Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07081048Recruiting
Reducing newborn pain during a heel stick blood test
This study tests two pain-relief methods during a heel stick blood draw in full-term newborns. The goal is to find which method helps babies feel less pain and stay more comfortable.
MersinAges 1 day–1 month - NCT07081373Recruiting
Repeat dose of liposomal bupivacaine for pain after anal fistula surgery
This trial tests if a repeat dose of liposomal bupivacaine (a long-acting numbing medicine) helps reduce pain after surgery for anal fistula. It may be a good option if you are having this surgery and want better pain control.
Guangzhou, GuangdongAges 18–60 - NCT07084935Recruiting
Comparing pain monitors during children’s surgery
This trial compares two devices that measure pain levels during surgery in children. It may help doctors better manage pain for children having planned surgery with general anesthesia.
Nijmegen, GelderlandAges 1–12 - NCT07085247Recruiting
Role of bacteria in lower back disc disease
This trial looks at whether a specific bacteria, Cutibacterium acnes, is linked to disc problems in the lower back. If you're having surgery for a herniated disc, your tissue sample may help researchers understand the cause.
BrnoAges 18 years+ - NCT07090668Recruiting
Ear stimulation for pain in sickle cell disease
This trial tests a safe, non-drug device that gently stimulates the ear to help reduce pain in children with sickle cell disease who are in the hospital for a pain crisis. It may offer a new way to manage pain without extra medication.
Atlanta, GeorgiaAges 7–18 - NCT07090928RecruitingPhase 4
Numbing medicine for less pain after knee scope surgery
This study tests whether giving bupivacaine (a numbing medicine) around the time of knee arthroscopy can reduce pain at the surgery sites and help you move your knee better after the operation.
Peshawar, KPKAges 18–70 - NCT07092566RecruitingPhase 3
Pain relief after robotic kidney surgery: R.E.C.K. vs Exparel
This trial tests two different pain-relief medicines (R.E.C.K. and Exparel) given during robotic kidney surgery. It aims to find which works better to control pain after the operation.
Charlotte, North CarolinaAges 18 years+ - NCT07093437Recruiting
Comparing ways to secure urinary catheters in ICU patients
This study compares two methods of securing a urinary catheter to the thigh to see which works better. It's for patients in the intensive care unit (ICU) who need a catheter for more than 48 hours.
BarcelonaAges 18–99 - NCT07094386Recruiting
Pain relief study after open upper abdominal surgery
This trial compares two types of nerve blocks to control pain after open upper abdominal surgery. It aims to find which block works better and may help you recover with less pain.
CairoAges 18–60 - NCT07094997Recruiting
Massage therapy for healthcare workers with low back pain
This study tests if massage therapy can help healthcare workers with ongoing low back pain. If you qualify, you would receive several massage sessions to see if they reduce your pain and improve your well-being.
Wroclaw, Lower Silesian VoivodeshipAges 30–65 - NCT07095569Recruiting
Shoulder nerve block for pain after breast cancer radiation
This trial tests a procedure to block shoulder nerves to relieve pain caused by radiation therapy after mastectomy. It may help if you have ongoing shoulder pain after breast cancer treatment.
Cairo, Cairo GovernorateAges 18–65 - NCT07095556Recruiting
Laser therapy to help gums heal after tooth extraction
This trial tests whether a special laser treatment can help your gums heal better after a tooth is removed and the socket is prepared for a future dental implant. If you're having a tooth pulled and bone preservation, this laser might speed up healing and reduce pain.
Charleston, South CarolinaAges 18 years+ - NCT07095608Recruiting
Study on nerve cells and oral cancer pain
This study looks at how certain nerve cells might be involved in oral cancer pain. It aims to find new ways to treat pain by testing tissue samples from people with oral cancer and healthy volunteers.
New York, New YorkAges 18 years+ - NCT07096349Recruiting
Chronic pain study in severe hemophilia A
This study looks at chronic pain in people with severe hemophilia A. It aims to understand pain better through questionnaires and joint health checks.
Oviedo, Principality of AsturiasAges 18 years+ - NCT07099560Recruiting
Comparing two numbing blocks for hypospadias repair in children
This study compares two ways to numb the lower belly and groin area for children having hypospadias repair. It tests if a newer injection method (sacral erector spinae block) works as well as the standard method (caudal block) to control pain during and after surgery.
Tanta, El-Gharbia GovenorateAges 1–5 - NCT07100613RecruitingPhase 2
Mouth film for treating oral lichen planus
This trial tests a new sticky mouth film that slowly releases medicine to treat painful sores from oral lichen planus. It may help people who have not been treated before for this condition.
Palermo, ItalyAges 18 years+ - NCT07101068Recruiting
Comparing two ways to give dental numbing for kids
This study tests a new dental injector against a traditional syringe to see which one causes less pain and anxiety for children getting numbed for their first cavity treatment.
Cairo, Cairo GovernorateAges 6–8 - NCT07101887Recruiting
Comparing two surgeries for thumb arthritis pain and function
This trial tests if a thumb joint replacement works better than the standard surgery for reducing pain and improving hand use in people with thumb arthritis (grades I to III).
BarcelonaAges Any age - NCT07108192Recruiting
Hand holding and stress ball for cataract surgery comfort
This study tests whether holding a stress ball or having your hand held during cataract surgery can help lower pain and anxiety. It is for people having their first cataract surgery and who are not on certain medications.
SakaryaAges 18 years+ - NCT07109557Recruiting
Baduanjin for recovery after knee replacement
This study tests whether doing Baduanjin, a gentle mind-body exercise, helps people recover better after knee replacement surgery. It focuses on patients who are in stable condition and willing to try the exercise.
YalovaAges 18–70 - NCT07112690Recruiting
Nerve block for radiation pain during anal cancer treatment
This study tests a nerve block procedure (ganglion impar neurolysis) to reduce severe pain caused by radiation therapy for anal or perianal skin cancer. It may help you manage pain while you continue your cancer treatment.
Atlanta, GeorgiaAges 18 years+ - NCT07113080RecruitingPhase 4
Do Lemongrass and Lavender Help Kids With Dental Shots?
This study tests whether smelling lemongrass and lavender scents can help reduce fear and pain when a child gets a numbing shot at the dentist. It is for children ages 7 to 11 who are healthy and have never been to the dentist before.
Cairo, Cairo GovernorateAges 7–11 - NCT07113483RecruitingPhase 3
Remimazolam vs. Midazolam for sedation in older adults having orthopedic surgery
This trial compares two sedatives, remimazolam and midazolam, to see which one leads to better recovery of thinking skills after orthopedic surgery. It is for people aged 65 and older who are having surgery on a bone or joint while awake but relaxed.
BucharestAges 65 years+ - NCT07114003Recruiting
Virtual reality for pain and anxiety during wound dressing changes
This study tests whether using virtual reality during wound dressing changes can help reduce pain and anxiety and improve satisfaction for people with pressure sores (bedsores).
Mersin, TarsusAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.