Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06566950Recruiting
Blood flow training for leg muscle health in athletes
This study tests a training method that uses light blood flow restriction to improve leg muscle structure. It is for young athletes (ages 15–35) who play high-level sports like martial arts, basketball, soccer, or futsal at least twice a week.
Denpasar, BaliAges 15–35 - NCT06568406Recruiting
Early physiotherapy after episiotomy for better recovery
This study tests whether starting physiotherapy early after a childbirth-related cut (episiotomy) can help with pain, pelvic floor function, sexual health, and overall quality of life.
BrnoAges 18–40 - NCT06568770RecruitingPhase 2/Phase 3
Comparing two nerve blocks for femur fracture surgery pain
This trial tests if one type of nerve block (PENG block) works better than another (S-FICB) for controlling pain during and after femur fracture surgery. Both blocks are guided by ultrasound to help with your recovery.
Sahiwal, Punjab ProvinceAges 20–70 - NCT06572241Recruiting
Spinal morphine for better labor pain relief
This study tests whether adding a small dose of morphine into the spinal fluid improves pain relief from an epidural during labor. If you are having your first baby and want pain relief, you may be able to take part.
Toronto, OntarioAges 18–50 - NCT06574165Recruiting
Pain, mood, and brain inflammation in veterans with fibromyalgia
This study looks at how brain inflammation and mood relate to pain in veterans with fibromyalgia. It may help find new ways to treat pain by understanding these connections.
Birmingham, AlabamaAges 19–85 - NCT06574841Recruiting
Blood flow restriction therapy for carpal tunnel syndrome
This study tests a new hand therapy that uses a special band to lightly restrict blood flow while you do exercises. It may help reduce pain, improve grip strength, and nerve function in people with carpal tunnel syndrome.
CairoAges 30–55 - NCT06575322Recruiting
Neoadjuvant therapy for head and neck cancer: effects on pain and mood
This trial tests whether adding immunotherapy to chemotherapy before surgery can help reduce pain, anxiety, and depression in people with head and neck cancer. The goal is to see if this approach improves quality of life during treatment.
Guanzhou, GuangdongAges 18–80 - NCT06576557Recruiting
Exercise and education for knee pain from meniscal tear
This study tests whether a special exercise and education program, designed by experts, can help people with knee pain from meniscal tears or early arthritis feel better and move better. It is run by a university and involves working with your GP and a physiotherapist.
Tralee, KerryAges 35–69 - NCT06576830RecruitingPhase 4
Pain relief study for kids having tonsil surgery
This study tests different ways to manage pain after tonsillectomy in children. The goal is to find better pain relief options.
Durham, North CarolinaAges 3–17 - NCT06580327Recruiting
Epidural Drip vs. Intermittent Doses for Women in Labor
This study compares two ways of giving epidural pain medicine during labor—continuous drip versus intermittent doses. It is for women who have given birth before and are in early labor with a single, head-down baby.
NazarethAges Any age - NCT06580561Recruiting
Exercise and insomnia treatment for knee pain
This study combines a gentle exercise program with a treatment for insomnia to see if it helps older adults with knee osteoarthritis feel less pain and sleep better. You will attend group exercise classes and receive sleep coaching.
Ann Arbor, MichiganAges 50 years+ - NCT06583122Recruiting
Nerve block study for occipital pain or migraine
This trial tests if using ultrasound-guided heat (radiofrequency ablation) on the occipital nerve can reduce headache pain. It is for people with occipital neuralgia or migraine pain at the back of the head who haven't had enough relief from oral medications.
Kansas City, KansasAges 18–80 - NCT06586840Recruiting
Adding an extra nerve block to knee replacement
This trial tests if adding a special nerve block behind the knee (IPACK) to a standard thigh block helps control pain better after total knee replacement. It may lead to less pain and faster recovery.
AydinAges 18–85 - NCT06587607Recruiting
VR mindfulness training for veterans with spinal cord injury
This study tests whether mindfulness training with virtual reality can help veterans with spinal cord injury manage chronic pain. It is done from home using a VR headset and group video calls.
Houston, TexasAges 18 years+ - NCT06590714Recruiting
Polmacoxib for pain after rotator cuff surgery
This trial tests if Polmacoxib, an anti-inflammatory drug, can reduce the need for stronger painkillers after rotator cuff surgery. It may help manage pain with fewer side effects.
Uijeongbu-si, Gyeonggi-doAges 18 years+ - NCT06593977Recruiting
Dynavisc gel for pain after repeat carpal tunnel surgery
This trial tests a gel called Dynavisc to see if it reduces pain when placed in the wrist during a second surgery for carpal tunnel syndrome. It may help people who still have pain after their first surgery.
Leuven, BelgiumAges 18–65 - NCT06598293Recruiting
Using smartphone surveys during and after radiation therapy
This study tests if regularly answering health questions on a smartphone can help doctors better support patients during and after radiation treatment. You will use an app to report how you are feeling, and your care team may use this information to adjust your care.
Yongin-siAges 19 years+ - NCT07690449Recruiting
CT signs of nerve irritation in sciatica
This study looks at three specific signs on a CT scan that may show nerve-root irritation in people with sciatica. It only includes patients who are already scheduled for a CT-guided nerve injection to treat their pain.
Nice, Alpes MaritimesAges 18 years+ - NCT07267052Recruiting
Nerve stimulation at acupoints for pain relief
This trial uses a gentle electrical device on acupuncture points to study how it affects pain signals in the body. Healthy adults can join to help researchers understand a possible drug-free way to manage pain.
Taichung, Beitun, TaiwanAges 20 years+ - NCT06915363Recruiting
BioPoly implant for knee cartilage repair
This trial tests a BioPoly implant to repair a small damaged cartilage spot in your knee. If you have a specific type of cartilage injury that didn't get better with other treatments, this implant may help relieve pain and improve function.
Fort Wayne, IndianaAges 30–65 - NCT06915909Recruiting
Robotic prostate surgery with low pressure gas for less pain
This trial tests whether using lower gas pressure during robotic prostate surgery can reduce pain after the operation. It aims to help men recover more comfortably.
Stevenage, HertfordshireAges 18–75 - NCT07235098Recruiting
Music therapy for lung cancer surgery patients
This trial tests whether listening to music in the hospital can help reduce distress and pain after surgery for lung cancer. If you are having a minimally invasive surgery (keyhole surgery) to remove part of your lung, you may be able to join.
Bellinzona, Canton TicinoAges 18 years+ - NCT07443930Recruiting
Musicians' Health Education Study
This study looks at how well health education programs work for musicians. You can take part simply by filling out a questionnaire.
GöttingenAges Any age - NCT06600815Recruiting
Step-by-step numbing shots for pain relief in knee replacement
This study tests whether a special step-by-step numbing injection given before knee replacement surgery can provide better pain relief during and after the procedure. It may help you have less pain and use fewer painkillers after surgery.
Fuzhou, FujianAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.