Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,138 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07282522Recruiting
Sensory and function in cervical disc herniation
This study looks at how cervical disc herniation affects sensation and daily function. If you have had neck pain for at least 3 months and have been diagnosed with cervical disc herniation, researchers want to compare your results to people without neck pain.
Iğdır, IğdirAges 18–65 - NCT07281118Recruiting
Nerve freezing for pain after double lung transplant
This trial tests a procedure called intercostal cryoanalgesia, which freezes nerves in the chest to reduce pain after a double lung transplant. It may help you feel less pain and use fewer painkillers after surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT06741059Recruiting
TENS for period pain relief
This study tests if TENS, a gentle electrical stimulation device, can reduce period pain and related symptoms. If you have painful periods and are not using other treatments, this might be an option for you.
OsmaniyeAges 18 years+ - NCT06762665Recruiting
Radiology consultation for spine injections
This study tests whether a radiology consultation before a CT-guided spine injection helps patients with back or neck pain. If you have moderate to severe pain and are scheduled for this procedure, you may be eligible.
Montpellier, OccitnaieAges 18 years+ - NCT06888791Recruiting
Hydro dissection for frozen shoulder: ultrasound vs X-ray guidance
This trial compares two ways to guide a fluid injection for frozen shoulder—one using ultrasound and one using X-ray. The goal is to see which technique works better to reduce pain and improve movement.
AnkaraAges 18–80 - NCT07274254RecruitingPhase 3
Lidocaine for sickle cell pain crisis in intensive care
This trial tests whether a numbing medicine (lidocaine) given through a vein can help reduce the amount of strong painkillers (morphine or oxycodone) needed for a sickle cell pain crisis or acute chest syndrome. It aims to ease pain and possibly lower side effects from opioids.
BordeauxAges 18 years+ - NCT07270276Recruiting
Dry needling for shoulder muscle pain
This study tests if dry needling (a therapy that uses thin needles to release muscle knots) can help with shoulder muscle pain. It uses special tests to measure how the treatment affects your muscles and pain.
Boston, MassachusettsAges 18–80 - NCT07271849RecruitingPhase 4
Timing of Nalbuphine for Pain and Blood Pressure in Older Knee Surgery Patients
This study tests whether giving the pain medicine nalbuphine at different times during knee replacement surgery affects blood pressure and pain control in older adults. It may help find the best timing to reduce pain and keep vital signs stable.
Jinan, ShandongAges 65–90 - NCT07278050Recruiting
Comparing two nerve blocks for shoulder surgery
This trial compares two types of nerve blocks (interscalene and serratus posterior superior intercostal plane block) for pain relief during shoulder surgery. If you are having arthroscopic shoulder surgery under general anesthesia, you may be able to join.
Istanbul, BagcilarAges 18–75 - NCT06545409Recruiting
Nerve block for pain relief in robotic thymus surgery
This trial tests a nerve block to reduce pain after robotic thymus surgery. It may help patients with thymus growths or cysts have less pain and use fewer painkillers after their operation.
RomeAges 18 years+ - NCT06819033RecruitingPhase 4
Light therapy for canker sores in children
This study tests whether a special light treatment (photobiomodulation) can help reduce pain from canker sores (aphthous ulcers) in children. It may be a good option for kids who get painful mouth sores during dental visits.
Houston, TexasAges 5–17 - NCT05050409Recruiting
Program to help recovery after knee replacement surgery
This trial tests a supportive, coach-like “embedded” program designed to help you stay engaged and ready for recovery after one knee replacement. It may be helpful if you want extra support before and after surgery to follow through with your recovery plan.
Fort Sam Houston, TexasAges 18 years+ - NCT05761275Recruiting
Sexual quality of life after minimally invasive benign surgery
This study looks at how minimally invasive “vNOTES” surgery affects women’s sexual quality of life after a non-cancer (benign) gynecologic procedure. You might be eligible if you recently had this type of surgery and meet specific health, infection, and language requirements.
GenevaAges 18–70 - NCT07268118RecruitingPhase 2
Pain relief for cervical ripening balloon in labor
This study tests if using lidocaine gel on the cervix before placing a ripening balloon can reduce pain for pregnant women at full term. It may help women who want this balloon to start labor feel more comfortable.
Boston, MassachusettsAges 18 years+ - NCT07269106RecruitingPhase 4
Testing anrikefon for pain relief after eye surgery
This trial tests a new painkiller called anrikefon for people having eye surgery under general anesthesia. It aims to see if it's safe and effective for controlling pain after the procedure.
Guangzhou, GuangdongAges 18–70 - NCT07266987Recruiting
Multisensory methods for comfort during thyroid biopsy
This study tests whether adding multisensory methods (like calming sounds or visuals) during a thyroid biopsy can make the procedure more comfortable for patients. It involves watching a short video before the biopsy and answering questions about your comfort level.
Muş, CenterAges 18–90 - NCT07267052Recruiting
Nerve stimulation at acupoints for pain relief
This trial uses a gentle electrical device on acupuncture points to study how it affects pain signals in the body. Healthy adults can join to help researchers understand a possible drug-free way to manage pain.
Taichung, Beitun, TaiwanAges 20 years+ - NCT07264699Recruiting
Guided nerve block for hernia repair pain control
This trial tests whether a visually guided nerve block (TAP block) during laparoscopic hernia repair reduces pain and improves recovery. If you are having planned hernia surgery, this study may help you experience less pain after the procedure.
Olsztyn, Warmisko-mazurskieAges 18–80 - NCT05786599RecruitingPhase 2/Phase 3
Low-dose methadone for chemotherapy nerve pain
This trial studies whether methadone can reduce painful nerve damage caused by certain chemotherapy drugs. It is for adults who have ongoing nerve pain for months after chemotherapy ended and may help by lowering neuropathic (nerve) pain.
Nanaimo, British ColumbiaAges 19 years+ - NCT06754982Recruiting
Timing of pain, stiffness, and function in plantar fasciitis after muscle release
This trial tests whether a hands-on therapy called myofascial release can help with morning pain, stiffness, and walking in people with plantar fasciitis. It aims to see how these symptoms change over time after treatment.
Talca, Maule RegionAges 18–60 - NCT06899841RecruitingPhase 2/Phase 3
Dexmedetomidine in a nerve block for kidney stone surgery
This study tests whether adding a medicine called dexmedetomidine to a nerve block (an injection near the spine) can improve pain relief after kidney stone surgery. It is for people who are generally healthy and scheduled for a kidney stone procedure.
Asyut, Assiut GovernorateAges 18–70 - NCT07257770Recruiting
Gel for breast pain after surgery
This trial tests a soothing gel you apply to your breast to see if it relieves pain after surgery. It might help if you still feel discomfort around your surgical wound.
RomaAges 18–70 - NCT07256626Enrolling by invitation
Soundwave Wellness Study for Back Pain
This trial tests a soundwave-based wellness program for back pain. It's a simple study that asks you to follow instructions, so if you're interested in trying a non-invasive approach, this could be a good fit.
New York, New YorkAges Any age - NCT06843174RecruitingPhase 4
Methadone for pain during and after spine surgery
This trial tests if giving a single dose of methadone right before and during spine surgery can help manage pain better. If it works, you might need fewer other pain medicines after surgery.
Toronto, OntarioAges 18–65
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,138 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.