Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,138 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03168802Recruiting
Ultrasound and nerve treatment for facet-joint low back pain
This study tests whether a procedure that uses focused ultrasound (MRgFUS) and/or a radiofrequency nerve treatment can reduce long-lasting low back pain caused by facet-joint arthritis. It may help people whose pain improves strongly after a targeted numbing injection to specific back nerves.
Taipei, Please SelectAges 20–79 - NCT07596953Recruiting
TECAR therapy for long-term neck pain and stiffness
This study tests whether TECAR therapy—a heat-based treatment that uses electrical energy—can reduce neck pain and improve movement in people with chronic neck stiffness. TECAR stands for capacitive and resistive energy transfer, a non-invasive technique that may help relieve pain and restore mobility.
Jeddah, Al ZahraaAges 20–40 - NCT06167330Recruiting
Titan trial: Reducing phantom limb pain
This trial tests a new method to reduce phantom limb pain (pain felt in a missing limb) using gentle electrical stimulation and simple mental exercises. It is for people with one-sided amputations who have had phantom limb pain for at least three months and still have pain episodes now.
Randwick, New South WalesAges 18 years+ - NCT06569836Recruiting
Study on digital program for chronic knee pain
This trial tests a digital program to help people manage chronic knee pain. If you are 55 or older and have had knee pain recently, this study may be a good fit.
Hong KongAges 55 years+ - NCT04936646Recruiting
Brain stimulation study for long-term nerve pain
This trial tests whether a form of brain stimulation (rTMS) can reduce chronic nerve pain that has lasted more than a year and hasn’t improved with standard treatments. It may help people whose usual pain medicines are stable but still not working well.
Grenoble, IsèreAges 18–80 - NCT07593313Recruiting
Treatment for pain after stroke using spinal stimulation
This trial tests a treatment called spinal cord stimulation for people who develop chronic pain after a stroke. The pain is caused by the stroke itself and doesn't respond well to regular pain medicines. The treatment uses a small device to send mild electrical signals to your spinal cord to reduce pain.
Nanchong, SichuanAges 18 years+ - NCT07588490Recruiting
TENS for sudden severe lower back pain in the emergency room
This trial tests a pain-relief device called TENS (a small machine that sends mild electrical pulses through your skin) for people with sudden, severe lower back pain in the emergency department. Researchers want to see if TENS can help reduce your pain quickly without extra medications.
BrusselsAges 18 years+ - NCT07593183Recruiting
Spine exercises and telehealth for postpartum lower back pain
This trial tests whether guided spine-strengthening exercises (done at home via video or in-person) can reduce lower back pain and improve posture in women recovering from childbirth. Researchers measure the curve of your lower spine and track pain relief over time.
Islamabad, Punjab ProvinceAges 20–40 - NCT07589790Recruiting
Virtual Reality and Mindfulness for Chronic Low Back Pain
This study tests whether virtual reality combined with mindfulness-based cognitive therapy can help reduce chronic low back pain lasting 3+ months. The trial aims to see if this newer approach eases pain and improves quality of life.
Suzhou, JiangsuAges 20–70 - NCT07586397Recruiting
Hip Pain Treatment Study With Physical Activity Focus
This study tests a new approach to treating long-lasting hip pain that combines psychology and exercise. It's designed for people whose hip pain is affected by worry or stress, and who aren't as physically active as they'd like to be.
Boston, MassachusettsAges 18 years+ - NCT06718374Recruiting
Chest pain differences in diabetic vs non-diabetic patients
This study compares how chest pain feels in people with and without diabetes after a heart attack. It aims to understand if diabetes changes the symptoms, which could help doctors diagnose faster.
Asyut, Asyut GovernorateAges Any age - NCT07578545Recruiting
Pain management after minimally invasive chest surgery
This study tests whether combining a specific type of chest surgery (using small cameras) with numbing injections around nerves reduces pain and the need for strong pain medications after surgery. Researchers want to see if this approach helps patients recover better with less opioid use.
Antalya, MuratpaşaAges 18–75 - NCT06715761Recruiting
Myofascial release for chronic low back pain in CrossFit athletes
This trial tests if a hands-on or tool-assisted muscle release technique can reduce long-term low back pain and improve posture in people who do CrossFit. If you have had low back pain for at least 12 weeks and do CrossFit regularly, this study may help you find relief.
Goiânia, GoiásAges 18–59 - NCT07578181Enrolling by invitation
Aromatherapy Massage for Chronic Lower Back Pain
This study tests whether massage combined with essential oils (lavender, orange, and almond oil) can help reduce chronic lower back pain that has lasted at least 6 months. Researchers want to see if aromatherapy massage is a safe and helpful treatment option.
Kırşehir, MerkezAges 18–65 - NCT07579039Recruiting
Stretching and tape for pregnancy back pain
This study tests whether combining stretching exercises with special therapeutic tape can safely reduce lower back pain during pregnancy. If it works, it could offer pregnant women a non-medication option to feel better.
Rahim Yar Khan, Punjab ProvinceAges 18–35 - NCT05605639RecruitingPhase 4
Study tests a targeted injection for neck pain
This trial studies whether an injection near the phrenic nerve can help people with neck pain. It is only for certain types of neck/diaphragm-related problems and excludes people with nerve, injury, cancer, infection, or autoimmune causes.
Dos Hermanas, SevilleAges 18–64 - NCT07571889Recruiting
Numbing spray to reduce Botox injection pain for chronic migraine
This study tests whether a numbing spray applied inside the nose before Botox injections can reduce injection pain in people with chronic migraine. The goal is to make the treatment more comfortable without affecting how well it works.
East Providence, Rhode IslandAges 18 years+ - NCT07573527Recruiting
Online therapy for upper back muscle pain from trigger points
This study tests whether remote physical therapy (done online) can help relieve neck and upper back pain caused by tight knots in your rhomboid muscles. You would receive guided exercises and treatment through video calls instead of visiting a clinic in person.
Karachi, SindhAges 18–35 - NCT07568834Recruiting
How a Podcast Helps People With Chronic Pelvic Pain
This study tests whether listening to a podcast about pelvic pain helps patients feel more informed and supported. You'll be asked to listen to audio content and share your feedback about whether it was helpful.
Nashville, TennesseeAges 18 years+ - NCT07571252RecruitingPhase 4
Pain Relief Before Jaw Surgery: A Study
This study tests whether taking pain medicine before jaw surgery (orthognathic surgery) helps reduce pain after the procedure. If you're having jaw surgery, this trial may help doctors understand the best way to manage your pain.
San JuanAges 21–65 - NCT07576244Recruiting
Core exercises and massage therapy for postpartum back pain
This study tests whether core-strengthening exercises combined with a hands-on massage technique called myofascial induction therapy can help reduce back pain after vaginal delivery. It may help you recover faster and manage pain without medication.
Sialkot, Punjab ProvinceAges 20–45 - NCT07576101Recruiting
Blood Flow Restriction Training for Lower Back Pain
This study tests whether a special exercise technique that carefully reduces blood flow to your legs while exercising can help reduce chronic lower back pain. The goal is to see if this method combined with training can strengthen your muscles and relieve pain more effectively.
IslamabadAges 18–45 - NCT06728371RecruitingPhase 3
IV methadone for pain after heart surgery
This trial tests if methadone given through a vein can control pain better after heart surgery done through a breastbone incision. It may be an option for adults having planned heart surgery who are expected to wake up and breathe on their own within 12 hours.
Hong KongAges 18 years+ - NCT06729151Recruiting
Botox vs. standard care for bladder pain and sexual health
This study compares the effect of Botox injections into the bladder versus standard care (without injections) on sexual function in women with bladder pain syndrome. It aims to see if Botox can improve both pain and sexual health.
Bethesda, MarylandAges 18–99
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,138 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.