for overweight or obese?
- Yes. Clin2 currently lists 1,535 recruiting overweight or obese studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.