Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,138 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07404956Recruiting
Comparing surgical and N95 masks for operating room nurses
This study checks how wearing a surgical mask or an N95 mask affects the air quality during surgery (called surgical smoke). It is for operating room nurses who work with surgical smoke regularly.
Bartın, BartınAges 18 years+ - NCT07405021Recruiting
Vagus nerve stimulation for diabetic nerve pain
This trial tests whether using a non-invasive device to stimulate the vagus nerve can reduce nerve pain and improve function in people with diabetic neuropathy. It may be a good option if you have burning or electric-shock-like foot pain despite standard diabetes care.
DamiettaAges 45–60 - NCT07401641Recruiting
Pain control study for oral cancer surgery
This study tests two different pain medicines (dezocine or nalbuphine) combined with sufentanil to see which helps better control pain after oral cancer surgery with free flap reconstruction. It also looks at side effects and how well the transplanted tissue survives.
Guangzhou, GuangdongAges 18–70 - NCT07400640Recruiting
Comparing two treatments for postherpetic neuralgia pain
This trial compares two procedures—a nerve block injection and a radiofrequency treatment—to see which works better for lasting pain after shingles. It aims to help people with persistent pain in the neck, chest, or lower back.
AnkaraAges 18–80 - NCT07405645Recruiting
Focused Ultrasound for Cancer Pain in the Head or Neck
This trial tests a non-invasive focused ultrasound treatment aimed at a specific brain area to reduce severe cancer-related pain in the head, neck, or upper chest. It may help if your pain hasn't responded to standard medications.
Boston, MassachusettsAges 18–85 - NCT07404813Enrolling by invitation
Do family voices affect brain chemistry and pain in ICU patients?
This study tests whether hearing a family member's voice can change natural brain chemicals (dopamine and serotonin) and reduce pain for people in the intensive care unit who are in a coma but can still react. It may help improve comfort during recovery.
Malatya, MalatyaAges 18–65 - NCT07401134RecruitingPhase 4
Pain relief study after vaginal surgery using witch hazel and spray
This trial tests a pain relief routine using witch hazel pads and a numbing spray after vaginal surgery. The goal is to see if using these products together helps with recovery and reduces the need for stronger pain medicine.
Miami, FloridaAges 18 years+ - NCT07402577Recruiting
Pain and opioid use in young sarcoma survivors
This study looks at pain and opioid use in adolescents and young adults who have had sarcoma. It uses a smartphone app to track symptoms over 3 months to better understand cancer-related pain.
Buffalo, New YorkAges 12–70 - NCT06668623Recruiting
Reiki for nerve pain and sleep in diabetic neuropathy
This trial tests if Reiki, a gentle hands-on energy therapy, can reduce nerve pain and improve sleep in people with diabetic neuropathy. It may offer a non-drug option for managing symptoms.
Kayseri, KocasinanAges 18–70 - NCT06778954Recruiting
Pain control gel after stomach cancer surgery
This trial tests a gel (ropivacaine in a special polymer) applied during stomach cancer surgery to reduce pain after the operation. The goal is to help patients recover with less pain and fewer side effects from painkillers.
SeoulAges 20 years+ - NCT06821217Recruiting
App-based support for endometriosis quality of life
This trial tests whether using a smartphone app can improve quality of life for people with endometriosis. You'll use the app to track symptoms and get support, and researchers will see if it helps you feel better.
BernAges 18 years+ - NCT06446830Recruiting
Vitamin B complex for pain relief after cesarean in ICU
This trial tests whether adding vitamin B complex to standard pain medicine can improve pain control after a cesarean section in critically ill women. It aims to find a safer, effective way to manage pain without relying too much on strong opioids.
Cairo, EgyptAges Any age - NCT06534710Recruiting
Electronic moxibustion for pain and healing after brain surgery
This trial tests if a special heating device (electronic moxibustion) can reduce pain and help wounds heal faster after brain surgery. It may be an option if you are recovering well three days after surgery.
Yiwu, ZhejiangAges 18–80 - NCT07393958Recruiting
Can food supplements improve quality of life with endometriosis pain?
This study tests if a food supplement (Doliral®) can help reduce pelvic pain and improve daily life in women with endometriosis. It is for those with mild to moderate endometriosis (stages I–III) who have had pain for at least three months but do not need surgery right now.
BarcelonaAges 18 years+ - NCT06830876Recruiting
Testing muscle stimulator for pain and function after leg amputation
This trial tests if a noninvasive electrical stimulator (NMES) placed on the residual leg can reduce pain and improve muscle and function in people with a below-knee amputation. It aims to offer a drug-free option for managing chronic limb pain.
Pittsburgh, PennsylvaniaAges 18–100 - NCT07390825Recruiting
Water therapy for daily living and movement in Parkinson's
This study tests if aquatic therapy (exercises in water) can improve walking, balance, posture, pain, and daily activities for people with Parkinson's. It aims to see if water-based exercise helps more than standard care.
Çankaya, AnkaraAges 40–80 - NCT07390851Recruiting
Magnesium with lidocaine for jaw and neck muscle trigger points
This trial tests whether adding magnesium to lidocaine makes trigger point injections more effective for jaw, face, or upper shoulder pain. The results will be measured by pain scales and muscle activity tests.
Giza, Giza GovernorateAges 18–70 - NCT07391306RecruitingPhase 2/Phase 3
New treatment for interstitial cystitis without Hunner's lesions
This trial is testing a new treatment for people with painful bladder syndrome (interstitial cystitis) who do not have Hunner's lesions in their bladder. It aims to see if the treatment can help reduce pelvic pain and frequent urination.
MoscowAges 18–65 - NCT07394816Recruiting
Can ultrasound-guided pain blocks reduce lung complications after abdominal surgery?
This study tests whether using ultrasound-guided pain blocks (fascial plane blocks) during major abdominal surgery can reduce lung complications after surgery, especially in older adults. It may offer better pain control and faster recovery.
Yenimahalle, AnkaraAges 65 years+ - NCT07390279Recruiting
Radiofrequency treatment for shingles-related nerve pain
This study tests a safe, non-surgical treatment called transcutaneous pulsed radiofrequency to see if it can help reduce nerve pain that continues after shingles. It targets the painful area through pads on the skin.
Istanbul, IstanbulAges 18 years+ - NCT07396246RecruitingPhase 2
Comparing two treatments for hip pain
This trial tests if a new artery-blocking procedure works better than platelet-rich plasma shots for people with chronic hip pain (greater trochanteric pain syndrome) who haven't improved with physical therapy or anti-inflammatory drugs.
GuimarãesAges 18–80 - NCT06725862Recruiting
Pain relief methods for undescended testis surgery in children
This study compares two different numbing injections (caudal block vs retrolaminar block) given before surgery to see which one provides better pain control for children aged 1-7 undergoing undescended testis surgery.
IstanbulAges 1–7 - NCT06080997Recruiting
Patient expectations before spine surgery
This study looks at what patients expect before having spinal surgery. It may help improve how doctors support you before and after the operation.
Køge, Region SjællandAges 18–100 - NCT06832046Recruiting
Intranasal fentanyl for pain in pediatric emergencies
This study looks back at children who already received fentanyl nasal spray for pain in the emergency department. It aims to see how well this method worked for treating sudden pain in children.
StrasbourgAges 1–17
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,138 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.