Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
Birmingham, AlabamaAges 18 years+ - NCT06835608Recruiting
Schroth exercise for kyphosis and chronic neck pain
This study tests whether an exercise program called Schroth (which strengthens back muscles) can improve your posture, reduce neck pain, and make daily activities easier. It is for people with a hunched upper back (kyphosis) and long-lasting neck pain.
Ankara, ÇankayaAges 20–50 - NCT07065266Enrolling by invitation
Pain survey for ACL knee surgery patients
This trial is testing a simplified pain questionnaire for people who are having ACL knee surgery. The goal is to see if this shorter questionnaire can effectively measure pain levels after surgery.
Redwood City, CaliforniaAges 18 years+ - NCT06929559Recruiting
How the body responds to walking when expecting pain
This study looks at how your muscles and walking pattern change when you expect a mild pain. It may help researchers understand how the body adapts to pain anticipation in healthy people.
AmiensAges 18–35 - NCT06175884Recruiting
Communication skills for chronic muscle and joint pain
This trial tests how a physical therapist's communication style affects pain and function in people with long-term muscle or joint pain. Participants will fill out questionnaires and watch a video to see if better communication improves outcomes.
LamiaAges 18–65 - NCT06485856Recruiting
Pain tracking using facial movements for non-verbal patients
This trial tests a system that measures facial movements to assess pain in patients who cannot speak or communicate verbally, such as those with a breathing tube. It may help healthcare providers better understand and manage pain in these patients.
AdanaAges 18 years+ - NCT07723001Recruiting
Mobilization for neck pain relief and function
This trial tests if moving the neck and upper back joints can reduce pain and improve daily life for people with nagging neck pain (lasting more than 4 weeks). It aims to find a simple hands-on treatment to help you feel better and move easier.
Lahore, Punjab ProvinceAges 20–40 - NCT07148921Recruiting
Pain perception during gender affirming hormone therapy
This study looks at how starting gender affirming hormone therapy may change your experience of pain. If you are an adult assigned female at birth planning to start testosterone, or an adult assigned male at birth planning to start estradiol, and you have not taken any sex hormones in the past six months, this trial wants to measure your pain perception over time.
Vienna, State of ViennaAges 18 years+ - NCT06671925Recruiting
Support program for chronic pain and loneliness in older adults
This trial tests a program led by community health workers to help older adults manage chronic pain and reduce loneliness. It aims to improve your well-being through support and guidance.
Ann Arbor, MichiganAges 60 years+ - NCT06001749RecruitingPhase 2
Psilocybin for cancer pain study
This trial tests whether psilocybin (a psychedelic drug) can help with severe cancer pain. You may qualify if your pain is high despite strong medications and you are willing to be monitored closely.
Boston, MassachusettsAges 18 years+ - NCT07743073Recruiting
Ceylon cinnamon for diabetic nerve pain
This study tests whether taking Ceylon cinnamon daily can help lower blood sugar, improve cholesterol, and reduce nerve pain in adults with type 2 diabetes and painful diabetic peripheral neuropathy. If you qualify, you might get a natural supplement that could ease your symptoms.
AmmanAges 18 years+ - NCT07742111Recruiting
Virtual reality for long-term low back pain
This study tests whether virtual reality exercises can help people with chronic low back pain feel better and move more comfortably. You might join if you have had low back pain for a while, your pain is moderate, and you have some fear of movement.
AmaranteAges 18 years+ - NCT07742228Recruiting
SCENAR therapy for long-term neck pain
This study tests a device called SCENAR that uses gentle electrical signals to help reduce chronic neck pain. It may be an option for people whose neck pain has lasted at least 3 months and who have not found relief with other treatments.
Suresnes, Île-de-France RegionAges 18–80 - NCT05563792Recruiting
Non-drug options for managing chronic pain
This study tests non-drug treatments for chronic pain in the back, neck, or joints. It aims to help people manage pain and improve daily function without relying on medications.
Indianapolis, IndianaAges 18 years+ - NCT07386548Recruiting
Biologic injection for low back disc problems
This study tests if an injection can help people with a herniated disc in the lower back who have not gotten better with other treatments and are already planning surgery. It aims to see if the injection can reduce symptoms and possibly avoid or improve surgery outcomes.
Manhattan, New YorkAges 18 years+ - NCT07494734Enrolling by invitation
Manual therapy for neck pain, disability, and quality of life
This study tests whether manual therapy (hands-on techniques) can reduce neck pain, improve daily function, and enhance quality of life for people with long-term neck pain.
Kocaeli, GebzeAges 18–65 - NCT07278804Recruiting
Pain control options for IUD insertion
This study tests different pain control choices during IUD placement. It may help you find what works best for your comfort.
Durham, North CarolinaAges 18–50 - NCT07713108Recruiting
Pelvic floor muscle function and endometriosis pain study
This study looks at how pelvic floor muscles work in women with endometriosis-related pelvic pain compared to healthy women. It aims to understand if muscle function is linked to pain, which could help improve treatments.
Pécs, BaranyaAges 18–48 - NCT07712211Recruiting
Pain Catastrophizing and Nausea After Gallbladder Surgery
This study looks at how a person's tendency to focus on and feel overwhelmed by pain (called 'pain catastrophizing') might affect nausea and vomiting after gallbladder surgery. If you are scheduled for keyhole gallbladder removal, you may help doctors better predict and prevent post-surgery nausea.
TrabzonAges 18–65 - NCT06386224Recruiting
Online pain self-management for pancreatitis pain
This study tests an online pain-management program for adults with chronic or recurrent acute pancreatitis. The program is done on your own device (or a loaner iPad) and is designed to help you learn skills to cope with pain and improve daily life.
Seattle, WashingtonAges 18 years+ - NCT06171659Recruiting
PET/MRI scan to find pain sources after joint surgery
This study uses a special type of scan called PET/MRI to look for areas in the body that may be causing ongoing pain after joint replacement or arthroscopy. It aims to better understand why some people have pain that lasts months after surgery.
Madison, WisconsinAges 18–85 - NCT03258580Recruiting
Studying how culture and mind affect how we feel pain
This study looks at how beliefs, mood, and social factors affect how people express and judge pain. It mainly uses pain/heat testing and—if chosen—brain scans to understand why pain reports can differ between people.
Bethesda, MarylandAges 18–60 - NCT03675386Recruiting
Help reducing opioid use after surgery for chronic pain
This trial tests a program to help people with long-term (chronic) pain use less opioid medicine after surgery. It may help you reduce opioid doses while still managing your pain.
Toronto, OntarioAges 18 years+ - NCT03829631Recruiting
Test of a back brace for non-dangerous low back pain in ER
This trial studies whether using a lumbar brace in the emergency department helps people with non-serious low back pain recover better. You may be asked to try the brace when you come to the ER for back pain that is not caused by a dangerous underlying condition.
PerthAges 18–65
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.