Clinical trials
Pain Syndrome clinical trials
Below are recruiting pain syndrome clinical trials, each written for real people, not researchers. We’re tracking 267 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03168802Recruiting
Ultrasound and nerve treatment for facet-joint low back pain
This study tests whether a procedure that uses focused ultrasound (MRgFUS) and/or a radiofrequency nerve treatment can reduce long-lasting low back pain caused by facet-joint arthritis. It may help people whose pain improves strongly after a targeted numbing injection to specific back nerves.
Taipei, Please SelectAges 20–79 - NCT07525063Enrolling by invitation
Brain Stimulation for Fibromyalgia Pain Relief
This study tests whether a non-invasive brain stimulation technique (called TMS) can help reduce pain and improve mood in women with fibromyalgia. Researchers will use MRI scans and brain stimulation to understand how pain and reward circuits in the brain work.
Durham, North CarolinaAges 18 years+ - NCT04918329Recruiting
Digestive symptom check-in study for adults
This study follows adults with long-lasting “functional” digestive symptoms as part of routine care. It may help researchers better understand these conditions and improve how they are managed.
RouenAges 18 years+ - NCT06161805RecruitingPhase 3
Esketamine for chronic pain from endometriosis
This trial tests if esketamine, a nasal spray, can reduce chronic pelvic pain in women with endometriosis that hasn't improved with standard painkillers. You may qualify if you have severe pain and are scheduled for endometriosis surgery.
DelftAges 18–50 - NCT07756203Recruiting
Comparing two hand-held treatments for shoulder pain
This study tests two non-surgical treatments for shoulder pain caused by shoulder impingement. Both treatments use hand-held tools to ease pain and improve movement.
Istanbul, BeykozAges 40–60 - NCT07525921Recruiting
Dry Needling for Calf Pain in Amateur Football Players
This study tests whether dry needling—inserting thin needles into tight muscle knots in the calf—can reduce pain and improve running speed and performance in young football players. Researchers want to see if this treatment helps athletes play better and feel less discomfort.
Islamabad, Punjab ProvinceAges 18–25 - NCT06757491Recruiting
Low frequency brain stimulation for diarrhea-predominant IBS pain
This trial tests if a type of brain stimulation called low-frequency repetitive transcranial magnetic stimulation (lf-rTMS) can reduce belly pain in people with irritable bowel syndrome that causes diarrhea (IBS-D). It is a non-invasive treatment that uses magnetic pulses to target areas of the brain involved in pain perception.
Suzhou, JiangsuAges 18–75 - NCT07313280Enrolling by invitation
PTSD and chronic pain therapy study for women
This study looks at how a psychological program can help women with chronic pain conditions linked to central sensitization (where the nervous system stays on high alert) and PTSD. It aims to reduce pain and stress symptoms.
Málaga, MálagaAges 18–65 - NCT05868668Recruiting
Low-intensity shockwave versus wave therapy for erectile and pelvic pain
This trial compares two types of low-intensity wave therapy to see which works better for erectile dysfunction and/or chronic pelvic pain. Participants may benefit if these therapies improve erection quality and reduce pelvic pain.
Cleveland, OhioAges 40 years+ - NCT07429773Recruiting
Immune markers in stubborn pelvic pain
This study looks at the immune system's response in people with chronic pelvic pain that hasn't gotten better with first treatments. By measuring certain immune markers, the researchers hope to better understand why the pain persists and find new ways to help.
Nice, Alpes-MaritimesAges 18–40 - NCT07807852Recruiting
Shock wave therapy for CRPS after wrist fracture
This trial tests whether sound wave therapy (ESWT) can reduce pain from a chronic pain condition called Complex Regional Pain Syndrome (CRPS) that started after a wrist fracture. It might help reduce pain and improve recovery.
Istanbul, IstanbulAges 18–75 - NCT07210515RecruitingPhase 3
Testing Ambros Therapy for Early CRPS
This trial tests if an intravenous medicine called AMBTX-01 (neridronate) can help people with early-stage Complex Regional Pain Syndrome (CRPS) type 1. It focuses on those whose affected limb feels warm, looks red, and is swollen.
Phoenix, ArizonaAges 18 years+ - NCT04845217RecruitingPhase 1/Phase 2
Peppermint oil for bladder pain in women
This trial tests whether peppermint oil can reduce symptoms of interstitial cystitis (also called bladder pain syndrome). It’s mainly looking at safety and early signs it may help your bladder discomfort.
Louisville, KentuckyAges 18–65 - NCT06294951Recruiting
Brain Scans for Bladder Pain Syndrome
This study uses brain scans (fMRI) to learn how bladder pain syndrome affects the brain. It compares women with bladder pain to those without, to better understand symptoms and improve future treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07811362Recruiting
Tracking long-term outcomes for CRPS after neridronate treatment
This study is a registry that tracks people with Complex Regional Pain Syndrome (CRPS) who already received neridronate infusions in a previous trial. It looks at how they do over the long term to learn more about the treatment's lasting effects.
Durham, North CarolinaAges 18 years+ - NCT07777081Recruiting
How your brain and body recover after a wrist fracture
This study looks at how your brain and body heal after a wrist fracture. By joining, you'll help doctors understand recovery better, which could improve care for future patients.
Cambridge, CambridgeshireAges 18 years+ - NCT07744269Recruiting
Hand therapy for early complex regional pain syndrome
This trial compares two hand therapy techniques — contrast baths (alternating warm and cool water) and compression with whirlpool therapy — to see which better eases early-stage complex regional pain syndrome (CRPS) after a hand or wrist injury. If you've had hand or wrist trauma and are still in pain, this study might help you find a treatment that reduces discomfort and improves hand use.
Ankara, YenimahalleAges 18–80 - NCT05279963Recruiting
Study for bladder pain using a nerve-based treatment (EA)
This trial tests whether a nerve-based therapy called EA can reduce bladder pain. It also aims to understand why the treatment may help by looking at underlying mechanisms.
Hangzhou, ZhejiangAges 18–70 - NCT07587931Recruiting
Concentric vs Eccentric Exercise for Partial Rotator Cuff Tears
This study compares two types of shoulder exercises—one where you shorten the muscle and one where you lengthen it—to see which works better for partial tears of your rotator cuff (the muscles that stabilize your shoulder). The goal is to reduce pain and improve shoulder function.
Elâzığ, MErkezAges 18–65 - NCT06719232Recruiting
Testing a new way to give bladder treatment without a catheter
This study tests a catheter-free method for delivering medication directly into the bladder. It may help patients with bladder pain, recurrent infections, bladder cancer, or cystitis after radiation or chemotherapy.
BudapestAges 18–80 - NCT06736756Recruiting
Stretching hip muscle to help with knee pain
This trial tests if stretching the tensor fascia lata muscle (near your hip) changes how the muscle on the inside of your kneecap works. It is for people who have front knee pain without a specific injury, especially when doing things like running, squatting, or climbing stairs.
CairoAges 18–30 - NCT06644261RecruitingPhase 4
Comparing two methods of nerve block for pelvic pain
This study compares two ways to give a pudendal nerve block—one through the vagina, one through the buttock with X-ray guidance—to see which works better for women with pudendal neuralgia (nerve pain in the pelvic area). It may help find a more effective and comfortable treatment option.
Louisville, KentuckyAges 18 years+ - NCT07472842Recruiting
Study on outcomes for endometriosis in emergency care
This study follows women who come to a specific hospital's emergency department with known endometriosis or symptoms that might be endometriosis, to learn more about their health outcomes over time.
CréteilAges 18 years+ - NCT07459790RecruitingPhase 2/Phase 3
A new treatment for interstitial cystitis with Hunner's lesions
This study tests a new treatment for women with interstitial cystitis (also called painful bladder syndrome) who have Hunner's lesions (specific sores in the bladder lining). The goal is to see if the new treatment can reduce pelvic pain, frequent urination, and other symptoms.
MoscowAges 18–65
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Common questions
- Are there clinical trials for pain syndrome?
- Yes. Clin2 currently lists 267 recruiting pain syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.