Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07375576Recruiting
Comparing partial nerve removal to root canal for severe tooth pain
This study compares two ways to treat severe tooth pain from advanced decay: a partial nerve removal (pulpotomy) versus a full root canal treatment. It aims to find which approach works better for saving the tooth.
Hatay, AntakyaAges 18–45 - NCT07377305Recruiting
Brain stimulation for nerve pain in NMOSD
This trial tests a new, non-invasive brain stimulation method (tTIS) to treat chronic nerve pain in people with neuromyelitis optica spectrum disorder (NMOSD). It aims to see if this treatment is safe and can reduce pain without surgery or drugs.
Xi'an, ShaanxiAges 18–75 - NCT07377357Recruiting
Electrical stimulation for chronic back-related leg pain
This trial tests if a single session of electrical stimulation to the sciatic nerve can quickly reduce leg pain related to low back problems. It may help if you have had chronic sciatica (leg pain from your back) for more than 6 months and your pain has recently been interfering with daily life.
Madrid, MadridAges 18–70 - NCT07378046Recruiting
Baclofen for shingles pain: a safety and effectiveness study
This study tests whether the muscle relaxant baclofen can safely reduce shingles pain. It is for adults with moderate to severe pain who have not tried this drug before.
BeijingAges 18 years+ - NCT07378059Recruiting
Loxoprofen patch for shingles pain
This trial tests if a loxoprofen skin patch (a non-steroidal anti-inflammatory drug) can safely relieve moderate to severe pain from shingles. It may be an option for people who have had shingles rash for less than 90 days.
BeijingAges 18 years+ - NCT07378865RecruitingPhase 1
How suzetrigine passes into breast milk
This study looks at how much of the study drug, suzetrigine, gets into breast milk. It helps us understand if it's safe for breastfeeding mothers and their infants.
Salt Lake City, UtahAges 18 years+ - NCT07378995Recruiting
Can play before a shot help children?
This study tests whether a fun, play-based activity given just before an antibiotic shot helps children feel less pain and fear. If your child is 4–6 years old and needs this specific shot, they may be eligible.
ErzurumAges 4–6 - NCT07384013Recruiting
Metamizole & blood thinners in cancer patients
This study is checking if metamizole (a common painkiller) changes how well the blood thinners apixaban or rivaroxaban work in cancer patients. It aims to help doctors safely use both medicines together for pain and blood clot prevention.
HaifaAges 18 years+ - NCT07385677Recruiting
Comparing a new approach to usual care for lateral elbow pain
This trial tests if a new way of thinking about the nerves and layers in your arm (called TINLL) works better than usual therapy for people with pain on the outside of their elbow. It may help you get better faster.
South Burlington, VermontAges 18 years+ - NCT07388953Recruiting
Nerve block for better pain relief after colon surgery
This study tests adding a special nerve block (peripheral autonomic block) to a standard abdominal wall block to see if it provides better pain relief after minimally invasive left-sided colon surgery. It may help patients experience less pain and use fewer pain medications.
Belo Horizonte, Minas GeraisAges 18–80 - NCT07390279Recruiting
Radiofrequency treatment for shingles-related nerve pain
This study tests a safe, non-surgical treatment called transcutaneous pulsed radiofrequency to see if it can help reduce nerve pain that continues after shingles. It targets the painful area through pads on the skin.
Istanbul, IstanbulAges 18 years+ - NCT07390396Recruiting
Shock wave therapy plus exercises for shoulder pain
This trial tests whether adding shock wave therapy to standard exercises helps people with chronic rotator cuff tendon pain. If you have had shoulder pain for over 3 months due to a confirmed tendon problem, this might be an option for you.
Minya, Menia GovernorateAges 30–55 - NCT07390825Recruiting
Water therapy for daily living and movement in Parkinson's
This study tests if aquatic therapy (exercises in water) can improve walking, balance, posture, pain, and daily activities for people with Parkinson's. It aims to see if water-based exercise helps more than standard care.
Çankaya, AnkaraAges 40–80 - NCT07390851Recruiting
Magnesium with lidocaine for jaw and neck muscle trigger points
This trial tests whether adding magnesium to lidocaine makes trigger point injections more effective for jaw, face, or upper shoulder pain. The results will be measured by pain scales and muscle activity tests.
Giza, Giza GovernorateAges 18–70 - NCT07391306RecruitingPhase 2/Phase 3
New treatment for interstitial cystitis without Hunner's lesions
This trial is testing a new treatment for people with painful bladder syndrome (interstitial cystitis) who do not have Hunner's lesions in their bladder. It aims to see if the treatment can help reduce pelvic pain and frequent urination.
MoscowAges 18–65 - NCT07393958Recruiting
Can food supplements improve quality of life with endometriosis pain?
This study tests if a food supplement (Doliral®) can help reduce pelvic pain and improve daily life in women with endometriosis. It is for those with mild to moderate endometriosis (stages I–III) who have had pain for at least three months but do not need surgery right now.
BarcelonaAges 18 years+ - NCT07396246RecruitingPhase 2
Comparing two treatments for hip pain
This trial tests if a new artery-blocking procedure works better than platelet-rich plasma shots for people with chronic hip pain (greater trochanteric pain syndrome) who haven't improved with physical therapy or anti-inflammatory drugs.
GuimarãesAges 18–80 - NCT00389142Recruiting
Find genes linked to bladder pain and urinary symptoms
This study looks for genetic (inherited) causes of bladder pain syndrome (IC/BPS), using information from people who have typical urinary symptoms. It may help doctors understand why IC/BPS happens, which could guide better future care.
Boston, MassachusettsAges 1 year+ - NCT00823563Recruiting
Testing heart artery causes of pain without major blockage
This study looks at people who are being checked for possible heart artery–related chest or similar discomfort, but without major artery blockage (non-obstructive arteries). It aims to help doctors understand what might be causing symptoms and guide safer testing.
Stanford, CaliforniaAges 18 years+ - NCT00081523Recruiting
Understanding How Sickle Cell Disease Develops Over Time
This research study follows people with sickle cell disease to learn how the condition affects their health over many years. By studying patients regularly, researchers hope to better understand the disease and improve care.
Washington D.C., District of ColumbiaAges 2–90 - NCT00051857Recruiting
MRI Study of Muscle and Bone Function
This research study uses MRI scans (a safe imaging tool) to understand how bones, muscles, and joints work. Researchers are looking for both people with muscle or bone injuries and healthy volunteers to compare how the body moves and functions.
Bethesda, MarylandAges 5–95 - NCT01788410Recruiting
MRI-guided freezing treatment for neck, head, and spine pain
This trial studies an MRI-guided procedure that “freezes” targeted nerves or joints to reduce pain in the head, neck, or spine. It may help if your pain comes from a joint problem or a compressed/damaged nerve and you can safely have MRI scans before and after the treatment.
Boston, MassachusettsAges 18 years+ - NCT01550575Recruiting
Study of outcomes in people treated with Boston Scientific devices
This study looks back at what happened to patients after treatment (or if they could have used) Boston Scientific medical devices. It may help improve how these devices are used and understand real-world results.
Lake Havasu City, ArizonaAges 18 years+ - NCT02329093Recruiting
Hip osteoarthritis with pain, testing non-weight bearing
This study looks at whether reducing weight on the hip can help slow how hip arthritis shows up on X-rays in people who have hip joint pain. It may be an option if your pain is from hip arthritis rather than a clear fracture.
Matsumoto, NaganoAges Any age
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.