Clinical trials
Pain Syndrome clinical trials
Below are recruiting pain syndrome clinical trials, each written for real people, not researchers. We’re tracking 267 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06472622RecruitingEarly Phase 1
Brain imaging study of pain and effort
This study uses brain scans to understand how people experience pain and effort. It compares healthy volunteers to people with ME/CFS to see if there are differences in brain activity.
Bethesda, MarylandAges 18–50 - NCT05172739RecruitingPhase 4
Opioid-free anesthesia during lung surgery for early lung cancer
This study tests whether an opioid-free pain/anesthesia plan during elective lung surgery can reduce surgical “stress” on the body and affect the immune system. You may be eligible if you have early-stage non-small cell lung cancer and are scheduled for a specific type of surgery (VATS lobectomy).
Heraklion, CreteAges 18–80 - NCT04709900Recruiting
Tests for stable chest pain using heart scans and pressure measurements
This trial studies how well different heart tests (imaging the blood flow and measuring blood pressure in the heart) work for people with stable chest pain. It may help guide safer, more accurate evaluation when you are not having a heart attack.
CopenhagenAges Any age - NCT07556952RecruitingPhase 4
Dexamethasone to reduce pain after breast removal surgery
This study tests whether dexamethasone (a common anti-inflammatory medication) can reduce pain after mastectomy (surgical removal of breast tissue). Researchers want to see if it helps patients recover with less pain and potentially fewer pain medications.
Montreal, QuebecAges 18–75 - NCT06418217Recruiting
Exercise and education for lateral hip pain
This study tests whether exercise and patient education can help people with long-term lateral hip pain (pain on the outside of the hip). If you've had hip pain for over 6 months and an MRI confirms the cause, you may be able to join.
Horsens, HorsensAges 18–75 - NCT06212661Enrolling by invitation
Study on migraine drugs and bladder symptoms
This study looks at how certain migraine treatments affect bladder symptoms like frequent or urgent urination. If you have hard-to-treat migraines and are starting a CGRP inhibitor or Botox injections, you may be able to join.
Cleveland, OhioAges 18 years+ - NCT07180407Recruiting
Post-ICU pain study for adults
This study looks at pain after a stay in the intensive care unit (ICU). It aims to understand pain in patients who were urgently admitted to the ICU and stayed for at least two days.
AalborgAges 18 years+ - NCT07488936Recruiting
How low back pain types affect pain and quality of life after failed back surgery
This study looks at how different types of low back pain affect pain severity and quality of life in people who still have pain after back surgery. It aims to help doctors better understand and treat your pain.
Konya, SelçukluAges 18 years+ - NCT07211308Recruiting
A study of spinal cord stimulation for chronic leg pain
This trial tests a type of spinal cord stimulation (DTM SCS) for people with chronic leg or foot pain caused by nerve damage (PSPS-T2). It aims to see if this treatment can safely reduce pain and improve daily life.
BrusselsAges Any age - NCT05767619Recruiting
Digital tool to guide care for chest pain calls
This trial tests a digital decision-support tool that helps emergency teams manage people who call for help because of chest pain. It may improve how safely and consistently chest pain is assessed and treated in the ambulance setting.
Kungsbacka, Region HallandAges 18 years+ - NCT07526012Recruiting
Stretching techniques for buttock pain from pinched nerve
This study compares two stretching methods to treat piriformis syndrome, a condition where a muscle in your buttock pinches a nerve. The trial tests whether one stretching approach works better than the other for reducing pain.
Islamabad, Punjab ProvinceAges 20–55 - NCT07192965Recruiting
Heart scan without ECG for chest pain with high troponin
This trial tests if a coronary CT scan (without needing an ECG) can safely guide care for people who come to the emergency room with chest pain and a high troponin level. It aims to see if this approach works as well as standard tests.
JetteAges 30 years+ - NCT06209346Recruiting
Remote physical therapy for chronic pelvic pain from endometriosis
This trial tests if a physical therapy program done at home through video calls can help reduce chronic pelvic pain in people with endometriosis. If you have ongoing pelvic pain and have already had medical or surgical treatment, this study may offer a new way to manage your pain.
Alcalà de Henares, MadridAges 18–55 - NCT06481072Recruiting
Digital therapy for kids with chronic stomach pain
This trial tests a digital (online) therapy program to help children with chronic stomach pain. It's designed for kids ages 8 to 14 who have been diagnosed with a functional abdominal pain disorder and can use a computer or tablet at home.
GothenburgAges 8–14 - NCT06816095Recruiting
Ozone therapy for pelvic pain after gynecological cancer treatment
This study is looking at whether ozone therapy can help relieve chronic pelvic pain caused by gynecological cancer treatments like radiation and chemotherapy. It aims to understand how the treatment works at a molecular level.
Las Palmas, Las PalmasAges 18 years+ - NCT05269212Recruiting
Help people with ongoing back pain return to work
This study looks at how to help people with long-lasting spinal pain (PSPS-Type II) get back to work. It may help by testing a plan for managing persistent pain so work becomes more doable.
GhentAges 18–60 - NCT07183774Recruiting
Does muscle loss affect shoulder tear patterns?
This study looks at whether sarcopenia (age-related muscle loss) affects the type of rotator cuff tear you have. You'll get a shoulder MRI to check your rotator cuff and muscle measurements.
Istanbul, ÜsküdarAges 40–75 - NCT05023005Recruiting
Strain-Counterstrain therapy for piriformis muscle pain
This trial tests a hands-on physical therapy technique called “strain-counterstrain” to reduce pain from the piriformis muscle. It may help people whose pain is coming from that specific muscle rather than the low back.
Loma Linda, CaliforniaAges 18–65 - NCT06847360Recruiting
Home-based ear stimulation for IBS pain
This trial tests a gentle, non-invasive ear stimulation device (taVNS) used at home to reduce pain from Irritable Bowel Syndrome (IBS). It might help if you have moderate pain most days.
New Haven, ConnecticutAges 18–29 - NCT05946850Recruiting
Caudal pain block study for adults with chronic pain
This trial looks at giving a specific pain procedure called caudal analgesia to adults with long-term (chronic) pain. It may help reduce pain after the procedure, and it will compare results for people who can safely receive it.
Surrey, British ColumbiaAges 20–99 - NCT07640126Recruiting
Acupuncture for cold-sensitive neck pain
This trial tests whether a specific type of acupuncture (three-needle Dazhui plus electroacupuncture) can reduce pain and improve function in people with neck pain caused by cervical spondylosis, especially when the pain is worse in cold weather. It combines a modern diagnosis with traditional Chinese medicine ideas to see if this approach helps more than standard care.
Ho Chi Minh CityAges 3 weeks+ - NCT05730491Recruiting
Online parenting program for kids with IBS-related belly pain
This trial tests an online social learning program to help parents support their child when the parent has irritable bowel syndrome (IBS) or related belly pain. It may help families build coping skills and resilience through guided parent sessions.
Seattle, WashingtonAges 18 years+ - NCT05513417Enrolling by invitation
Digital pelvic health program for women with pelvic pain
This study tests a digital (phone/app-based) program to help women with pelvic pain or pelvic health symptoms. It may help by guiding pelvic-focused exercises and care, especially if you’re recovering from pelvic surgery or managing ongoing symptoms.
Draper, UtahAges 18–99 - NCT05277025Recruiting
Brain pain testing in long-term joint pain and fibromyalgia
This study looks at how the brain processes pain in people with long-term pain conditions like fibromyalgia and rheumatoid arthritis. You may be asked to undergo pain-related tasks to help researchers understand differences between inflammatory and non-inflammatory chronic pain.
Gainesville, FloridaAges 18–70
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Common questions
- Are there clinical trials for pain syndrome?
- Yes. Clin2 currently lists 267 recruiting pain syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.