Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02355457Recruiting
Blood marker study in new heart attack symptoms
This study looks at blood “biomarkers” (signals in blood tests) in people who arrive with symptoms that could be a heart attack. It may help doctors spot and manage acute heart problems sooner and more accurately.
HamburgAges 18 years+ - NCT02844738RecruitingPhase 2
Cell therapy for shoulder osteoarthritis pain and inflammation
This trial tests a treatment using your own (autologous) regenerative cells to reduce pain and inflammation from shoulder osteoarthritis. It may help people with long-lasting shoulder pain, but you must meet several health and medication timing requirements.
Grove City, PennsylvaniaAges 18–90 - NCT02844764RecruitingPhase 2
Cell therapy test for hip osteoarthritis pain and swelling
This trial tests an “autologous” regenerative cell treatment, meaning cells taken from you, to reduce hip osteoarthritis pain and inflammation. It checks safety first and looks for improvements in how you feel and move.
Grove City, PennsylvaniaAges 18–90 - NCT02844751RecruitingPhase 2
Regenerative knee cell therapy for arthritis pain and swelling
This Phase 2 study tests a patient’s own (autologous) regenerative cell treatment to reduce knee pain and inflammation from osteoarthritis. It mainly looks at whether the treatment is safe and whether it can improve symptoms over time.
Grove City, PennsylvaniaAges 18–90 - NCT02463266Recruiting
PACE/PACENET program outcomes study for people 65+
This study looks at how well the PACE/PACENET care program works for older adults over time. If you join, you’ll provide consent for a check-in about your outcomes about 3 months after the acute (most intense) phase of care ends, with follow-up around 6 months.
Philadelphia, PennsylvaniaAges 65 years+ - NCT03382938Recruiting
Dexmedetomidine injected into C-section wounds
This trial studies whether a specific numbing/comfort medicine (dexmedetomidine) injected into the wound area during a C-section can improve recovery or reduce symptoms after surgery. You may be able to take part if you are a low-risk pregnancy and meet safety requirements.
Athens, OtherAges 18–40 - NCT05851768Recruiting
Easing thoracotomy pain with two different drugs
This trial compares two drugs added to a standard numbing medicine to see which works better for pain relief after chest surgery (thoracotomy). It may help find a way to reduce pain more effectively.
CairoAges 18–65 - NCT07675473RecruitingPhase 4
Pain relief before lung nodule localization
This trial tests giving a pain medicine (parecoxib) before a CT-guided lung nodule procedure to see if it reduces pain during the treatment. It's for people with non-small cell lung cancer who need a wire placed in their lung before surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07676422Recruiting
Stress ball use during mouth care
This study tests if squeezing a stress ball during mouth care can help reduce discomfort or stress. You may be able to join if you can follow instructions and don't have any hand or movement issues.
VanAges 18 years+ - NCT07676110Recruiting
Music and nature visuals for emotional well-being
This study tests if listening to enhanced music and watching natural visuals can improve your emotional health. You'll use your own headphones and a smartphone or tablet to take part.
Fort Collins, ColoradoAges 13 years+ - NCT07037888RecruitingPhase 4
Ketorolac for pain after hip arthroscopy
This study tests whether ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), helps manage pain after hip surgery. It may offer an opioid-sparing option for patients with femoroacetabular impingement (FAI).
Detroit, MichiganAges 18–89 - NCT06799052Recruiting
Cervical preparation for same-day abortion procedure
This study compares two methods of preparing the cervix (the opening to the uterus) on the same day as a dilation and evacuation (D&E) procedure for abortion at 16 to 18 weeks of pregnancy. The goal is to see which preparation approach works best and is safest.
Boston, MassachusettsAges 16 years+ - NCT07632274RecruitingPhase 1
Testing a pain reliever liquid for children ages 6–11
This study tests a new liquid medicine that combines ibuprofen and acetaminophen (two common over-the-counter pain relievers) in children aged 6 to 11. Researchers want to see how well the medicine works and how safe it is for mild to moderate pain, such as headaches, toothaches, or pain after dental work or vaccines.
Salt Lake City, UtahAges 6–11 - NCT02911090Enrolling by invitation
Register your endometriosis or pelvic pain information
This trial is a patient registry that collects information from people seen at a specialized clinic for endometriosis and chronic pelvic pain. Sharing your questionnaire helps the team better understand symptoms and care needs over time.
Vancouver, British ColumbiaAges Any age - NCT07400640Recruiting
Comparing two treatments for postherpetic neuralgia pain
This trial compares two procedures—a nerve block injection and a radiofrequency treatment—to see which works better for lasting pain after shingles. It aims to help people with persistent pain in the neck, chest, or lower back.
AnkaraAges 18–80 - NCT07401134RecruitingPhase 4
Pain relief study after vaginal surgery using witch hazel and spray
This trial tests a pain relief routine using witch hazel pads and a numbing spray after vaginal surgery. The goal is to see if using these products together helps with recovery and reduces the need for stronger pain medicine.
Miami, FloridaAges 18 years+ - NCT07401641Recruiting
Pain control study for oral cancer surgery
This study tests two different pain medicines (dezocine or nalbuphine) combined with sufentanil to see which helps better control pain after oral cancer surgery with free flap reconstruction. It also looks at side effects and how well the transplanted tissue survives.
Guangzhou, GuangdongAges 18–70 - NCT07402577Recruiting
Pain and opioid use in young sarcoma survivors
This study looks at pain and opioid use in adolescents and young adults who have had sarcoma. It uses a smartphone app to track symptoms over 3 months to better understand cancer-related pain.
Buffalo, New YorkAges 12–70 - NCT07404956Recruiting
Comparing surgical and N95 masks for operating room nurses
This study checks how wearing a surgical mask or an N95 mask affects the air quality during surgery (called surgical smoke). It is for operating room nurses who work with surgical smoke regularly.
Bartın, BartınAges 18 years+ - NCT07405021Recruiting
Vagus nerve stimulation for diabetic nerve pain
This trial tests whether using a non-invasive device to stimulate the vagus nerve can reduce nerve pain and improve function in people with diabetic neuropathy. It may be a good option if you have burning or electric-shock-like foot pain despite standard diabetes care.
DamiettaAges 45–60 - NCT07405645Recruiting
Focused Ultrasound for Cancer Pain in the Head or Neck
This trial tests a non-invasive focused ultrasound treatment aimed at a specific brain area to reduce severe cancer-related pain in the head, neck, or upper chest. It may help if your pain hasn't responded to standard medications.
Boston, MassachusettsAges 18–85 - NCT07408414Recruiting
Pain relief after laser pilonidal sinus treatment
This trial studies which local numbing method works best to reduce pain after laser treatment for pilonidal sinus. It may help people with this condition feel more comfortable after their procedure.
PožegaAges 18 years+ - NCT07409337Recruiting
Self-acupressure for period pain and PMS
This trial tests if doing acupressure on yourself can reduce period pain and premenstrual symptoms over about six months. It might help if you have painful periods and are looking for a non-medicine option.
Niğde, MerkezAges 18–30 - NCT07409753RecruitingPhase 2
How oxytocin affects nerve signals in healthy women
This study tests how a single dose of oxytocin affects nerve signals in your arm. It helps researchers understand how oxytocin might change the way your body senses touch or pain.
LinköpingAges 18–65
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.