Clinical trials
Pacemaker clinical trials
Below are recruiting pacemaker clinical trials, each written for real people, not researchers. We’re tracking 76 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07430553Recruiting
Comparing pacemakers for better heart function in heart failure
This trial compares three types of advanced pacemakers (cardiac resynchronization therapy devices) to see which works best for improving heart function and reducing abnormal heart rhythms in people with heart failure.
London, Greater LondonAges 18 years+ - NCT06814574Recruiting
Pacemaker after tricuspid valve replacement
This study looks at whether people who need a new tricuspid heart valve also need a pacemaker soon after. Researchers want to learn more about heart rhythm changes after valve replacement.
München, BavariaAges Any age - NCT07424690Recruiting
Comparing ablation with medication care for older adults with atrial fibrillation
This study compares two approaches for older adults with atrial fibrillation: a procedure called catheter ablation (which uses heat or cold to fix the heart's rhythm) versus conservative care (medications and lifestyle changes). The goal is to see which approach is better for improving quality of life and reducing symptoms in people aged 78 and above.
LinköpingAges 78 years+ - NCT06707662Recruiting
Pacing methods to protect heart function
This trial tests two pacing approaches to see which one better prevents weakening of the heart's main pumping chamber. It's for people who need a pacemaker for a slow heart rhythm and are expected to rely on it heavily.
BarcelonaAges 18 years+ - NCT07393009Recruiting
Study of a new left bundle branch area pacing system
This study tests a new type of pacemaker system that delivers pacing to the left side of the heart through a lead placed deep in the wall between the lower chambers. The goal is to see if this approach works well for people who need a pacemaker or CRT.
AdelaideAges 18 years+ - NCT06842940Recruiting
Predicting best lead placement during pacemaker or ICD surgery
This study tests whether a measurement called 'slew rate' can help doctors find the best spot to attach the leads (wires) from a pacemaker or ICD to your heart. It may lead to more stable and effective placement during your procedure.
FidenzaAges 18–100 - NCT07356505Recruiting
Micra AV2 pacemaker study for heart block
This study tests a small pacemaker, the Micra AV2, for people with a type of heart block that affects electrical signals between the upper and lower heart chambers. The goal is to see how well and safely the device works.
Leuven, Flemish BrabantAges 18 years+ - NCT07342036Recruiting
Study of new heart device leads and tricuspid valve leakage
This study looks at how a new pacemaker or defibrillator lead may affect the tricuspid valve (the valve between the right upper and lower heart chambers). It helps doctors understand if the lead causes leakage (regurgitation) over time.
Bad Oeynhausen, North Rhine-WestphaliaAges 18 years+ - NCT07250529Recruiting
Comparing two pacemaker pacing methods for heart block
This study compares two types of pacemaker pacing methods in people with heart block and normal heart pumping function. It looks at how often short bursts of fast heart rhythm occur in the upper heart chambers, which may help improve long-term heart health.
PátraiAges 18 years+ - NCT07209852Recruiting
Pacing the heart's left bundle branch area with a new lead
This trial tests a new pacing lead placed in the left bundle branch area of the heart. It is for people who need a pacemaker for certain slow or irregular heart rhythms.
BrugesAges 18 years+ - NCT07201363Recruiting
Inflammation and scarring markers after TAVI
This study looks at markers of inflammation and scarring in people who develop heart rhythm problems after having a TAVI procedure (a minimally invasive valve replacement). It may help doctors understand and predict these complications.
Rijeka, CroatiaAges 18 years+ - NCT06937658Recruiting
Better remote care for heart device patients
This study tests a new alert system for people with pacemakers or defibrillators that can send information directly to your care team. The goal is to improve how quickly problems are found and treated.
Boston, MassachusettsAges 18 years+ - NCT06699342Recruiting
Pacing and heart ablation for atrial fibrillation
This trial tests a combination of heart pacing and a specialized ablation procedure in older adults with permanent atrial fibrillation that hasn't improved with other treatments. It aims to improve symptoms and reduce hospital stays related to heart failure.
Seoul, Jongno-guAges 65 years+ - NCT06561932Recruiting
Leadless pacemaker for heart failure resynchronization
This trial tests a completely leadless pacemaker (WiSE® CRT) for heart failure patients who need cardiac resynchronization therapy (CRT). It aims to avoid the long-term risks of traditional wires (leads) in the heart.
Birtinya, QueenslandAges 22 years+ - NCT05029570Recruiting
Heart rate control for permanent atrial fibrillation and heart failure
This trial studies whether a strategy to regularize (control) heart rate can improve outcomes in people who have permanent atrial fibrillation and heart failure. It focuses on people with recent heart-failure hospitalization and checks several heart, kidney, and health-condition limits to keep the study safe.
Madrid, MadridAges 18 years+ - NCT06299514Recruiting
Pacemaker and ablation for heart failure with atrial fibrillation
This trial tests if a pacemaker plus an ablation procedure can improve heart failure symptoms in people with atrial fibrillation. It is for those with moderate to severe heart failure who are already on the right medications.
Victoria, British ColumbiaAges 18 years+ - NCT06262295Recruiting
Monitoring the safety of AVEIR leadless pacemakers
This study tracks the safety and performance of AVEIR VR LP and AVEIR AR LP leadless pacemakers in people who already have them or will get one. It helps doctors and researchers see how well these small heart devices work over time.
La TroncheAges 18 years+ - NCT03475498Recruiting
ECG and heart ultrasound before and after pacemaker implantation
This study looks at how heart test results—electrical tracing (ECG) and heart ultrasound (echocardiogram)—change after a device is implanted. It may help doctors better predict who develops PICM (a certain pacing-related heart weakening) and how that affects outcomes.
ChungjuAges 20 years+ - NCT06152406Recruiting
Ablate and Pace HIS for atrial fibrillation and heart failure
This study tests a new approach called 'Ablate and Pace HIS' for people with atrial fibrillation and heart failure who haven't improved with other treatments. It combines a heart ablation procedure with a special type of pacing to help your heart pump more efficiently and reduce symptoms.
Leicester, LeicestershireAges 18–100 - NCT06059638Recruiting
Pacemaker pacing for blood pressure control
This study tests whether adjusting the timing of a pacemaker can help lower blood pressure in people who already have or need a pacemaker. It could be an option for those whose blood pressure is not well controlled with medication.
Scottsdale, ArizonaAges 18 years+ - NCT05884359Recruiting
Mapping how a pacemaker is placed in the heart
This trial focuses on testing a new way to map (map out) where a specific pacemaker lead is placed in the heart for people getting left bundle branch area pacing. It may help doctors improve how the pacemaker is implanted and confirm the lead is in the right spot.
Boston, MassachusettsAges 18–88 - NCT03008291Recruiting
Heart pacemaker study for slow heartbeats and heart failure
This trial tests how pacing from a specific part of the heart (a “bundle” pacing approach) can affect people with heart failure and/or slow heart rhythms. It may help certain patients whose heart rhythm is too slow or who need a pacemaker and related devices.
Rochester, MinnesotaAges 18 years+ - NCT05127720Recruiting
Pacemaker monitoring to study sleep apnea long term
This study uses a pacemaker to track information over time related to sleep apnea. It also includes CT scans to help the researchers better understand what’s happening in and around the heart during sleep.
Innsbruck, TyrolAges 18 years+ - NCT05015660Recruiting
Testing left bundle pacing versus usual right pacing
This study compares a newer heart pacing method (left bundle branch pacing) to the standard method (right ventricular pacing) in people who need most of their heartbeats paced. It may help improve how well the heart pumps over time.
Montreal, QuebecAges 18 years+
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Common questions
- Are there clinical trials for pacemaker?
- Yes. Clin2 currently lists 76 recruiting pacemaker studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pacemaker trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pacemaker trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.