Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07746323Recruiting
Shoulder positioning for less pain after lung surgery
This study tests whether a special arm position during lung surgery can reduce shoulder pain afterward. It may help you recover more comfortably.
Chengdu, SichuanAges 18 years+ - NCT06869967Recruiting
Pain Control After Ear Surgery (Mastoidectomy)
This study tests a pain-blocking injection to reduce pain after a specific type of ear surgery (mastoidectomy). It may help you feel less pain after your operation.
IstanbulAges 18 years+ - NCT07746973Enrolling by invitation
Magic show to reduce pain and fear during needle procedures
This study tests whether watching a magic show called 'Kuco' during a needle procedure (like getting blood drawn or an IV) helps children aged 5 to 8 feel less pain and fear. If your child needs a needle and can watch the show, they might be eligible to join.
Bingoel, BingölAges 5–8 - NCT07667556Recruiting
Frozen shoulder treatment: gentle movement, pain education, and core exercises
This study tests whether a combination of gentle joint movement techniques, pain education, and core-strengthening exercises can help people with frozen shoulder move better and feel less pain. It may be a good fit if you have been diagnosed with frozen shoulder and are looking for a drug-free treatment option.
IstanbulAges 18–65 - NCT07299006Recruiting
Study of a robot to help manage pain during IV placement in children
This trial tests whether a friendly robot named Paro can help reduce pain and anxiety in young children when they need an IV placed. If your child is between 1 and 7 years old and needs an IV, this study may help make the procedure less stressful.
BrestAges 1–7 - NCT07518953Recruiting
Can Music Help With Pain During a Nail Biopsy?
This study tests whether listening to music during a nail biopsy—a small procedure to remove a sample of nail tissue—can reduce pain and anxiety. You would listen to music during the procedure and answer a few questions about how you felt.
New York, New YorkAges 18 years+ - NCT07743606Enrolling by invitationPhase 3
Pain medicine after lower back fusion surgery
This study tests whether taking a nonsteroidal anti-inflammatory drug (NSAID) like ibuprofen after lumbar spine fusion surgery is safe and helps with pain without affecting bone healing. It may offer an alternative to stronger pain medicines.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07521280Recruiting
Custom rehab for young athletes with knee or heel pain
This trial tests personalized physical therapy exercises to help young athletes recover from Osgood-Schlatter knee pain or Sever heel pain. The study tracks how well the rehabilitation program reduces pain and helps you get back to sports.
Gdansk, Debinki 7Ages 10–17 - NCT05864053RecruitingPhase 1/Phase 2
Ketamine medicine trial for chronic nerve pain in adults
This Phase 1/2 study tests hydroxynorketamine (a related ketamine-type medicine) to see if it can reduce chronic nerve pain in the arms or legs. You may be able to join if you have nerve pain for more than 3 months and meet safety and health check requirements.
Chicago, IllinoisAges 18–75 - NCT07118332RecruitingEarly Phase 1
Psilocybin for chronic pain in veterans who smoke
This trial tests if psilocybin can help veterans with chronic pain who also smoke cigarettes. You will take psilocybin in a controlled setting to see if it reduces pain and helps with smoking.
West Haven, ConnecticutAges 21–65 - NCT07738770Recruiting
Comparing two numbing techniques for pain relief after mastectomy
This trial tests two different numbing injections to see which one works better for pain after breast cancer surgery. If you are having a mastectomy, you may be able to join and help find a better way to manage pain.
Jakarta, DKI JakartaAges 18–60 - NCT06596681RecruitingEarly Phase 1
Study of GA for hard-to-treat nerve pain
This early-phase trial tests a new treatment called GA for people with hard-to-treat neuropathic pain that hasn't improved with standard therapies. The goal is to see if it is safe and tolerable.
Beijing, Beijing MunicipalityAges 18–65 - NCT06518720RecruitingPhase 2
Psilocybin for Chronic Nerve Pain and Depression
This trial tests whether psilocybin (a psychedelic medication) can help people who have both chronic nerve pain and depression that hasn't responded to standard treatments. The goal is to see if it can reduce pain and improve mood.
Toronto, OntarioAges 18–65 - NCT07636382Recruiting
Radiation to relieve cancer-related belly pain from celiac plexus involvement
This trial tests a focused radiation treatment called stereotactic body radiotherapy (SBRT) to target pain from cancer affecting the celiac plexus—a bundle of nerves in the upper abdomen. The goal is to relieve severe, persistent pain without surgery.
Toronto, OntarioAges 18 years+ - NCT07733583Recruiting
Pelvic floor therapy and exercise for endometriosis pain
This study tests whether a special type of physical therapy (pelvic floor therapy) combined with exercise can help reduce chronic pelvic pain in women with endometriosis. It aims to see if these treatments improve pain, daily function, and quality of life.
Porto Alegre, Rio Grande do SulAges 18–45 - NCT07732764Recruiting
TENS for Pain After Chest Surgery
This trial tests if a mild electrical therapy (TENS) can reduce pain after chest surgery. It may help you need less pain medicine and feel better during recovery.
Kaohsiung City, Kaohsiung CityAges 15–85 - NCT07732556Recruiting
Nerve block comparison for shingles pain relief
This trial compares two different nerve blocks (MTP and ESP) to see which works better for treating shingles pain in the chest or back. It could help you if you have moderate to severe shingles pain that started within the last 30 days.
Tanta, El-GharbiaAges 21–60 - NCT07733752Recruiting
AI symptom-checking for spine pain in physical therapy
This trial tests if a computer tool that checks your symptoms before a visit can help you and your physical therapist make better decisions about your spine care. It is for adults with neck, mid-back, or low back pain (with or without leg pain) who are starting physical therapy.
AsyutAges 18 years+ - NCT07388368Recruiting
Root canal pain study: comparing two tooth fillings
This study compares two types of fillings used after a root canal to see which one causes less pain afterward. If you have a tooth with severe, constant pain that needs a root canal, this trial may help find the best option for you.
Rawalpindi, Punjab ProvinceAges 18–60 - NCT06984796Enrolling by invitation
Light therapy for pain during IUD insertion
This study tests if light therapy (photobiomodulation) can reduce pain when an IUD is inserted. It might help women who are anxious about pain during the procedure.
São PauloAges 18–50 - NCT07734051Enrolling by invitation
Mobilization for kneecap pain
This trial tests if adding a groin-area mobilization to foot mobilization helps with kneecap (patellofemoral) pain. It may be for you if you have one-sided kneecap pain for at least 3 months, especially when climbing stairs, squatting, or sitting for long periods.
Fāqūs, SharkeyaAges 18–40 - NCT07731295Recruiting
Pain management study for teens getting wisdom teeth removed
This study looks at how to improve pain management after wisdom tooth extraction. It focuses on teens and young adults who use cannabis regularly, to see how it affects pain and recovery.
Providence, Rhode IslandAges 15–20 - NCT07729774Recruiting
Spray-and-stretch vs. gentle pressure for back pain
This study compares two hands-on techniques—spray-and-stretch and strain-counterstrain—to see which better relieves nonspecific low back pain. It may help if you have muscle-related back pain without nerve problems or other serious conditions.
Multan, Punjab ProvinceAges 35–50 - NCT07525063Enrolling by invitation
Brain Stimulation for Fibromyalgia Pain Relief
This study tests whether a non-invasive brain stimulation technique (called TMS) can help reduce pain and improve mood in women with fibromyalgia. Researchers will use MRI scans and brain stimulation to understand how pain and reward circuits in the brain work.
Durham, North CarolinaAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.