Clinical trials
Pain Syndrome clinical trials
Below are recruiting pain syndrome clinical trials, each written for real people, not researchers. We’re tracking 288 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06969456Recruiting
Exercise and nerve stimulation for chronic back pain
This study looks at whether combining exercise with a type of nerve stimulation (called neuromodulation) can help people with long-term spinal pain that has nerve involvement. It may be an option if you have had pain for at least 6 months and it is severe.
Valencia, ValenciaAges 18–70 - NCT06807164RecruitingPhase 2
Comparing three injections for nerve pain after breast cancer surgery
This trial tests three different injections (a nerve block, capsaicin, or botox) to find which works best for chronic nerve pain after breast cancer surgery. If you have ongoing pain in a small area on your chest, armpit, or arm that started 3 to 9 months after surgery, this study may help you find better relief.
Lille, Hauts-de-FranceAges 18 years+ - NCT06102733Recruiting
Pelvic pain study for women and men
This trial is testing treatments for chronic pelvic pain, sacroiliac pain, groin pain, tailbone pain, and piriformis pain. It may help people with persistent pain in these areas find relief.
Surrey, British ColumbiaAges 20–99 - NCT07463729Recruiting
Back pain study using biofeedback training
This trial tests a stabilization training program using biofeedback (a device that shows you how your muscles are working) to treat chronic low back pain. It may help you strengthen the muscles supporting your spine and reduce your pain.
Tarnów, MałopolskaAges 30–65 - NCT05689944Recruiting
Dance therapy for teens with chronic pain
This trial studies whether dance therapy can help reduce chronic pain in teens when usual pain treatments haven’t worked well. It may be helpful if you’re followed in a pain clinic and are able to participate in movement-based sessions.
BronAges 12–20 - NCT06775535Recruiting
Spinal cord stimulation trial for chronic pain
This trial tests a closed-loop spinal cord stimulator that adjusts stimulation based on nerve signals. It may help people with chronic pain who are already scheduled to try this type of device.
RoeselareAges 18 years+ - NCT06807177Enrolling by invitation
Collagen injections for chronic neck pain
This trial tests if collagen injections into the neck can reduce chronic muscle pain and whether certain blood markers can show how well the treatment works. It may help if you have had neck pain for more than 12 weeks.
WarsawAges 18–65 - NCT07114913Recruiting
Carpal tunnel symptom location and pain study
This study looks at where carpal tunnel syndrome symptoms show up and how your body processes pain. By understanding this, doctors hope to find better ways to treat it.
Istanbul, UsküdarAges 18–65 - NCT06884852Recruiting
Preventing pain after mastectomy: nerve block vs. epidural
This study compares two methods to prevent long-term pain after breast cancer surgery: a nerve block using ultrasound guidance or an epidural. The goal is to see which helps women feel less pain months after their mastectomy.
CairoAges 18–65 - NCT07464639Enrolling by invitation
Comparing two ways to help shoulder pain with movement feedback
This study compares using ultrasound images (dynamic visual feedback) versus manual guidance to help activate shoulder blade muscles and improve space in the shoulder joint for people with shoulder pain when lifting their arm.
Long Beach, CaliforniaAges 18–70 - NCT06566664Enrolling by invitation
Nerve stimulation to help with arm surgery nerve blocks
This study tests if using a small electrical stimulator on the skin can make a nerve block work better for arm surgery. If you are having planned arm surgery and getting a nerve block, you may be able to join.
Stanford, CaliforniaAges 18 years+ - NCT06557993Recruiting
Nerve block injection for myofascial pain syndrome
This study tests a type of nerve block injection (called serratus posterior superior intercostal plane block) guided by ultrasound to see if it helps relieve pain from myofascial pain syndrome. It may be a treatment option for people with MPS who haven't had recent procedures.
IstanbulAges 18–65 - NCT06827262Recruiting
A procedure for vertebrogenic back pain relief
This trial tests a minimally invasive procedure that uses a special device to target and treat nerve-related back pain coming from the vertebrae (the bones in your spine). It may offer lasting relief without more major surgery.
Flagstaff, ArizonaAges 18 years+ - NCT06903962Recruiting
Mind-body program for chronic arm or hand pain
This trial tests whether a mind-body program can help people with long-term pain in their upper arm, forearm, or hand that is not caused by a clear physical injury. It focuses on retraining how your brain responds to pain triggers.
Boston, MassachusettsAges 18–60 - NCT07546084Recruiting
Exercise Program for Rotator Cuff Shoulder Pain
This study tests whether a special exercise program that trains you to focus your attention in different ways can reduce shoulder pain and improve function. You'll do exercises designed to help your rotator cuff (the muscles that stabilize your shoulder) while learning to shift your mental focus during movement.
IstanbulAges 18–65 - NCT07637084Recruiting
Light therapy for chronic pain and fatigue in Ehlers-Danlos Syndrome
This trial tests whether a non-invasive light therapy called photobiomodulation can reduce chronic pain and fatigue in people with hypermobile Ehlers-Danlos Syndrome (hEDS), a genetic condition affecting connective tissue. The light is applied to the skin and may help cells produce energy and reduce inflammation.
Boulogne-Billancourt, Île-de-France RegionAges 18 years+ - NCT06673108RecruitingPhase 2
Light therapy for chronic pelvic pain
This trial tests a light therapy device placed inside the vagina to treat long-term pelvic pain. It may help people whose pain hasn't been helped by other treatments.
Birmingham, AlabamaAges 18 years+ - NCT04144972Recruiting
Closed-loop deep brain stimulation for long-lasting nerve pain
This trial tests a “smart” deep brain stimulation device that senses your brain signals and adjusts treatment to reduce severe, long-lasting pain. It may help people whose pain has not improved with multiple pain medicines and surgery cannot fix the cause.
San Francisco, CaliforniaAges 22–80 - NCT07321483Recruiting
Reflex therapy for jaw pain
This trial tests if a special reflex therapy can help people with jaw muscle pain that isn't caused by joint damage. It might be a new way to reduce discomfort and improve function.
OlomoucAges 18 years+ - NCT05604066Enrolling by invitation
MRI scan to study muscle pain stiffness in low back or leg
This study uses a special MRI scan (magnetic resonance elastography) to measure how stiff muscles are in people with long-lasting low back or leg muscle pain. It may help researchers better understand myofascial pain—pain caused by tight, tender spots in muscle.
Rochester, MinnesotaAges 18 years+ - NCT07490366Recruiting
Exercise vs needle treatment for shoulder muscle pain
This study compares three treatments for long-term shoulder muscle pain: exercises, dry needling (tiny needles into tight muscle spots), and a numbing shot between muscle layers. It aims to find which works best for myofascial pain syndrome.
Istanbul, IstanbulAges 18–55 - NCT06338488Recruiting
Dry needling for shoulder pain from muscle knots
This trial tests if dry needling (inserting thin needles into muscle knots) can reduce shoulder pain caused by a condition called myofascial pain syndrome. It may help if you have a specific muscle knot in your shoulder blade area and significant pain.
Kütahya, TürkiyeAges 18–80 - NCT07639060Recruiting
Pain Relief Study Using Freezing Nerve Treatment
This study watches how well a freezing procedure works for chronic pain over 6 to 12 months. Your doctor thinks this procedure could help your pain, and the study simply tracks your recovery through questionnaires to help doctors understand if it works.
Old Saybrook, ConnecticutAges 18 years+ - NCT07543484Recruiting
Tennis Serve Movement Study for Shoulder Pain
This research study examines how your shoulder muscles and joints move during a tennis serve, comparing players with shoulder pain to those without. The goal is to better understand shoulder injuries in tennis and help prevent or treat them.
TaipeiAges 18–40
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Common questions
- Are there clinical trials for pain syndrome?
- Yes. Clin2 currently lists 288 recruiting pain syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.