Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,138 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07257029RecruitingPhase 2
Ketotifen Cream for Vulvar Pain
This trial tests a topical cream called ketotifen for treating a type of vulvar pain (secondary provoked vestibulodynia). The cream may help reduce pain at the vaginal opening, and you would apply it daily for several months.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07250230Recruiting
Nicotine patch for pain after lung surgery in male smokers
This study tests if a high-dose nicotine patch worn before and after lung surgery can reduce pain in men who smoke but are quitting for the procedure. It aims to help manage pain during recovery.
Zhengzhou, HenanAges 18–75 - NCT07256691Recruiting
Bioceramic vs. resin sealer for root canal pain
This study tests two types of sealing materials used in root canals (a newer bioceramic one vs. a standard resin one) to see which causes less pain after treatment. If you have an infected, pain-free tooth that needs a root canal, this trial may help guide better care.
Lahore, Punjab ProvinceAges 18–55 - NCT07256145Recruiting
Ultrasound-guided nerve block for post-shingles pain
This study compares a new ultrasound-guided nerve block (erector spinae plane block) with standard care to help manage stubborn nerve pain after shingles. It might be an option if usual medications havent helped your pain.
Alexandria, AleexandriaAges 20–70 - NCT07242573Recruiting
Exercise and brain stimulation for fibromyalgia
This study tests if combining physical exercise with a gentle brain stimulation technique can improve pain, sleep, and fatigue in people with fibromyalgia.
Warsaw, Masovian VoivodeshipAges 20–80 - NCT07244029Recruiting
Herbal extract for pain and swelling after wisdom tooth surgery
This trial tests if an herbal extract called Reparil (aescin) can reduce pain, swelling, and stiffness after impacted wisdom tooth removal. It compares Reparil to a standard pain reliever (ibuprofen) to see which works better for recovery.
Muscat, Al KhoudAges 18–40 - NCT07241884Recruiting
Plantar fascia embolization with SakuraBead for heel pain
This trial tests a new treatment for plantar fasciitis using tiny beads (SakuraBead) that are injected to block abnormal blood vessels and reduce pain. It may help people with chronic heel pain that hasn't improved with other treatments.
Tashkent, UzbekistanAges 18–75 - NCT07247669Recruiting
AI phone triage for emergencies
This study tests if artificial intelligence can help identify time-sensitive emergencies like stroke, heart attack, or trouble breathing from recorded phone calls. The goal is to make emergency response faster and more accurate.
Málaga, MálagaAges Any age - NCT07242170Recruiting
Comparing nerve blocks for pain after knee replacement surgery
This trial tests if adding extra nerve blocks (sciatic, BiFeS, or IPACK) to the usual adductor canal block can reduce pain after total knee replacement. The goal is to find a better way to manage pain and improve recovery.
Erzincan, MerkezAges 18–75 - NCT07244068Recruiting
Mat Pilates for kids with upper crossed syndrome
This trial tests if Mat Pilates can reduce pain and improve posture in school-going children with a specific forward head and rounded shoulder condition called upper crossed syndrome. It may help your child feel better and stand straighter.
Lahore, Punjab ProvinceAges 8–16 - NCT07243587Recruiting
Study of endometriosis affecting the bowel
This study observes women with deep endometriosis that affects the colon or rectum to better understand the condition and improve treatment. Your participation will help researchers learn more about this type of endometriosis.
BordeauxAges 18 years+ - NCT07248475Recruiting
Battle rope training for elbow pain and stiffness after injury
This study tests whether battle rope exercises can help children ages 8–15 with elbow stiffness and pain after an injury. It aims to improve movement and reduce discomfort.
Lahore, Punjab ProvinceAges 8–15 - NCT07241949Recruiting
Nerve block for gallbladder surgery pain relief
This study tests a nerve block called the external oblique intercostal block to reduce pain after laparoscopic gallbladder removal. If you are having this surgery, the block may help you need less pain medication and feel more comfortable after the procedure.
AdanaAges 18–65 - NCT06788314RecruitingPhase 2
Enalapril for painful venous malformations
This trial tests if the blood pressure drug enalapril can reduce pain from venous malformations (abnormal veins). It may help people whose pain limits daily activities or interrupts sleep.
Oslo, NorwayAges 18–70 - NCT07233538Recruiting
Numbing injection before nose surgery for better pain relief
This study tests a numbing injection in the cheek area before septorhinoplasty to see if it improves pain control and reduces the need for strong IV pain medicine. It may help you have a smoother recovery with less discomfort.
Ankara, YenimahalleAges 18–65 - NCT07235982Recruiting
Shoulder block plus steroid vs. steroid alone for frozen shoulder pain
This trial compares two treatments for frozen shoulder (adhesive capsulitis): a steroid injection alone versus a steroid injection plus a nerve block. The goal is to find which approach provides better pain relief for people who have not improved after two weeks of conservative care.
ZagazigAges 41–65 - NCT07236658Recruiting
Using AI to detect arm problems after breast cancer surgery
This trial uses artificial intelligence (a computer program) to help predict arm and shoulder problems that can happen after breast cancer surgery. It aims to find these issues early so they can be treated better.
AnkaraAges 18 years+ - NCT07238595Enrolling by invitation
Neck Pain and Body Awareness in Healthy Older Adults
This study looks at how neck pain relates to your body's ability to sense where your neck is in space (proprioceptive awareness). It is for healthy older adults who can live independently and want to help researchers understand this connection.
IspartaAges 65 years+ - NCT07239700Enrolling by invitation
Buzzy and TickleFlex for easier insulin shots in kids
This study tests two devices, Buzzy and TickleFlex, to see if they can reduce pain and fear during insulin injections in children with type 1 diabetes. It may help make daily injections more comfortable.
Hakkari, CentreAges 6–12 - NCT07239817Recruiting
Nerve block and local anesthetic for hip replacement surgery
This study tests whether a nerve block plus local anesthetic can improve pain control during and after hip replacement surgery for a broken hip. It may help reduce the need for stronger pain medications and improve recovery.
MilanAges 18 years+ - NCT07235098Recruiting
Music therapy for lung cancer surgery patients
This trial tests whether listening to music in the hospital can help reduce distress and pain after surgery for lung cancer. If you are having a minimally invasive surgery (keyhole surgery) to remove part of your lung, you may be able to join.
Bellinzona, Canton TicinoAges 18 years+ - NCT07232108Recruiting
Pain medicine options for recovery after laparoscopic hysterectomy
This study compares two types of pain medicine given during laparoscopic hysterectomy: one is a morphine shot into the spine, the other is numbing medicine injected around the surgery cuts and into the belly. The goal is to see which helps you recover better and with less pain.
ErzurumAges 18–65 - NCT06863636RecruitingPhase 3
Combination painkiller vs celecoxib for osteoarthritis flare-ups
This study tests whether a combination of two pain relievers (celecoxib and acetaminophen) works better than celecoxib alone for sudden, severe osteoarthritis pain in the knee or hip.
Mexico CityAges 40 years+ - NCT07221786Recruiting
Opioid reduction before spine surgery
This trial tests whether slowly reducing opioid pain medications before spine surgery can lead to a better recovery afterward. It is for adults already taking daily opioids who have major spine surgery planned at least a month away.
Philadephia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,138 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.