Clinical trials · Ohio
Overweight or Obesity clinical trials in Ohio
We’re tracking 54 recruiting overweight or obesity studies with a site in Ohio — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT07268417Enrolling by invitation
Group lifestyle program for obesity in primary care
This study tests if group medical visits with lifestyle coaching can help people with obesity lose weight and improve their health. It takes place at Cleveland Clinic primary care offices.
Cleveland, OhioAges 20–75 - NCT07702461Recruiting
Resistance training survey for people on weight loss meds
This trial is an online survey to understand how people taking GLP-1 medications (like Ozempic or Wegovy) are doing with resistance training. If you're an adult on a stable dose of a GLP-1 med for weight or diabetes, your input can help shape better exercise advice.
Columbus, OhioAges 18 years+ - NCT07684235RecruitingPhase 3
Long-term study of a weight-loss drug for trial graduates
This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.
Cincinnati, OhioAges 18–99 - NCT07684144RecruitingPhase 3
Long-term study of a weight-loss medication for people who completed an earlier trial
This study tests the long-term effects of a medication called maridebart cafraglutide for weight management. It is for people who already completed a 72-week study of this drug and want to continue treatment.
Cincinnati, OhioAges 18–99 - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Columbus, OhioAges 18 years+ - NCT07571109RecruitingPhase 3
Weight Loss Medicine for Sleep Apnea on CPAP
This study tests a new injectable medicine (NNC0487-0111) to help people lose weight and improve obstructive sleep apnea (a breathing condition during sleep). You must already be using a CPAP machine (positive airway pressure device) for your sleep apnea.
Cincinnati, OhioAges 18 years+ - NCT07571005RecruitingPhase 3
Testing a New Weight-Loss Medicine for Sleep Apnea
This study tests whether a new injectable medicine called NNC0487-0111 helps people with excess weight and moderate-to-severe obstructive sleep apnea (a condition where breathing stops repeatedly during sleep) lose weight and improve their sleep apnea—without needing a CPAP machine. The goal is to see if better weight loss can reduce sleep apnea symptoms.
Cincinnati, OhioAges 18 years+ - NCT07409064Recruiting
Exercise's effect on cholesterol and blood vessels in teens
This study looks at how a structured exercise program affects cholesterol and blood vessel health in teens with obesity. It may help understand if exercise can improve heart health.
Cincinnati, OhioAges 10–20 - NCT07253285RecruitingPhase 3
Study on cagrilintide and CagriSema for kids with excess weight
This trial tests two new medicines (cagrilintide and CagriSema) to see if they help children and teens lose weight. It's for young people who have tried lifestyle changes without enough success.
Columbus, OhioAges 8–18 - NCT07244445Recruiting
Pistachios with GLP-1 therapy for weight and nutrition
This study tests whether adding pistachios to your diet can improve nutrition and weight loss while you are already on a GLP-1 medication like Wegovy, Ozempic, or Mounjaro. It is open to adults who have been on the medication for at least three months.
Clevland, OhioAges 18–80 - NCT07244458Recruiting
Peanuts and GLP-1 Medications Study
This study looks at how adding peanuts to your diet affects nutrition and health in people who are already taking weight-loss medications like Ozempic, Mounjaro, or Wegovy. It aims to see if peanuts can improve your diet quality and help with weight management.
Clevland, OhioAges 18–80 - NCT06028113RecruitingPhase 2
A weight gain prevention program for high-risk babies in primary care
This study tests a program to help prevent unhealthy weight gain in babies at higher risk for obesity. Families will get extra support during regular check-ups at a pediatric clinic.
Cincinnati, OhioAges 1 day+ - NCT07219589RecruitingPhase 1
Study of HM17321 in healthy and obese participants
This trial tests a new medicine, HM17321, to see how the body processes it. It is for healthy adults and adults with obesity who want to help find new treatment options.
Cincinnati, OhioAges 18–65 - NCT07817875RecruitingPhase 3
Tirzepatide for weight loss in children aged 6 to under 12
This study tests a once-weekly medication called tirzepatide to help children aged 6 to under 12 with obesity lose weight. It compares the medication to a placebo (inactive shot) to see if it safely helps with weight loss in this age group.
Cincinnati, OhioAges 6–11 - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Maumee, OhioAges 18 years+ - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Canton, OhioAges 18 years+ - NCT07058155RecruitingPhase 4
TIPS and weight-loss surgery for liver disease with high blood pressure
This trial tests if doing a TIPS procedure (to lower blood pressure in the liver) before weight-loss surgery (sleeve gastrectomy) helps people with advanced liver disease. It's for those who have cirrhosis and very high blood pressure in the liver, and who qualify for sleeve gastrectomy.
Cleveland, OhioAges 18–70 - NCT06899178RecruitingPhase 2
Atomoxetine for genetic obesity due to MC4R changes
This trial tests a medicine called atomoxetine (Strattera) to help people with a specific genetic form of obesity lose weight. It may be an option if you have a change in the MC4R gene and have not used certain other medications recently.
Columbus, OhioAges 6 years+ - NCT06802081RecruitingPhase 2
Tirzepatide for weight loss in people with atrial fibrillation
This study tests whether tirzepatide, a medication that helps with weight loss and blood sugar control, can improve the heart rhythm condition atrial fibrillation. If you have AFib and are overweight or obese, this trial may be an option for you.
Cleveland, OhioAges 18–80 - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Cincinnati, OhioAges 18 years+ - NCT07587437Enrolling by invitation
Magnetic Camera Exam Before Weight-Loss Surgery
This study tests a swallowable magnetic camera to examine your stomach and small intestine before bariatric (weight-loss) surgery. The camera may help doctors plan your surgery and catch any issues beforehand.
Cleveland, OhioAges 18 years+ - NCT07151105Recruiting
Vitamin C for gut health in adults with obesity
This trial tests whether taking vitamin C supplements helps improve gut barrier function in adults with obesity. You'll follow a low-fruit-and-vegetable diet for two, two-week periods.
Columbus, OhioAges 18–50 - NCT06746623Recruiting
Non-endoscopic screening for Barrett's in veterans without reflux
This trial tests a new, non-endoscopic screening method for Barrett's esophagus (a condition that can lead to cancer) in veterans who do not have chronic acid reflux. It aims to find early signs of the condition using a simple swallowable device, potentially avoiding the need for a traditional endoscopy.
Cleveland, OhioAges 40–85 - NCT06581120Enrolling by invitation
Stomach ultrasound study for diabetes and obesity
This study uses ultrasound to see how GLP-1 RA medications (like Ozempic) affect the stomach in people with type 2 diabetes and obesity. It may help doctors better understand how these medicines work.
Cincinnati, OhioAges 10–25
Overweight or Obesity trials by city in Ohio
Where these studies are running in Ohio
Institutions with a site for the recruiting overweight or obesity studies listed above.
- Cleveland Clinic · 3 studies
- Velocity Clinical Research · 3 studies
- Advanced Medical Research · 2 studies
- Cincinnati Children's Hospital Medical Center · 2 studies
- CTI Clinical Research Center · 2 studies
- Nationwide Children's Hospital · 2 studies
- The Ohio State University · 2 studies
- University Hospitals Cleveland Medical Center · 2 studies
What taking part in a overweight or obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Overweight or Obesity trials in other states
Common questions
- Are there overweight or obesity clinical trials in Ohio?
- Yes. We're currently tracking 54 recruiting overweight or obesity studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a overweight or obesity study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New overweight or obesity studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.