Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,138 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06934421Recruiting
A new approach for knee radiofrequency ablation
This trial tests a revised method for radiofrequency ablation to treat chronic knee pain from severe osteoarthritis (KL grade III or IV). It aims to see if the procedure can help patients who haven't gotten relief from standard treatments like physical therapy, painkillers, and steroid injections.
FaroAges 18 years+ - NCT07191067Recruiting
Study of NOVABLOC system for knee replacement pain
This trial tests a new device called the NOVABLOC system to see if it helps control pain during and after knee replacement surgery. It is for people with osteoarthritis who are having their first knee replacement on one knee.
Daphne, AlabamaAges 21 years+ - NCT07185594RecruitingPhase 2/Phase 3
Study of a new pain drug after abdominal surgery
This trial tests a new medication called HRS-2129 for managing pain after abdominal surgery. It is for adults who will have moderate to severe pain after their operation, and aims to see if the drug can help control that pain safely.
Zhengzhou, HenanAges 18 years+ - NCT06670768Recruiting
Comparing two heart imaging tests for blocked arteries
This trial compares two heart imaging tests (SPECT and coronary CTA) to see if a newer method gives a clearer picture of blood flow. If you have been referred for one of these tests, you may be able to help by also having the other test done at no extra risk.
Budapest, BudapestAges 18 years+ - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT07186751Recruiting
Pregabalin and venlafaxine for fibromyalgia pain
This trial tests a combination of two medicines (pregabalin and venlafaxine) for people with fibromyalgia whose pain is moderate to severe and has not been helped enough by non-drug treatments. The goal is to see if the combination works better and is safe.
BeijinAges 18 years+ - NCT07188779RecruitingPhase 2
Impact of a special gel on tonsillectomy recovery in children
This trial tests whether applying a special gel called RADA16 to the surgical site after tonsillectomy (removal of tonsils) can help children heal better and with less pain. It may offer a new way to improve recovery after this common surgery.
Livingston, New JerseyAges 3–17 - NCT07192146Recruiting
Patient experiences after dental emergency treatment
This study looks at how patients feel after receiving emergency dental treatment for tooth pain. It aims to understand what factors affect their recovery and satisfaction.
BangkokAges 18 years+ - NCT07185750Recruiting
Pain Catastrophizing in Parents of Children with JIA
This study looks at how parents of children with juvenile idiopathic arthritis (JIA) think about and react to pain. It aims to understand how parents' worry about pain might affect their child's experience.
Çankaya, AnkaraAges 7–18 - NCT07190625RecruitingEarly Phase 1
Fentanyl spray versus injection for pain in preterm babies
This trial compares giving fentanyl as a nasal spray versus an injection to help preterm babies during painful procedures like placing a central line, inserting a breathing tube, or a spinal tap. The goal is to see which method works better and is safer.
CairoAges Up to 4 weeks - NCT07176494Recruiting
Revision of Deep Brain Stimulator in Parkinson's Disease
This study is for people with Parkinson's disease who need to have their deep brain stimulator (a device that sends electrical pulses to control movement) replaced or adjusted. The researchers want to learn the best way to do this procedure safely.
Ankara, Yenimahalle\AnkaraAges 40–85 - NCT06642311Recruiting
Bladder filling for pain relief during hysteroscopy
This trial tests if filling the bladder with fluid can reduce pain during a minor procedure to look inside the uterus, for women whose uterus is tilted forward.
CairoAges 18–60 - NCT07176910Recruiting
Ultrasound-guided treatment for period pain
This trial tests a special ultrasound-guided technique to see if it can reduce pain during period cramps. It is for women with long-term painful periods that are not caused by other conditions.
ChangchunAges 18–25 - NCT07180979RecruitingPhase 4
Nerve blocks for pain relief after hip replacement
This trial compares three types of nerve blocks to find which provides the best pain relief after a hip replacement. It may help you have less pain and a smoother recovery.
PoznanAges 65–100 - NCT07174440Recruiting
Testing numbing medicine for spine surgery
This trial is testing a numbing medicine placed near the spine (erector spinae block) during lumbar spine fusion surgery. It aims to see if it helps control pain and may reduce the amount of anesthetic needed during the procedure.
Cleveland, OhioAges 21–75 - NCT07174609Recruiting
Scrambler therapy for chronic pancreatitis pain
This study tests a non-invasive pain treatment called scrambler therapy for people with chronic pancreatitis. It uses mild electrical signals on the skin to try to reduce long-term belly pain.
Baltimore, MarylandAges 18 years+ - NCT07181434Recruiting
Virtual reality for pain relief during leg artery repair
This trial tests whether using a virtual reality headset during a leg artery repair procedure can reduce pain. If you have peripheral artery disease and are having a minimally invasive leg artery surgery under local anesthesia with sedation, you may be able to participate.
PoitiersAges 18 years+ - NCT07183774Recruiting
Does muscle loss affect shoulder tear patterns?
This study looks at whether sarcopenia (age-related muscle loss) affects the type of rotator cuff tear you have. You'll get a shoulder MRI to check your rotator cuff and muscle measurements.
Istanbul, ÜsküdarAges 40–75 - NCT07177027Recruiting
Breathing exercises and music for first-time mothers in labor
This study tests whether combining breathing exercises with listening to music during labor can help first-time mothers feel less pain, have more positive expectations, and feel more satisfied with their birth experience. If you join, you will practice breathing techniques and listen to music while in labor.
Uşak, UşakAges 18–35 - NCT07180498Recruiting
Tea tree vs chlorhexidine mouthwash after wisdom tooth removal
This study compares a tea tree oil mouthwash and a standard chlorhexidine mouthwash to see which helps better after wisdom tooth removal. It may help you heal faster and with less discomfort.
SanliurfaAges 18–65 - NCT06951802RecruitingPhase 4
Low-dose ketamine for pain during endometriosis surgery
This study tests whether giving a low dose of ketamine during endometriosis surgery can help reduce pain. If you qualify, you'll receive ketamine or a placebo during your procedure, and the team will check your pain levels afterward.
BernAges 18 years+ - NCT07173231Recruiting
Using virtual reality for diagnostic hysteroscopy
This trial tests if using virtual reality (VR) can make diagnostic hysteroscopy, a procedure to look inside the uterus, more comfortable. It may help patients who are anxious about the procedure.
Montreal, QuebecAges 18 years+ - NCT07170007Recruiting
Physiotherapy after birth trauma for first-time mothers
This study tests a special physiotherapy program for first-time mothers who had a vaginal tear or episiotomy during childbirth. The goal is to see if it helps recovery better than standard care.
Ribeirão Preto, São PauloAges 18 years+ - NCT07173413Recruiting
Quality of phone check-ins after spine surgery
This study checks how well telephone follow-ups work for patients who had lower back surgery at a Danish hospital. It may help improve future care.
Aalborg, AalborgAges 18 years+
Hear when a new Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,138 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.