Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06479161RecruitingPhase 2
Oral tranexamic acid study for knee replacement patients
This trial tests if taking tranexamic acid (TXA) as a pill can reduce bleeding after total knee replacement surgery. It may help you if you have knee osteoarthritis and are scheduled for a first-time knee replacement.
Hartford, ConnecticutAges 18–89 - NCT06479577Recruiting
Comparing ultrasound and laser therapy for diabetic foot pain
This study compares two physical therapy methods (ultrasound and high-intensity laser therapy) to see which one better reduces nerve pain, improves strength, and boosts quality of life in people with diabetic foot pain.
Bahawalpur, Punjab ProvinceAges 50–75 - NCT06485869Recruiting
Virtual reality for better quality of life during chemo
This trial tests if using virtual reality during chemotherapy sessions can improve your quality of life. It's for people who are about to start their first round of IV chemo and have sessions lasting more than 30 minutes.
ChaunyAges 18 years+ - NCT05999721Recruiting
Nerve block for better breathing after heart surgery
This trial is testing a nerve block (a numbing injection) placed near the breastbone to see if it helps your lungs work better after heart surgery. If you are having planned heart surgery through a breastbone cut, you may be able to join.
Petah TikvaAges 18 years+ - NCT06420336Recruiting
Pain relief after cleft palate surgery
This study compares two ways to manage pain after cleft palate repair surgery that uses a bone graft from the hip. The goal is to see which method provides better pain control for children and teens.
Charleston, South CarolinaAges 6–18 - NCT07575555Recruiting
Lipedema's role in knee arthritis in women
This study compares women with knee arthritis who do or don't have lipedema (a condition causing painful fat buildup, usually in the legs) to understand how lipedema affects knee joint health. Results may help doctors better treat knee arthritis in women with lipedema.
Izmir, İzmirAges 30–65 - NCT06788717Enrolling by invitation
Study on Hip Revision Stem Performance
This study is checking how well a specific hip implant (the Comprehensive Revision Stem) works in people who need hip replacement. It helps make sure the implant is safe and effective over time.
Los Angeles, CaliforniaAges 18–100 - NCT07228390RecruitingPhase 2
Testing ritlecitinib for hidradenitis suppurativa in adults
This study tests an oral medicine called ritlecitinib for moderate to severe hidradenitis suppurativa (HS) in adults who haven't responded well to antibiotics. The goal is to see if it can reduce painful red lumps and improve quality of life.
Phoenix, ArizonaAges 18–75 - NCT04214561Enrolling by invitation
Studies how sleep measures relate to teeth grinding
This study looks at sleep testing results to understand what relates to sleep bruxism, which is teeth grinding or clenching during sleep. It may help researchers better understand the causes and patterns behind this condition.
WroclawAges 18–70 - NCT06486246Recruiting
Nerve block options for ACL surgery recovery
This trial compares two types of nerve blocks for pain relief after ACL reconstruction. It aims to find which approach provides better comfort and faster recovery.
BarcelonaAges 18–50 - NCT06488183Recruiting
Pain relief study for laparoscopic weight loss surgery
This study compares two ways to manage pain after laparoscopic bariatric surgery: one method involves numbing medicine placed near the surgery site, and the other uses an ultrasound-guided injection near the back. It aims to find which option works better for recovery in people with moderate to severe obesity.
AlexandriaAges 20–50 - NCT06488547Recruiting
Stress and muscle health study for Greek workers
This trial looks at how stress affects muscle and bone health in employees. If you join, you'll answer questions and be measured with simple electronic devices. The goal is to find ways to help workers stay healthy.
Larissa, Biopolis- LarissaAges 19 years+ - NCT06489353Recruiting
Watching video or blowing pinwheel for kids during IV
This study tests whether watching a video or blowing a paper pinwheel helps children feel more comfortable during an IV or blood draw. It is for children ages 3 to 6 who are in the hospital and do not have certain health conditions.
TaichungAges 3–6 - NCT06491992Recruiting
Chitosan gel with ultrasound for neck pain from phone use
This trial tests if applying a special gel (chitosan) with ultrasound on the neck can help reduce pain in teens who use smartphones a lot. It might offer a non-drug way to ease discomfort from phone addiction.
Al Jīzah, Select StateAges 16–18 - NCT06492148Recruiting
Myofascial Release for Period Pain in Women
This study tests a gentle hands-on technique called myofascial release to see if it can reduce period pain in women who have primary dysmenorrhea (painful periods without an underlying condition). If you have moderate to severe cramps and don't use hormonal birth control, you may be able to join.
AnkaraAges 18–35 - NCT06497712Recruiting
Hypnosis for pain during emergency room stitches
This trial tests if hypnosis can reduce pain when getting stitches in the emergency room. If you have a stitchable wound and are at least 18 years old, you may be able to join.
Clermont-FerrandAges 18 years+ - NCT06501079Recruiting
Pain relief study: adding dexamethasone or magnesium to a nerve block for kidney removal
This study compares two different medications (dexamethasone and magnesium) added to a standard painkiller used in a nerve block for patients having one kidney removed. The goal is to find out which combination provides better pain relief after surgery.
CairoAges 18–65 - NCT06503510Recruiting
Interleukin-13 effects on pain and itch
This study looks at how a substance called interleukin-13 affects pain and itch sensations in healthy people. You will have small amounts of this substance applied to your skin to see how it changes your sensitivity to touch, pain, and itch.
Gistrup, AalborgAges 18–60 - NCT06506565RecruitingPhase 4
Low-dose ketamine for burn wound pain
This trial tests a low-dose ketamine infusion during burn wound dressing changes to see if it reduces pain. It might help people who are hospitalized with a thermal burn injury.
Memphis, TennesseeAges 18 years+ - NCT06507293Recruiting
Pain relief methods comparison for lung surgery
This trial tests two numbing injections to see which reduces pain medicine use during lung surgery. A special pain monitor guides the treatment. It may help you need fewer opioids during your procedure.
KocaeliAges 18–65 - NCT06507748Recruiting
Measuring pain with a finger device in NF1
This study tests a new way to measure pain and other sensations in people with NF1 using a device that clips onto a finger or toe. The device looks at how your pupil reacts to mild pulses, which may help doctors better understand your pain.
Washington D.C., District of ColumbiaAges 1–120 - NCT06511765RecruitingPhase 3
Nerve block for acute lower back pain: a pilot study
This study tests whether a single injection of a numbing medicine (ropivacaine) into the muscles of the lower back can quickly relieve sudden, severe back pain that has lasted less than a week. The goal is to see if this nerve block can help when standard pain pills aren't working.
Saint-HerblainAges 18 years+ - NCT06514365Recruiting
Comparing nerve blocks for pain after knee replacement
This trial compares two different ways of numbing the leg to provide better pain relief after total knee replacement surgery. It tests whether adding a popliteal sciatic nerve block (behind the knee) to a saphenous block (inner thigh) works better than adding an IPACK block (back of the knee).
Badalona, BarcelonaAges 18 years+ - NCT06514469Recruiting
Painkiller (sufentanil) given by paramedics for severe trauma pain
This trial tests whether paramedics can safely give a strong painkiller (sufentanil) to adults with severe pain from a recent injury. It aims to see if it works well and is safe when given in the field.
Karlovy Vary, Karlovy Vary RegionAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.