Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06358040Recruiting
Opioid dispenser after back surgery trial
This trial tests a special device that gives you pain medication (opioids) after back surgery, instead of a prescription. It may help you use just the right amount of pain medicine, and you'll use your smartphone for follow-up visits.
New York, New YorkAges 18 years+ - NCT06361108RecruitingPhase 1
Spray study for diabetic nerve pain in feet
This study tests a new spray medication (YJ001) applied to the feet to see if it is safe and helps reduce pain in people with diabetic peripheral neuropathy. You may qualify if you have diabetes, stable blood sugar, and moderate to severe nerve pain in your feet.
Fredericksburg, TexasAges 18–80 - NCT06366269Recruiting
Acupuncture first for bladder pain syndrome
This trial tests whether acupuncture can help relieve pain and pressure from bladder pain syndrome (also called interstitial cystitis). Researchers want to see if using acupuncture early can improve symptoms better than usual care.
Cleveland, OhioAges 18–89 - NCT06367777Recruiting
Neck and back nerve stimulation for pain processing
This trial studies how electrical stimulation of nerves in the neck and upper back affects the way your body processes pain. It aims to help understand pain better, which could lead to new treatments.
BrusselsAges 18–40 - NCT06368492Recruiting
Psilocybin for fibromyalgia pain
This trial tests whether psilocybin, a substance found in certain mushrooms, can help reduce pain in people with fibromyalgia. You would receive the drug and be monitored closely to see if it improves your pain levels.
Maastricht, LimburgAges 18–65 - NCT06368947Recruiting
Therapeutic play for pain and emotion in children with leukemia
This study uses therapeutic play to help children with leukemia who are getting chemotherapy better manage pain and emotions. It aims to see if playing helps them feel more in control and less distressed during treatment.
Erzurum, ErzurumAges 10–18 - NCT06374537Recruiting
Exercise program for weak kidney patients
This study tests whether a targeted exercise program can help people who are very weak due to kidney disease. If you are on dialysis, have advanced kidney disease, or have had a kidney transplant, this program may improve your strength and daily function.
Chicago, IllinoisAges 18 years+ - NCT06379997Recruiting
Oral supplement vs. shoulder injection for rotator cuff pain
This trial compares taking an oral supplement versus getting hyaluronic acid injections for ongoing shoulder pain due to a partial rotator cuff tear. It aims to see which treatment works better for improving movement and reducing pain without surgery.
Roma, RMAges 30–80 - NCT06381791RecruitingPhase 1/Phase 2
CBD for pain after shoulder surgery
This study tests if CBD (a cannabis extract) can help manage pain after rotator cuff repair surgery. It aims to find a better way to control pain and reduce the need for stronger painkillers.
Houston, TexasAges 18 years+ - NCT06384430Recruiting
Shoulder impingement tests and ultrasound in diagnosis
This study looks at how certain shoulder tests and ultrasound images relate to each other in people with shoulder impingement (a common cause of shoulder pain). It aims to improve diagnosis and understand which tests work best.
MuğlaAges 18–70 - NCT06384456RecruitingPhase 4
TXA vs Placebo for Pain After Wrist Surgery
This study tests if tranexamic acid (TXA), a medicine used to reduce bleeding, can help lessen pain right after wrist fracture surgery. You may be able to join if you had breast cancer and radiation at least a year ago, are not currently on active cancer treatment, and don't take blood thinners or daily strong pain pills.
Toronto, OntarioAges 18 years+ - NCT06385977Recruiting
Risk Factors for Chronic Prostatitis in Northwest China
This study looks for risk factors in men from Northwest China with long-term pelvic or perineal pain (chronic prostatitis) compared to healthy volunteers.
Xi'an, ShaanxiAges 18 years+ - NCT06387329RecruitingPhase 4
Antibiotic to prevent UTI after bladder Botox
This study tests whether taking a low-dose antibiotic (nitrofurantoin) before a Botox bladder injection can help prevent urinary tract infections. You may be able to join if you are getting Botox for overactive bladder or painful bladder syndrome and do not have frequent UTIs or other health issues that would make the antibiotic unsafe.
Bethesda, MarylandAges 18 years+ - NCT06393855Recruiting
Bandage contact lens shape and comfort after PRK surgery
This study tests whether different shapes of bandage contact lenses placed after PRK laser eye surgery affect pain and vision recovery. It may help people with moderate nearsightedness recover more comfortably.
Dongyang, ZhejiangAges 18–40 - NCT06393608RecruitingPhase 2
Epsom salt compresses for postpartum perineal relief
This study tests whether warm compresses with Epsom salt can soothe pain and swelling in the vaginal area after childbirth. It's for mothers who had a vaginal delivery and are staying in one of the three participating hospitals.
Chicoutimi, QuebecAges 18 years+ - NCT06393959Recruiting
Injection treatment for lumbar spinal stenosis pain
This study tests whether an injection treatment can help relieve back and leg pain caused by a narrowed spinal canal in the lower back. It is for people whose pain has lasted at least 3 months and who have not had back surgery.
Ankara, TürkiyeAges 18–90 - NCT06398574Recruiting
Dry needling for shoulder muscle function
This study tests if dry needling (using thin needles on trigger points) can change how the shoulder muscles work. It aims to help people with long-term shoulder pain or healthy people understand muscle responses.
Alcalá de Henares, MadridAges 18–70 - NCT06405776Recruiting
Lidocaine for pain and survival after bowel surgery in older adults
This study tests whether a drug called lidocaine, given during surgery, can help control pain after colon or rectal surgery and possibly improve long-term survival in older adults. The goal is to see if lidocaine offers better pain relief and recovery compared to standard care.
SichuanAges 60 years+ - NCT06406244Recruiting
TEAS for chronic pain after liver surgery
This trial tests whether a gentle, needle-free electrical stimulation on certain points on the body (called TEAS) can help reduce chronic pain after liver surgery and improve long-term survival. It may be a good option if you are scheduled for a liver removal and want to explore non-drug pain relief.
ChengduAges 18–80 - NCT06406647Recruiting
Nerve block for arm surgery
This trial tests a nerve block to help with pain during and after upper arm surgery. The goal is to see if it works well and is safe for patients.
AsyutAges 20–65 - NCT06406712Recruiting
Nerve block for arm vascular surgery
This trial tests a nerve block to numb the arm during vascular surgery. It may help manage pain and reduce the need for general anesthesia.
AsyutAges 20–65 - NCT06411054Recruiting
Acupuncture with electrical stimulation for pain during miscarriage procedure
This study tests whether adding a type of acupuncture (Acu-TENS) to standard care can reduce pain during a procedure to remove pregnancy tissue after a first-trimester miscarriage. If you are eligible, you may receive either acupuncture with a mild electrical current or a placebo device during the procedure.
Hong KongAges 18 years+ - NCT06411795RecruitingPhase 2
Comparing two pain relief methods after Whipple surgery
This study compares two ways to manage pain after Whipple surgery: a long-lasting numbing injection near the belly muscles (rectus sheath block) versus an epidural (a tube placed in your back). The goal is to see which method provides better pain relief and recovery.
Minneapolis, MinnesotaAges 18 years+ - NCT06414083Recruiting
Comparing ablation methods for endometriosis surgery
This study compares two different ablation techniques used during surgery to remove endometriosis lesions. It aims to see which method works better for relieving pelvic pain symptoms.
Cincinnati, OhioAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.