Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07150143Recruiting
Massage and exercises for chronic neck pain
This trial tests whether adding a special type of massage (connective tissue massage) and other physical therapies to standard neck stabilization exercises helps people with long-term neck pain feel better.
Ataşehir, IstanbulAges 18–65 - NCT07709416Recruiting
Testing toludesvenlafaxine for long-lasting low back pain
This study tests an experimental medication called toludesvenlafaxine to see if it can help people with long-lasting low back pain that has no clear cause. If you have moderate to severe lower back pain for more than 3 months and haven't taken antidepressants before, this may be an option for you to explore.
BeijingAges 18–75 - NCT07375914Recruiting
New approach for managing acute low back pain in the ER
This trial tests a comprehensive program that looks at your physical, mental, and social needs to treat sudden low back pain in the emergency room. It may help you get better care and avoid long-term pain.
ParisAges 18–55 - NCT05963451Recruiting
Testing treatments for long-term low back pain from facet joints
This study focuses on people with long-lasting low back pain that likely comes from the small “facet” joints in the lower spine. It aims to better understand brain, psychological, and biology changes to help optimize treatment for this type of back pain.
Sherbrooke, QuebecAges 18–75 - NCT06602349Recruiting
Lidocaine injection for chronic anal/perineal pain
This trial tests whether injecting a numbing medicine (lidocaine) into the painful area helps people with chronic, unexplained pain in the anal or perineal region. It is for patients who have not gotten relief from standard treatments and whose MRI shows no other cause.
Paris, Île-de-France RegionAges 18 years+ - NCT06995287RecruitingPhase 3
Botulinum toxin injection for severe period pain
This trial tests whether injecting botulinum toxin into the uterine muscle during a hysteroscopy can reduce severe period pain or chronic pelvic pain that hasn't improved with standard treatments. It may be an option for women who have tried hormonal therapy and pain relievers without success.
Aix-en-ProvenceAges 18 years+ - NCT05968313Recruiting
Brain scan study of pain feelings in teens who self-harm
This study uses brain activity during a task to understand how teens who self-harm react to pain and empathy. It may help researchers learn what brain differences are linked with non-suicidal self-injury and guide better support for teens.
Chengdu, SichuanAges 15–18 - NCT06600685Enrolling by invitation
Music therapy for long-term pain
This study tests whether a special type of music therapy (called FMT) can help reduce long-term pain in muscles and bones. If you have had pain for at least 3 months and can speak Swedish or English, this may be an option for you.
Eskilstuna, EskilstunaAges 18 years+ - NCT05970783RecruitingPhase 3
Jincaopian tablets for ongoing pelvic pain after pelvic infection
This trial tests whether Jincaopian tablets can reduce long-lasting pelvic pain that happened after pelvic inflammatory disease. You may be able to join if your pain is still moderate to severe and other causes of pelvic pain have been ruled out.
Beijing, Beijing MunicipalityAges 18–50 - NCT07295184Recruiting
Rebound pain and confusion after hip surgery
This study looks at a way to reduce confusion after hip surgery. If you are having planned hip surgery and get a nerve block for pain, researchers will check if rebound pain affects your recovery in the hospital.
Konya, KaratayAges 18–80 - NCT06568198RecruitingPhase 2
Brain stimulation study for chronic low back pain
This trial tests whether a noninvasive brain stimulation technique called tACS can help reduce chronic low back pain. Participants will have brain scans and receive the treatment over several sessions.
Charlestown, MassachusettsAges 18–60 - NCT05985148RecruitingPhase 1
Radiosurgery for chronic chest or stomach wall pain
This trial tests whether a precise, one-time radiation treatment (stereotactic radiosurgery) can relieve long-term pain in the chest or stomach wall. It may be an option for people whose pain is not well controlled with standard pain medicines.
Basking Ridge, New JerseyAges 18 years+ - NCT06556771Recruiting
Comparing two mobilization techniques for neck pain relief
This study compares two hands-on therapy methods (Gongs and Kaltenborn mobilization) to see which one works better for reducing mechanical neck pain. If you have neck pain that gets worse with movement or sitting still, this trial may help find a more effective treatment for you.
Attock City, Punjab ProvinceAges 18–65 - NCT06004882Recruiting
Nerve stimulation vs. steroid injection for chronic knee pain
This study compares two treatments for long-term knee pain: a nerve stimulation device placed near the knee versus a steroid shot into the joint. The goal is to see which works better for pain relief.
Houston, TexasAges 18 years+ - NCT02821741Recruiting
Testing ear stimulation effects on pain and mood
This study tests whether stimulating the outside of your ear changes how you feel pain and how your mood/feelings are measured. It’s mainly testing a non-drug, ear-based approach and whether it affects pain signals.
Bethesda, MarylandAges 18–50 - NCT06481072Recruiting
Digital therapy for kids with chronic stomach pain
This trial tests a digital (online) therapy program to help children with chronic stomach pain. It's designed for kids ages 8 to 14 who have been diagnosed with a functional abdominal pain disorder and can use a computer or tablet at home.
GothenburgAges 8–14 - NCT06418217Recruiting
Exercise and education for lateral hip pain
This study tests whether exercise and patient education can help people with long-term lateral hip pain (pain on the outside of the hip). If you've had hip pain for over 6 months and an MRI confirms the cause, you may be able to join.
Horsens, HorsensAges 18–75 - NCT07675304RecruitingEarly Phase 1
Mesotherapy for chronic low back pain study
This trial tests whether injecting a natural substance (collagen) into the lower back can safely reduce chronic pain. It may help people with pain that hasn't spread to the legs.
WarsawAges 18–65 - NCT07502209Recruiting
Two types of nerve treatment for chronic shoulder pain
This study compares two methods of treating chronic shoulder pain by using a needle to deliver a special type of electrical pulse to a nerve in the shoulder. The goal is to find which method provides better pain relief for people with shoulder pain from a rotator cuff problem.
AnkaraAges 40–80 - NCT05708729Recruiting
Brain stimulation for nerve pain after stroke
This study tests a type of brain “neuromodulation” to reduce central post-stroke pain (CPSP) and to understand how it works and whether it’s safe. It’s for people whose pain has not improved enough with certain standard pain medicines.
LeuvenAges 18–70 - NCT07240961Recruiting
Nerve block for pain after hip replacement
This study tests whether a nerve block injection in the back (called an erector spinae plane block) can provide better pain relief after a first-time hip replacement. It may help reduce the need for strong painkillers.
ManoubaAges 18–85 - NCT07301632RecruitingPhase 2
MDMA for severe chronic nerve pain
This trial tests if MDMA, combined with psychotherapy, can help people with severe chronic nerve pain that hasn't improved with standard treatments. You'll receive either MDMA or a placebo to see if it safely reduces pain and improves your quality of life.
Toronto, OntarioAges 18 years+ - NCT06198010Recruiting
Managing cancer pain better for survivors
This study tests a new way to help cancer survivors manage pain that started or got worse after their diagnosis. It's for people who rate their pain as 5 or higher on a 0-10 scale and live in rural areas or identify as Hispanic.
Scottsdale, ArizonaAges 18 years+ - NCT06562933Recruiting
Comparing electrical stimulation methods for chronic neck pain
This study compares two ways of using a type of electrical stimulation (interferential current) to treat long-term neck pain. It aims to find which method works better for people with chronic neck pain.
BoluAges 20–50
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.