Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06415890Recruiting
4-7-8 breathing for shoulder pain after gallbladder surgery
This study tests whether a simple breathing technique (called 4-7-8 breathing) can help reduce shoulder pain and improve breathing after gallbladder removal surgery. It may be a good fit if you are having planned laparoscopic gallbladder surgery and staying overnight in the hospital.
HatayAges 18 years+ - NCT06418958Recruiting
Heat from dental light on healthy teeth
This trial measures how much the temperature rises inside a healthy tooth when a dental curing light is used. It helps dentists understand if certain light wavelengths could be safer for teeth.
Gainesville, FloridaAges 21–35 - NCT06419842Recruiting
Hypnosis for lumbar infusion test comfort
This trial tests whether hypnosis can help make a lumbar infusion test (a procedure to check for normal pressure hydrocephalus) more comfortable. It's for adults 65 and older who are already scheduled for this test.
Amiens, PicardieAges 65 years+ - NCT06424743Recruiting
Strength training volume for women with fibromyalgia
This study tests whether different amounts of strength training (resistance exercise) help women with fibromyalgia feel better. It compares three different workout volumes to see which one women prefer and which works best for their symptoms.
Natal, Rio Grande do NorteAges 18–65 - NCT06425016Recruiting
Robot-assisted vs. traditional sleeve gastrectomy
This study compares two types of weight-loss surgery: one done with the help of a robot and the other done by hand (laparoscopic). Both are types of sleeve gastrectomy, where the stomach is reduced in size. If you qualify for sleeve gastrectomy, this trial may help doctors learn which method works better.
Cleveland, OhioAges 18–70 - NCT06426251Recruiting
Light therapy for knee replacement recovery
This trial tests whether a special light therapy (photobiomodulation) can help reduce pain and speed healing after total knee replacement. If you're having knee replacement and don't have complications like infection or open wounds, you may be eligible.
HsinchuAges 20 years+ - NCT06426316Recruiting
Immune cells and migraines study
This study looks at how certain immune cells and inflammatory chemicals relate to migraines. If you have migraines or an autoimmune condition (like lupus, rheumatoid arthritis, or Crohn's disease), you may be able to participate. The goal is to understand what causes migraines.
Clermont-Ferrand, AURAAges 18–50 - NCT06427356Recruiting
Team care for veterans with chronic pain at Salem VA
This study tests a team-based approach to help veterans with long-lasting pain. It looks at whether working with a group of specialists (like doctors, nurses, and mental health providers) can improve pain and daily life. It is for veterans already receiving care at the Salem VA who are part of the PREVAIL program.
Salem, VirginiaAges 18 years+ - NCT06429501RecruitingPhase 2
Numbing medicine for facial fracture surgery
This study tests numbing medicine (local anesthetic) given during surgery for broken facial bones, like the jaw or cheekbones. The goal is to see how well it works and if it helps recovery.
St Louis, MissouriAges 18 years+ - NCT06434233RecruitingPhase 4
Opioid use after fallopian tube removal surgery
This study looks at how much opioid pain medicine people need after having their fallopian tubes removed through small incisions (laparoscopic or robotic salpingectomy). It aims to see if the usual pain medicine can be reduced to decrease opioid use.
Baltimore, MarylandAges 18 years+ - NCT06444919RecruitingPhase 4
Capsaicin patch for finger osteoarthritis with nerve pain
This study tests if a capsaicin patch (a hot pepper extract) can reduce finger pain in people with osteoarthritis who also have nerve-like pain. It's for those who haven't gotten enough relief from standard painkillers.
Clermont-FerrandAges 18 years+ - NCT06446830Recruiting
Vitamin B complex for pain relief after cesarean in ICU
This trial tests whether adding vitamin B complex to standard pain medicine can improve pain control after a cesarean section in critically ill women. It aims to find a safer, effective way to manage pain without relying too much on strong opioids.
Cairo, EgyptAges Any age - NCT06446960RecruitingPhase 3
Nerve blocks for stroke-related central pain
This study tests whether numbing the nerves in your painful arm or leg (with a nerve block) can help reduce central pain after a stroke. It aims to find out how the nerves outside your brain and spinal cord may be involved.
Boulogne-BillancourtAges 18 years+ - NCT06448923RecruitingPhase 2
CBD for Pain and Opioid Reduction After Fracture
This trial tests if cannabidiol (CBD) can help reduce pain and the need for opioids after a broken arm or leg. If you recently broke a bone and are between 18 and 70, you might be able to join.
Montreal, QuebecAges 18–70 - NCT06453005Recruiting
Comparison of two tooth cap methods for baby molars
This trial compares two ways to fix cavities in baby molars: the SMART Hall technique (a newer, less invasive method) and the traditional stainless steel crown. The goal is to see which works better for children aged 3 to 9.
Tirupati, AndhrapradeshAges 3–9 - NCT06453109Recruiting
Focused ultrasound for chronic back pain with opioid use
This study tests whether focused ultrasound (a non-invasive treatment using sound waves) can help people with chronic back pain who also have opioid use disorder and anxiety. It aims to find a better way to manage pain without relying on opioids.
Washington D.C., District of ColumbiaAges 18–75 - NCT06453447Recruiting
Prednisone to prevent CRPS after wrist fracture surgery
This trial tests whether a short course of the steroid prednisone can prevent or reduce complex regional pain syndrome (CRPS) after wrist surgery. It is for people who had a broken wrist fixed with a plate and screws and have a higher chance of developing CRPS.
Vancouver, British ColumbiaAges 19 years+ - NCT06458478Recruiting
Gel to help healing after wisdom tooth removal
This trial tests a special gel applied after removing lower wisdom teeth to see if it helps healing. It is for healthy people who need both bottom wisdom teeth taken out.
PerugiaAges 18–35 - NCT06464146RecruitingPhase 3
Comparing nose and mouth pain medicines for broken bones in kids
This study compares three different fast-acting pain medicines given through the nose or by mouth to children with a suspected broken arm or leg in the emergency room. The goal is to find which medicine works best for pain relief within the first hour.
Boulogne-BillancourtAges 2–17 - NCT06469905Recruiting
Nerve block for pain from herniated disc
This study tests a nerve block injection (called an erector spinae plane block) to see if it helps reduce pain from a herniated disc in the lower back. It may be a good fit if you have ongoing low back pain and have not had spine surgery before.
ElâzığAges 18–65 - NCT06471426Recruiting
Osteopathic treatment for neck pain and headaches
This study tests whether a type of hands-on treatment called osteopathic manipulation can help relieve neck pain and headaches. It's for people who have had these symptoms for more than a month.
Auburn, AlabamaAges 19–65 - NCT06471517Recruiting
Nerve device for diabetic foot numbness
This trial tests a special device that uses mild electrical pulses to help improve problems caused by diabetic nerve damage, such as numbness and pain in the feet. If you have diabetic neuropathy and can walk on your own, this study may be a good option.
BelgradeAges 18 years+ - NCT06477796Recruiting
Improving sleep in veterans with TBI and sleep problems
This study tests a new way to help Veterans with both a traumatic brain injury (TBI) and sleep problems get better rest. If you are a Veteran with sleep trouble and a history of TBI, this program may help improve your sleep without needing extra medication.
Portland, OregonAges 18–89 - NCT06479122RecruitingPhase 4
Pain relief after C-section: acetaminophen with or without ibuprofen
This study compares two common pain relievers after C-section: acetaminophen alone versus acetaminophen plus ibuprofen. It aims to see if the combination offers better pain control after childbirth.
SeoulAges 19 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.