Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06784141Recruiting
Comparing two types of cognitive behavioral therapy for chronic pain
This trial tests two different ways of doing cognitive behavioral therapy (CBT) for chronic pain — one is a standard approach, the other is tailored to your personal pain network. The goal is to see which method helps you better manage your pain and improve your quality of life.
LandauAges 18 years+ - NCT06785129Recruiting
Endometriosis and migraine study
This study looks at the link between endometriosis and migraine. Researchers want to understand how these conditions affect each other, so they need people with endometriosis, migraine, or both, as well as healthy volunteers without chronic pain.
St Louis, MissouriAges 12–45 - NCT06785350Recruiting
Smallest effective steroid dose for spine surgery pain
This study tests whether a very small amount of a steroid (betamethasone) placed around the surgical cut can help control pain after spine surgery. It aims to find the lowest dose that still works well, so patients may need fewer painkillers and recover more comfortably.
Beijing, Beijing MunicipalityAges 18–65 - NCT06785753RecruitingPhase 2
Cold therapy for tooth pain after root canal
This study tests whether applying cold (cryotherapy) to the tooth and gum can reduce pain after root canal treatment in people with severe tooth pain. It aims to find a safe, drug-free way to manage pain during the procedure.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT06795386Recruiting
Widespread pain after rapid weight loss in Black and Hispanic adults
This study looks at whether rapid weight loss from bariatric surgery leads to long-term widespread pain in Black and Hispanic adults. The goal is to understand how weight loss affects pain and find better ways to help people manage it.
New York, New YorkAges 18–75 - NCT06797973RecruitingPhase 4
Morphine for pain after planned cesarean section
This trial studies whether giving a small dose of morphine into the spinal fluid during a planned cesarean section helps with pain after surgery. It aims to find a safe and effective way to manage pain for new mothers.
AarhusAges 18 years+ - NCT06798181Recruiting
Neuropathic pain and type 2 diabetes study
This study looks at nerve pain (called neuropathic pain) in people with type 2 diabetes. It aims to understand this type of pain better so doctors can help improve comfort and quality of life.
BilecikAges 18–100 - NCT06807164RecruitingPhase 2
Comparing three injections for nerve pain after breast cancer surgery
This trial tests three different injections (a nerve block, capsaicin, or botox) to find which works best for chronic nerve pain after breast cancer surgery. If you have ongoing pain in a small area on your chest, armpit, or arm that started 3 to 9 months after surgery, this study may help you find better relief.
Lille, Hauts-de-FranceAges 18 years+ - NCT06810336RecruitingEarly Phase 1
Pain control after brain surgery: methadone vs remifentanil
This trial compares two medicines, methadone and remifentanil, to see which one works better for pain after brain surgery. It may help improve your recovery and comfort.
Charlottesville, VirginiaAges 18–65 - NCT06811103Recruiting
How chronic pain patients make decisions about treatment
This study looks at what helps people with chronic pain make choices about their treatment. You will be asked some questions during your first pain clinic visit to see how your decision-making relates to how well treatments work.
Paris, ParisAges 18 years+ - NCT06811077Recruiting
Health coaching by a patient expert for chronic pain
This trial tests whether one-on-one coaching sessions led by a trained patient expert can help people better manage chronic pain. If you already attend a chronic pain clinic and are open to learning new coping skills, this program may support you.
Paris, FranceAges 18 years+ - NCT06816095Recruiting
Ozone therapy for pelvic pain after gynecological cancer treatment
This study is looking at whether ozone therapy can help relieve chronic pelvic pain caused by gynecological cancer treatments like radiation and chemotherapy. It aims to understand how the treatment works at a molecular level.
Las Palmas, Las PalmasAges 18 years+ - NCT06816082Recruiting
Online therapy for chronic pain rehabilitation
This trial tests if adding internet-based acceptance therapy to standard pain rehabilitation helps adults with chronic pain. It is for patients at the Linköping pain clinic who have internet access.
Linköping, Östergötland CountyAges 18 years+ - NCT06817135Recruiting
Shoulder exercises for breastfeeding neck pain
This trial tests if special shoulder-blade (scapular) exercises can help reduce neck pain in mothers who are exclusively breastfeeding. The exercises are simple and designed to strengthen the muscles that support your neck while you hold your baby.
Giza, DokkiAges 18–35 - NCT06819956RecruitingPhase 3
Lower-dose ketorolac for pain in the ICU
This trial tests whether a lower dose of the pain medicine ketorolac can safely control pain for people in the intensive care unit (ICU). If you are in the ICU and have pain, this study might help find a better way to treat it.
Edmonton, AlbertaAges 18 years+ - NCT06821516Recruiting
Comparing two nerve blocks for hip replacement pain
This study compares two different nerve block techniques to manage pain after a total hip replacement. The goal is to find out which method provides better pain relief and recovery.
Istanbul, Türki̇yeAges 18 years+ - NCT06828159Recruiting
Can wild blueberries improve joint health?
This study tests whether eating wild blueberries can improve joint health in people with arthritis. You would eat blueberries or a placebo daily for several weeks to see if they help with pain and stiffness.
Oklahoma City, OklahomaAges 40–75 - NCT06831838Recruiting
Pain management program for breast cancer survivors with joint pain
This trial tests a cognitive behavioral therapy (CBT) based program to help relieve joint and muscle pain caused by aromatase inhibitors, a common hormone therapy for breast cancer. It aims to improve your quality of life and reduce symptoms.
Jacksonville, FloridaAges 18 years+ - NCT06834724Recruiting
CPAP for sleep apnea and chronic pain
This study looks at whether CPAP treatment improves pain and daily life in people who have both sleep apnea and chronic pain. It tests if starting CPAP for the first time can help these symptoms.
BrusselsAges 18 years+ - NCT06837857RecruitingPhase 2
Opioid pain relief study for older adults with chronic pain
This study tests whether a carefully managed prescription opioid can safely help older adults with long-term pain that hasn't been relieved by other pain medicines. The goal is to see if it improves pain without harming memory or brain health.
Rochester, MinnesotaAges 65 years+ - NCT06838039Recruiting
A second nerve block for less pain after lung surgery
This study tests whether adding a second nerve block (serratus anterior block) within 24 hours after a lung surgery (VATS) can reduce pain better than the standard nerve block alone. It aims to help patients control pain with fewer strong painkillers.
HebronAges 18–70 - NCT06838572Recruiting
Cooling the wrist to reduce pain from arterial line placement
This study tests whether cooling the skin on your wrist before a routine arterial line placement (a small tube in your wrist artery) can reduce the pain of the procedure. If you are having surgery and need an arterial line, this might help make the experience more comfortable.
Chongqing, Chongqing MunicipalityAges Any age - NCT06840314Recruiting
Vibration vs traditional therapy for painful sex
This trial compares a vibrating vaginal device to standard therapy for women with pain during sex. It aims to find a more effective and comfortable treatment option.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06841276Recruiting
Digital tool for chronic pain relief study
This study tests a smartphone device called QoLibri that helps manage long-term pain. You use it at home for a few weeks to see if it reduces pain and improves daily life.
NaillouxAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.