Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03987334Recruiting
Virtual reality rehab for chronic neck pain
This trial studies whether virtual reality exercises can help reduce pain and improve function in people with chronic neck pain or whiplash. You may be invited to take part in guided VR rehab sessions if you meet the safety and health requirements.
Milan, MIAges 18–70 - NCT04046562Recruiting
Testing a teen pain-and-weight program
This trial studies a program meant to help teens manage weight when they also have ongoing muscle or joint pain. It may help by targeting pain feelings and supporting healthier weight habits at the same time.
Hartford, ConnecticutAges 12–18 - NCT04081896Recruiting
Rehab program for adults with spine pain
This trial studies whether a prescribed physical therapy (rehab) program helps people with spine pain. It may help by improving pain and function when a clinician has already recommended rehabilitation.
San Diego, CaliforniaAges 18–89 - NCT04142177Recruiting
Test which pain treatments work best for chronic low back pain
This study compares how well different pain treatments reduce low back pain and improve daily life. You may be asked to start or continue care through the VA and attend in-person sessions while completing pain and activity questionnaires.
Phoenix, ArizonaAges 18 years+ - NCT04226716Recruiting
Studying pelvic pain causes in multiple or first pregnancies
This study looks at why pelvic girdle pain happens during pregnancy, focusing on body sensing (proprioception), stress factors, and inflammation. You may be able to help researchers understand the causes and who is most at risk.
HasseltAges 18–40 - NCT04439552Recruiting
MRI study during cornea cross-linking for keratoconus
This trial uses an MRI scan (and a close-up eye scan) to study what happens in the cornea during treatment for keratoconus. It may help doctors better understand how treatment works and who benefits most.
Boston, MassachusettsAges 8–35 - NCT04673981Recruiting
Follow-up study for oral and throat cancer pain
This study looks at nerve-related symptoms and pain in the mouth and throat in people who have been treated for oral or oropharynx cancer. You may be able to take part if you’re within 1 to 5 years after treatment and can follow study steps.
Clermont-FerrandAges 18 years+ - NCT04689646Recruiting
Mind-body therapy for chronic back pain
This study tests whether a mind-body therapy approach can reduce disability and how bothersome chronic back pain feels. It may help people whose pain has lasted for months and affects daily life.
Boston, MassachusettsAges 18–67 - NCT04699734Recruiting
Nerve block for nerve pain from diabetes
This trial studies whether a numbing “nerve block” can reduce long-lasting nerve pain caused by diabetic neuropathy. You may keep your usual pain medicines, and the study will mainly check whether you fit the safety and diagnosis criteria.
Aarhus N, JutlandAges 18 years+ - NCT04898491Recruiting
Pain behavior scale study for adults who cannot speak
This study checks whether a “pain behavior” checklist works well and gives consistent results in adults who can’t communicate verbally and who have an artificial airway. It may help clinicians better recognize pain in people who cannot tell them directly.
Madrid, MadridAges 18 years+ - NCT04907643Recruiting
Virtual reality program to reduce stomach-cancer pain
This trial tests whether virtual reality (VR) can improve pain and other day-to-day symptoms in people with certain gastrointestinal cancers. You’d use VR for pain relief while researchers measure how you’re feeling.
Los Angeles, CaliforniaAges 18–99 - NCT04923477Recruiting
Exercise study for shoulder tendon pain and pinching
This trial studies a specific therapeutic exercise program for rotator cuff tendon pain and subacromial pain (a pinching-type shoulder problem). It also looks at what changes in your symptoms and body function after the exercises.
Los Angeles, CaliforniaAges 18–55 - NCT04267588Recruiting
Using technology to track your chronic pain
This trial uses technology to follow how your pain changes over time and how it affects your daily life. It may help researchers understand pain patterns and improve pain care, as long as you can safely and consistently take part.
Baltimore, MarylandAges 21 years+ - NCT06101303Recruiting
Endometriosis pain study using surgery and surveys
This study looks at pain in people with or without endometriosis who are having laparoscopic surgery. Researchers want to understand more about pelvic pain by collecting information before, during, and after surgery.
St Louis, MissouriAges 12–45 - NCT05009459Recruiting
App-based program to help chronic pain and daily activity
This study tests an eVIS tool that combines information about physical activity and pain to help people with long-lasting pain improve how pain affects daily life. You may be a good fit if you have chronic pain and can complete the program in Swedish using your own device.
FalunAges 18–67 - NCT05034835Recruiting
Compression garments for arm nerve pain in CRPS
This study tests whether wearing a special compression sleeve or garment can reduce pain in people with complex regional pain syndrome (CRPS) affecting the arm. It’s looking at pain changes while making sure it’s safe for your skin and blood flow.
Ploemeur, Brittany RegionAges 18 years+ - NCT05052541RecruitingPhase 3
Oral cannabis for long-term spine pain
This trial studies whether taking cannabis by mouth can safely reduce chronic spine pain and improve daily comfort. You may be eligible if you have long-lasting spine pain and can follow study rules about stopping or limiting other cannabis and certain other treatments.
Aurora, ColoradoAges 21–84 - NCT05146778Recruiting
Opioid-free anesthesia to reduce long-term post-mastectomy pain
This study tests whether a pain-control approach without opioids (strong pain medicines) can lower persistent pain after mastectomy. It may help people avoid long-term pain and opioid side effects.
SeoulAges 19–80 - NCT05147948Recruiting
Online therapy for PTSD plus chronic pain symptoms
This trial tests an iACT program (a structured, online skills-based therapy) for people who have both PTSD symptoms and chronic pain that affects daily life. It may help you learn ways to better handle distress and improve everyday functioning.
LundAges 18–65 - NCT05193227RecruitingPhase 2
Slow-release lidocaine patch for pain after pelvic surgery
This Phase 2 study tests a slow-release form of lidocaine to reduce pain after surgery that uses a pelvic incision. If you’re having a qualifying pelvic operation, the study may help see whether this medication improves postoperative pain control.
Vancouver, British ColumbiaAges 19 years+ - NCT05196503RecruitingPhase 3
PRF gel in spine surgery to reduce nerve pain after herniation
This Phase 3 study tests whether applying a healing material called platelet-rich fibrin (PRF) around the nerve during disc herniation surgery can reduce leftover nerve pain afterward. If you qualify, your team will compare pain intensity between standard care and PRF during the operation.
Strasbourg, Bas-RhinAges 18 years+ - NCT05204472Recruiting
Deep brain stimulation for ongoing nerve pain after stroke or facial nerve issues
This trial studies whether a special brain device (deep brain stimulation, or DBS) can reduce long-lasting nerve pain. It focuses on one-sided pain after certain brain injuries or specific facial nerve pain causes, especially when medicines haven’t helped enough.
BernAges 18–75 - NCT05220202Recruiting
Program for older vets with pain and depression
This trial tests a non-medicine (non-pharmacologic) home program to help older Veterans manage musculoskeletal pain and depressive symptoms at the same time. You may be assigned to one of two approaches, and you’ll need to be able to take part from home.
Dallas, TexasAges 60–99 - NCT05323383Recruiting
Brief mindfulness and hypnosis for ongoing pain relief
This trial studies whether brief mindfulness meditation or hypnosis can help people who live with long-lasting or recurring pain. It also looks at how these approaches might reduce pain over time.
Brisbane, QueenslandAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.