Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,136 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06358040Recruiting
Opioid dispenser after back surgery trial
This trial tests a special device that gives you pain medication (opioids) after back surgery, instead of a prescription. It may help you use just the right amount of pain medicine, and you'll use your smartphone for follow-up visits.
New York, New YorkAges 18 years+ - NCT06355271Recruiting
Pain relief and recovery after planned C-section
This trial studies how well pain is controlled and how quickly women recover after a planned C-section under spinal anesthesia. It compares different pain relief methods to find the best approach.
BellinzonaAges 18 years+ - NCT06346132Recruiting
Does virtual reality help during heart device surgery?
This study tests if wearing a virtual reality headset during a heart device implant or battery change helps you feel more comfortable and relaxed. The surgery is done under local anesthesia (numbing medicine) while you stay awake, and you go home the same day.
Lugano, Canton TicinoAges 18 years+ - NCT05067998Recruiting
Natural medicine and vitamin IV study for overall health
This study looks at whether natural medicine, vitamin IV fluids, and supplements can help people maintain good health. There don’t appear to be specific eligibility limits listed, so many people may be able to join, but you’d still need screening by the study team.
Dover, DelawareAges 21–80 - NCT06330779Recruiting
Trauma-adapted yoga for teens with PTSD or ADHD
This trial tests if a special yoga program helps teenagers with PTSD or ADHD feel better. It is designed to be safe and supportive for their mental health.
GothenburgAges 12–18 - NCT06337513Enrolling by invitation
Back pain study for early arthritis diagnosis
This trial looks at people with low back pain to find early signs of a spine arthritis condition. It may help diagnose the condition sooner and guide better treatment.
Sønderborg, Southern DenmarkAges 18–48 - NCT06328062Recruiting
Comparing two pain medicines for knee replacement
This study compares two medicines, mirogabalin and pregabalin, to see which works better for pain after total knee replacement. It may help you find more effective pain relief after surgery.
Khlong Luang, Changwat Pathum ThaniAges 50–85 - NCT06324942Recruiting
Nerve block for C-section pain relief
This study tests whether an extra nerve block (called a TAP block) given by your surgeon during a planned C-section can provide better pain relief than standard care alone. Researchers want to see if it reduces the need for stronger pain medicines after delivery.
Calgary, AlbertaAges 18 years+ - NCT06030570Recruiting
Spine rehab program: how well does it work?
This trial tests a spine rehabilitation program that combines different types of care (like physical therapy and counseling) for adults with spine problems that haven't gotten better on their own. It aims to see if this program helps improve function and quality of life.
LeuvenAges 18 years+ - NCT06312696Recruiting
Neck movement study with spinal manipulation therapy
This study tests whether a special hands-on therapy (spinal manipulation) can help people with long-term neck pain. It will measure how the neck moves and whether the treatment improves movement and reduces pain.
Minneapolis, MinnesotaAges 18–39 - NCT06295471Recruiting
Comparing pain and healing after two laser treatments on thighs
This study compares two types of lasers (a new DFG laser and a standard CO2 laser) to see which one causes less pain and helps your skin heal better after a fractional laser treatment on your thighs. If you're looking to improve skin texture or reduce signs of aging, this might be an option.
Boston, MassachusettsAges 18 years+ - NCT06297200Recruiting
Ultrasound treatment for complex back pain patients
This study tests a new, non-invasive ultrasound treatment for people with long-term back pain who also have opioid use disorder and anxiety. It aims to see if this gentle brain stimulation can reduce pain and improve quality of life.
Roanoke, VirginiaAges 18–65 - NCT06315179Recruiting
Spatial gene study for inflammatory bowel disease
This study looks at tissue samples from people with suspected Crohn's disease, ulcerative colitis, or indeterminate colitis. The goal is to understand these conditions better and may lead to improved treatments.
Seattle, WashingtonAges 6–21 - NCT06275191Enrolling by invitation
Testing non-opioid pain relief after tooth extraction
This trial tests whether alternative pain treatments can replace opioid painkillers after wisdom tooth or other tooth removal in teens and young adults. It aims to find safer ways to manage dental pain without relying on opioids.
Lexington, KentuckyAges 12–25 - NCT06290063RecruitingPhase 2
CBD for older adults who use cannabis
This study tests whether a pure CBD product (Epidiolex) can help older adults who use cannabis occasionally. It looks at how CBD affects people who already take medications for pain, sleep, or mood issues.
Boulder, ColoradoAges 60 years+ - NCT06276257Recruiting
Pain block for mastectomy with immediate reconstruction
This trial tests a nerve block to reduce pain after breast removal surgery with immediate reconstruction. It may help you recover with less discomfort.
Québec, QuebecAges 18–70 - NCT06283862Recruiting
Virtual cannabis coaching for veterans with chronic pain
This study tests a virtual program to help veterans with chronic pain who are using (or planning to use) CBD or cannabis. You'll join educational sessions and track your symptoms and cannabis use on your smartphone.
Ann Arbor, MichiganAges 18 years+ - NCT06284473RecruitingPhase 4
Ketamine with numbing medicine for minor emergency procedures
This study tests whether adding ketamine to the usual numbing medicine makes minor procedures in the emergency department less painful. You may be a good fit if you are having a small procedure like stitches or abscess drainage.
Maywood, IllinoisAges 7–70 - NCT06291051Recruiting
Spinal cord stimulation for Parkinson's with painful bent spine
This study tests whether a spinal cord stimulator (a device that sends mild electrical pulses to the back) is safe and can reduce pain and improve the forward-bent posture in people with Parkinson's disease. It is for those whose bent posture has not improved with standard medication and is causing significant pain.
AmiensAges 18 years+ - NCT06287515RecruitingPhase 1
Radiation to the pituitary gland for cancer pain
This study tests a focused radiation treatment on a small gland in the brain to see if it can relieve cancer-related pain that hasn't been controlled by standard treatments like painkillers or other therapies. It may help patients whose pain limits their daily life.
Houston, TexasAges 18 years+ - NCT04130269Recruiting
Study of stress, anxiety, and pain after heart attack
This study looks at how anxiety, stress, and pain may affect people after a heart attack. It may help researchers understand who could benefit from supportive strategies after myocardial infarction (heart attack).
Graz, StyriaAges 19–90 - NCT06271265RecruitingPhase 1
Testing EXPAREL for pain after heart surgery in children
This study tests a long-acting pain medicine (EXPAREL) given during heart surgery to see how it works in young children. The goal is to help control pain after surgery with fewer side effects.
Indianapolis, IndianaAges birth–6 years - NCT06248216Recruiting
Virtual reality therapy for cancer treatment side effects
This study tests whether virtual reality (VR) can help ease common cancer-treatment side effects like pain, anxiety, sleep trouble, fatigue, or numbness. You may be able to join if you finished your main cancer treatment at least 3 months ago and have one of these symptoms.
Baltimore, MarylandAges 18–88 - NCT06242821Recruiting
Yoga for back pain in teen scoliosis
This study tests whether yoga can help reduce back pain in teens with scoliosis (curved spine). You would practice yoga at home through online sessions, as an alternative to or alongside physical therapy.
Baltimore, MarylandAges 10–20
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,136 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.