Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,262 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07264270RecruitingPhase 1
A new injection for long-term sciatica pain
This trial tests a new medicine called C-1101, given as a shot into the spine, to see if it safely reduces pain from chronic sciatica. It is for people who have not gotten enough relief from standard treatments.
Broadmeadow, New South WalesAges 18–65 - NCT07281651Recruiting
Understanding pain sensitivity in knee pain and fibromyalgia
This study looks at how the brain and nerves process pain in people with knee pain or fibromyalgia. It compares them to pain-free people to understand differences in muscle signals.
Derby, DerbyshireAges 40 years+ - NCT07288047Recruiting
Virtual reality for pain during early abortion
This study tests if using a virtual reality headset during a first trimester procedural abortion can help reduce pain and anxiety. You may be eligible if you are planning to have an abortion at Planned Parenthood of Western Pennsylvania and meet the criteria below.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07308730Recruiting
Pain diary after gallbladder surgery
This study looks at whether using a pain diary can help people manage pain better after gallbladder removal surgery. If you are having this surgery for the first time and can read and write in Turkish, you may be able to join.
Muğla, MenteşeAges 18 years+ - NCT07308873Recruiting
Gait and knee osteoarthritis pain study
This study looks at how walking patterns relate to knee pain from osteoarthritis. It aims to understand individual differences to improve future treatments.
Pittsburgh, PennsylvaniaAges 45–80 - NCT07328126Recruiting
Muscle energy technique for low back pain relief
This trial tests a gentle muscle stretching method (muscle energy technique) on the latissimus dorsi muscle to see if it reduces pain, improves daily function, and increases spine movement in people with long-term low back pain.
Rawalpindi, Punjab ProvinceAges 30–55 - NCT07332377Recruiting
mHealth pain self-management for cancer survivors
This study tests a mobile health (smartphone) program that helps you manage pain after cancer treatment. It’s for people who have finished treatment and are in remission but still have cancer- or treatment-related pain.
Richmond, VirginiaAges 18 years+ - NCT07332845Recruiting
Neck and hamstring therapy for chronic pain
This trial tests a special exercise technique that combines shoulder blade and pelvis movements to see if it helps people with long-term neck pain and tight hamstrings.
Karachi, SindhAges 18–40 - NCT07342777Recruiting
Exercise for Pain Relief in Multiple Sclerosis
This study tests whether exercise can help reduce pain in people with multiple sclerosis. If you have MS and moderate to severe pain, you may be asked to participate in a supervised exercise program.
Aarhus, DenmarkAges 18 years+ - NCT07677969Recruiting
Arm loss, balance, pain, and daily life study
This study looks at how the percentage of arm loss affects balance, neck and back pain, daily activities, and reaction time in people with one arm amputated who use a myoelectric or bionic hand. It may help understand how to improve care and rehabilitation.
AnkaraAges 18–65 - NCT07351851Recruiting
Exercise for back pain and urine leakage in women
This study tests whether a special exercise program called PEMM (which combines pelvic floor and core exercises) can help women with both chronic low back pain and urinary incontinence. It is designed for women who have had back pain and urine leakage for at least 3 months.
Doha, Baladiyat ad DawhahAges 18–65 - NCT07356115Recruiting
Pain patterns and pain location in muscle and sports clinics
This study looks at whether people's pain patterns—measured by a simple questionnaire called PainDETECT—are linked to where their pain is and what caused it. It may help doctors better understand and treat different types of pain.
IstanbulAges 18 years+ - NCT07365566Recruiting
Pain and sleep behavior disorder study
This study looks at pain in people with a sleep condition called idiopathic REM sleep behavior disorder (iRBD), where people act out their dreams. It also includes a group of people with narcolepsy who have similar sleep issues. The goal is to understand how pain relates to these conditions.
ToulouseAges 18 years+ - NCT07368920Recruiting
TENS for low back pain in adults
This study tests if a non-invasive device called TENS (which uses gentle electrical pulses) can help relieve low back pain that comes from muscle knots or tight bands. The device is applied to the skin over the painful area.
Xi'an, ShaanxiAges 18–65 - NCT07369024RecruitingPhase 2
Study of low-dose ketamine for sickle cell pain crisis
This study tests whether a low-dose of ketamine (a pain medicine) can help children and young adults with sickle cell disease who are in a pain crisis. It aims to provide better pain relief while avoiding some side effects of standard painkillers.
Torrance, CaliforniaAges 5–20 - NCT07380789Recruiting
Managing acute chest pain after battle injuries
This study is testing better ways to manage severe chest pain after combat injuries in Ukraine. If you have chest pain from battle and are 18 or older, it may help find a treatment that works for you.
RivneAges 18–60 - NCT07392333Recruiting
Nerve ablation for chronic low back pain
This study tests a treatment that uses radiofrequency energy to target specific nerves in the spine that may be causing your low back pain. If you qualify, you would receive the OptaBlate BVN procedure and be followed over time to see how well it works.
Fort Lauderdale, FloridaAges 22 years+ - NCT07393139Recruiting
Pain after arm or leg amputation
This study looks at pain in the days right after a limb amputation surgery. It aims to better understand and manage early pain, which could help improve recovery.
BolognaAges 18 years+ - NCT07393295Recruiting
TENS for endometriosis-related pain
This trial tests whether a device called TENS can help reduce chronic pelvic pain in people with endometriosis or adenomyosis. It is designed for those who are on stable hormone therapy and willing to limit other pain medications during the study.
BordeauxAges 18 years+ - NCT00499317Recruiting
Genetic study of chronic pelvic pain and bladder symptoms
This study looks for genetic (inherited) factors behind chronic pelvic pain and related urinary and sexual symptoms. You may be able to help researchers by providing a few samples and answering short questions, which could improve understanding of these conditions.
Boston, MassachusettsAges Any age - NCT02083835Recruiting
Study to improve pain after surgery using patient questionnaires
This trial studies how to better understand and improve pain after surgery by asking patients to complete short questionnaires. It may help hospitals find ways to reduce postoperative pain and better track recovery.
JenaAges 4 years+ - NCT02890485Recruiting
Dry needling for knee pain with stair or squat pain
This study tests whether dry needling can reduce ongoing knee pain in people who feel pain around the kneecap when going up or down stairs, squatting, or running. You may be able to join if your knee pain has lasted at least 3 months and you’re referred to physical therapy.
Columbus, OhioAges 18–40 - NCT02707029Recruiting
Study of how people report pain and painful conditions
This study looks at how accurately people can describe their pain and related symptoms. It may help researchers improve how pain is measured in future studies.
Bethesda, MarylandAges 12–120 - NCT02446262Recruiting
Study of how the brain and mind shape pain in healthy adults
This study tests how people sense heat and pain, and how the brain and emotions may influence that experience. It is designed for healthy adults and may involve training sessions and (for some parts) MRI scanning.
Bethesda, MarylandAges 18–50
Hear when a new Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,262 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.