Clinical trials
Pain, Chronic Disease clinical trials
Below are recruiting pain, chronic disease clinical trials, each written for real people, not researchers. We’re tracking 456 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07286630Enrolling by invitation
Disability and fear avoidance in physical therapists
This study looks at how common disability and fear-related beliefs are among Egyptian physical therapists who have long-term low back pain. If you qualify, you will answer questionnaires about your pain, your thoughts about movement, and how it affects your daily life.
CairoAges 25–55 - NCT06989749Recruiting
Brain stimulation for affect and pain study
This study tests if a gentle electrical current applied to the scalp can change how people feel pain and manage emotions. It may help researchers find new ways to help people with pain.
Hanover, New HampshireAges 18–55 - NCT06277362Recruiting
New Leg-Saving Treatment for Critical Limb Ischemia
This study tests a new way to restore blood flow to the leg in people who have wounds or dead tissue on their foot and have run out of other treatment options. It's for those who have already tried angioplasty twice without success or have severely hardened small arteries.
Ancona, AnconaAges 18 years+ - NCT04209504Recruiting
Nerve block study for one-sided breathing muscle weakness after shoulder surgery
This trial tests whether a longer-lasting nerve block during shoulder surgery can better manage pain and affect one-sided diaphragm (breathing muscle) weakness. It may help people having planned (first-time) shoulder surgery who are able to follow study pain-checks.
Durham, North CarolinaAges 18–80 - NCT05417685Enrolling by invitation
Digital physical therapy for musculoskeletal pain
This trial studies a smartphone/tablet-based care program to help people with neck, back, shoulder, elbow, wrist/hand, hip, knee, or ankle pain. It may help reduce pain and improve function using guided exercises, as long as it is safe for you to do light-to-moderate activity.
Draper, UtahAges 18 years+ - NCT05712395Recruiting
Pain-free exercise program for people with leg artery disease
This trial tests a new kind of exercise that is meant to be non-ischemic (not reduce blood flow) and pain-free, to see if it helps people with peripheral artery disease (PAD) who get leg pain when walking. You may be eligible if you have PAD confirmed by specific treadmill and blood-pressure measurements and meet the exercise and health safety requirements.
Oklahoma City, OklahomaAges 40 years+ - NCT07337902Recruiting
Comparing pain medicines for menstrual cramps in Crohn’s disease
This study tests two common over-the-counter pain relievers (ibuprofen and acetaminophen) to see which works better for menstrual cramps in women who also have Crohn's disease while in remission. If you have Crohn's and painful periods, this may help you find a safer option.
Chapel Hill, North CarolinaAges 18–44 - NCT07307846Recruiting
Steroid injection for neck pain and arm feeling
This study tests whether a steroid injection in the neck can improve your sense of arm position (proprioception) along with pain. It may help if you have chronic neck pain that travels down one arm due to a herniated disc.
Pendik, IstanbulAges 18–65 - NCT06708000Enrolling by invitationPhase 3
Personalized testing for new chest pain
This trial compares a personalized evaluation approach to standard care for people with new chest pain who might have heart disease. It aims to see if tailoring tests can improve diagnosis and outcomes.
HerningAges 30–75 - NCT07844772Recruiting
Psoriasis treatment and nerve pain study
This study looks at how different psoriasis treatments affect nerve-related pain and sensitivity. It compares patients on biologic injections, standard pills, or creams to see if treatment type matters for pain and skin symptoms.
Istanbul, IstanbulAges 18 years+ - NCT07413107Recruiting
Italian version of a back pain disability questionnaire
This study is testing a new Italian questionnaire that measures how much low back pain affects your daily life. It's for people who have had low back pain for at least 3 months and speak Italian.
Lissone, MilanoAges 18–90 - NCT07090668Recruiting
Ear stimulation for pain in sickle cell disease
This trial tests a safe, non-drug device that gently stimulates the ear to help reduce pain in children with sickle cell disease who are in the hospital for a pain crisis. It may offer a new way to manage pain without extra medication.
Atlanta, GeorgiaAges 7–18 - NCT05985148RecruitingPhase 1
Radiosurgery for chronic chest or stomach wall pain
This trial tests whether a precise, one-time radiation treatment (stereotactic radiosurgery) can relieve long-term pain in the chest or stomach wall. It may be an option for people whose pain is not well controlled with standard pain medicines.
Basking Ridge, New JerseyAges 18 years+ - NCT07242573Recruiting
Exercise and brain stimulation for fibromyalgia
This study tests if combining physical exercise with a gentle brain stimulation technique can improve pain, sleep, and fatigue in people with fibromyalgia.
Warsaw, Masovian VoivodeshipAges 20–80 - NCT06903442Recruiting
Helping ER chest pain patients understand heart risk
This study is testing a new way to talk with people about their heart health after they come to the Emergency Room with chest pain. It aims to help you understand your risk and what you can do to prevent future problems.
EdinburghAges 18 years+ - NCT07794527Recruiting
Nerve blocks to improve recovery after heart bypass surgery
This study tests whether giving multiple nerve blocks (numbing injections near nerves) during off-pump heart bypass surgery can improve your recovery and pain control. It aims to see if these blocks help you feel better and recover faster after surgery.
CairoAges 18–65 - NCT06776965Recruiting
Ultra-processed foods and rheumatic disease study
This study explores how eating ultra-processed foods affects people with chronic rheumatic diseases like rheumatoid arthritis, spondyloarthritis, or osteoarthritis. It aims to understand if diet plays a role in symptom management.
LyonAges 18 years+ - NCT07830836Enrolling by invitation
Physiotherapy and osteopathy for recent neck, back, or jaw pain
This study tests whether physiotherapy and osteopathic treatment can help relieve recent (acute) pain in the neck, lower back, or jaw joint. It aims to understand if these hands-on therapies reduce pain and improve jaw function.
Gorzów Wielkopolski, Lubusz VoivodeshipAges 20–40 - NCT06843018RecruitingPhase 2
Spray vs lozenge for sore throat from infection
This trial tests a new spray with anesthetic for sore throat caused by infections like pharyngitis. It compares the spray to a lozenge (Septolete Total) to see which works better and is safer.
Engel'sAges 18–75 - NCT07408414Recruiting
Pain relief after laser pilonidal sinus treatment
This trial studies which local numbing method works best to reduce pain after laser treatment for pilonidal sinus. It may help people with this condition feel more comfortable after their procedure.
PožegaAges 18 years+ - NCT07021638Recruiting
Walking training at home in virtual reality for children with chronic illnesses
This trial tests a home-based walking program using virtual reality games to help children with chronic conditions like cerebral palsy, obesity, or neuromuscular disease improve their walking and physical activity. It's designed to see if training at home with VR is effective and enjoyable.
AngersAges 6–17 - NCT07429669Recruiting
Comparing shoulder nerve blocks for pain and breathing
This study compares two different shoulder nerve blocks to see which one provides better pain relief after shoulder surgery while also checking how they affect your breathing. If you are having a shoulder arthroscopy, you may be eligible to help find the safest and most effective pain control option.
Yenimahalle, AnkaraAges 18–65 - NCT07826741Recruiting
Pain relief options for open inguinal hernia surgery
This study compares two ways to manage pain after open inguinal hernia repair: a spinal injection of morphine and a numbing injection near the abdomen. The goal is to find which method provides better pain relief with fewer side effects.
Yenimahalle, AnkaraAges 18–80 - NCT07747623Recruiting
Pain relief options for breast surgery
This study compares two ways of giving pain relief during breast surgery. It aims to find which method controls pain better after the operation.
Yenimahalle, AnkaraAges 18–80
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Common questions
- Are there clinical trials for pain, chronic disease?
- Yes. Clin2 currently lists 456 recruiting pain, chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain, chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain, chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.