Clinical trials · Chicago, IL
Overweight or Obesity clinical trials in Chicago
We’re tracking 54 recruiting overweight or obesity studies with a site in or near Chicago — including Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT07392190RecruitingPhase 3
Study of eloralintide for people with persistent obesity
This trial tests if adding eloralintide helps people who are still obese or overweight while taking weekly incretin therapy. It aims to support additional weight loss for those who haven't reached their goals.
Chicago, IllinoisAges 18 years+ - NCT06477120Recruiting
Time-restricted eating for pregnant women with severe obesity
This study tests whether eating only during a set window of time each day (time-restricted eating) can help manage weight gain during pregnancy for women with severe obesity. It might offer a safe, simple way to support a healthy pregnancy.
Chicago, IllinoisAges 18–44 - NCT06504914Recruiting
A lifestyle program for Black female breast cancer survivors
This study tests a lifestyle program designed for Black women who have survived breast cancer. It aims to help with high blood pressure or weight management by teaching healthy cooking and habits.
Chicago, IllinoisAges 18–99 - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Chicago, IllinoisAges 18 years+ - NCT07497880RecruitingPhase 2
Study of a new pill for weight loss in adults with obesity
This trial tests a daily pill called KAI-7535 to see if it helps people with obesity or overweight lose weight safely. It is for adults who have a body mass index (BMI) of 27 or higher and at least one weight-related health problem, such as high blood pressure or type 2 diabetes.
Chicago, IllinoisAges 18–75 - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
Chicago, IllinoisAges 18–75 - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Chicago, IllinoisAges 12–17 - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Chicago, IllinoisAges 6–17 - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Chicago, IllinoisAges 18 years+ - NCT07639021RecruitingPhase 2
Testing Different Dose Schedules of a New Weight Loss Medicine
This study tests a new injectable medication (NNC0662-0419) designed to help people with obesity lose weight. Researchers are comparing different ways of increasing the dose to find the safest and most effective approach.
Chicago, IllinoisAges 18 years+ - NCT07684235RecruitingPhase 3
Long-term study of a weight-loss drug for trial graduates
This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.
Chicago, IllinoisAges 18–99 - NCT07571109RecruitingPhase 3
Weight Loss Medicine for Sleep Apnea on CPAP
This study tests a new injectable medicine (NNC0487-0111) to help people lose weight and improve obstructive sleep apnea (a breathing condition during sleep). You must already be using a CPAP machine (positive airway pressure device) for your sleep apnea.
Chicago, IllinoisAges 18 years+ - NCT06937099RecruitingPhase 3
Testing two drugs for Crohn's with weight issues
This trial tests two study drugs, mirikizumab and tirzepatide, in people with moderate to severe Crohn's disease who also have overweight or obesity. The goal is to see if these treatments can help control Crohn's symptoms and inflammation.
Chicago, IllinoisAges 18–70 - NCT06239116RecruitingPhase 1/Phase 2
RM-718 for obesity from hypothalamus injury or Prader-Willi syndrome
This study tests a new medicine called RM-718 for people with severe obesity linked to a specific brain pathway (MC4R). It may help if your obesity is due to a brain injury or tumor affecting the hypothalamus, or if you have Prader-Willi syndrome.
Chicago, IllinoisAges 12–65 - NCT06439277RecruitingPhase 3
Tirzepatide for teens with obesity and related health problems
This study tests a medication called tirzepatide (a once-weekly injection) to help teenagers with obesity and related health conditions lose weight. It aims to see if the drug is safe and effective for this age group.
Chicago, IllinoisAges 12–17 - NCT07332741RecruitingPhase 2
Food as medicine for better blood pressure
This study tests a program that provides healthy food and support to help people with high blood pressure and a BMI of 30 or higher eat better and control their blood pressure. If you join, you'll get guidance on the DASH diet (a heart-healthy eating plan) and text messages to help you stay on track.
Chicago, IllinoisAges Any age - NCT06760546RecruitingPhase 3
Testing setmelanotide for weight gain after brain injury
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Chicago, IllinoisAges 4 years+ - NCT06390345Recruiting
Telehealth lifestyle and exercise for COPD and sleep apnea
This study tests a telehealth program that combines lifestyle coaching and exercise to help people with both COPD and sleep apnea improve their breathing and daily function. It may be a good fit if you are overweight, have a history of smoking, and feel short of breath during light activity.
Chicago, IllinoisAges 18 years+ - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Melrose Park, IllinoisAges 18 years+ - NCT07575399RecruitingPhase 3
Switching to a New Weight-Loss Medication From Current GLP-1
This trial tests whether switching from your current GLP-1 medication (like Ozempic or Wegovy) to a new drug called maridebart cafraglutide works as well or better for weight management. You must have already lost at least 10% of your body weight on your current GLP-1 and be doing well with it.
Skokie, IllinoisAges 18–99 - NCT07282600RecruitingPhase 3
Study of eloralintide for type 2 diabetes and weight
This study tests a new medicine called eloralintide for people with type 2 diabetes who are overweight or have obesity. It aims to see if the drug can help with weight loss and blood sugar control.
Skokie, IllinoisAges 18 years+ - NCT07339423RecruitingPhase 3
A study of a new medicine for weight loss
This study tests a new medicine to see how well it helps people with excess body weight lose weight. It may be an option if you have tried to lose weight through dieting before but haven't had lasting success.
Skokie, IllinoisAges 18 years+ - NCT07509307RecruitingPhase 3
Study of a new medicine for weight loss and knee pain in osteoarthritis
This trial tests if a new medicine, NNC0487-0111, can help people with excess weight and knee osteoarthritis lose weight and reduce knee pain. It is for people who have had knee pain for at least three months and who can stop taking pain relievers for short periods before study visits.
Skokie, IllinoisAges 18 years+ - NCT07503210RecruitingPhase 3
Study of a new medicine to maintain weight loss
This study tests an investigational medicine to help people who have lost weight keep it off. It's for adults without diabetes who haven't used similar weight-loss drugs before.
Skokie, IllinoisAges 18 years+
Hear when a new Overweight or Obesity trial opens near Chicago, IL
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Overweight or Obesity trials in other cities
Where these studies are running near Chicago
Institutions with a site for the recruiting overweight or obesity studies listed above.
- Ann & Robert H. Lurie Children's Hospital of Chicago · 5 studies
- Endeavor Health · 4 studies
- Great Lakes Clinical Trials · 4 studies
- Evanston Premier Healthcare Research · 3 studies
- University of Illinois · 3 studies
- Cedar Crosse Research Center · 2 studies
- Clinical Investigation Specialists, Inc · 2 studies
- ASHA Clinical Research
What taking part in a overweight or obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting overweight or obesity studies in Illinois.
Common questions
- Are there overweight or obesity clinical trials near Chicago?
- Yes. We're currently tracking 54 recruiting overweight or obesity studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a overweight or obesity study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New overweight or obesity studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.