Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,138 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06387329RecruitingPhase 4
Antibiotic to prevent UTI after bladder Botox
This study tests whether taking a low-dose antibiotic (nitrofurantoin) before a Botox bladder injection can help prevent urinary tract infections. You may be able to join if you are getting Botox for overactive bladder or painful bladder syndrome and do not have frequent UTIs or other health issues that would make the antibiotic unsafe.
Bethesda, MarylandAges 18 years+ - NCT07383623Recruiting
Staples vs. stitches for episiotomy healing after first birth
This trial compares using surgical staples versus traditional stitches to repair an episiotomy (a cut made during childbirth) in women having their first vaginal birth. It aims to see which method causes less pain and helps the wound heal better.
Izmir, İzmirAges 18–49 - NCT07388745Recruiting
Comparing two pain blocks for heart bypass surgery
This study compares two different nerve-block injections (one near the spine, one under the shoulder blade) to see which provides better pain relief after heart bypass surgery. If you are scheduled for a planned bypass and are in reasonably good health, you might be able to join.
KütahyaAges 45–85 - NCT07388953Recruiting
Nerve block for better pain relief after colon surgery
This study tests adding a special nerve block (peripheral autonomic block) to a standard abdominal wall block to see if it provides better pain relief after minimally invasive left-sided colon surgery. It may help patients experience less pain and use fewer pain medications.
Belo Horizonte, Minas GeraisAges 18–80 - NCT07385677Recruiting
Comparing a new approach to usual care for lateral elbow pain
This trial tests if a new way of thinking about the nerves and layers in your arm (called TINLL) works better than usual therapy for people with pain on the outside of their elbow. It may help you get better faster.
South Burlington, VermontAges 18 years+ - NCT07384013Recruiting
Metamizole & blood thinners in cancer patients
This study is checking if metamizole (a common painkiller) changes how well the blood thinners apixaban or rivaroxaban work in cancer patients. It aims to help doctors safely use both medicines together for pain and blood clot prevention.
HaifaAges 18 years+ - NCT06746168Recruiting
Better pain control after knee replacement surgery
This study tests a new way to manage pain after total knee replacement. It aims to see if a specific local pain block can reduce the need for strong opioids and improve recovery.
Hasselt, LimburgAges 18–85 - NCT06836882Recruiting
Testing cavity disinfectants for deep tooth decay pain
This study tests two cavity disinfectants to see which one better reduces pain and improves healing after removing deep decay from back teeth. It is for adults with deep cavities in their lower molars that are still alive (not needing a root canal).
HaryānaAges 18 years+ - NCT06598644Recruiting
Comparing two gentle neck pain treatments
This study tests two hands-on treatments for long-lasting neck pain: a gentle gliding movement called Sustained Natural Apophyseal Glide (SNAG) and a soft-tissue release technique called Instrument Assisted Soft Tissue Mobilization (IASTM). If you have had neck pain for more than 3 months, this trial may help find which method works better for you.
Rawalpindi, Punjab ProvinceAges 20–45 - NCT07378059Recruiting
Loxoprofen patch for shingles pain
This trial tests if a loxoprofen skin patch (a non-steroidal anti-inflammatory drug) can safely relieve moderate to severe pain from shingles. It may be an option for people who have had shingles rash for less than 90 days.
BeijingAges 18 years+ - NCT07375576Recruiting
Comparing partial nerve removal to root canal for severe tooth pain
This study compares two ways to treat severe tooth pain from advanced decay: a partial nerve removal (pulpotomy) versus a full root canal treatment. It aims to find which approach works better for saving the tooth.
Hatay, AntakyaAges 18–45 - NCT07373808Recruiting
Nerve stimulation and exercise for sciatica leg pain
This study tests whether combining a mild electrical stimulation of the sciatic nerve with specific exercises can reduce leg pain from sciatica. It is for people whose nerve-related leg pain has lasted over 6 months and is at least a 3 out of 10 in intensity.
Madrid, MadridAges 18–70 - NCT07375121Recruiting
Comparing two pain pump settings for mixed surgeries
This study compares two ways of delivering pain medicine through an IV pump (called PCA) after surgery. One method gives a steady dose, and the other slowly reduces the dose. The goal is to see which works better and has fewer side effects.
BeijingAges 18–65 - NCT07372547Recruiting
Does Shower Standing Help Women Empty Bladder After Catheter Removal?
This trial compares standing in the shower versus sitting on a toilet to see which position helps women empty their bladder more completely after a urinary catheter is removed following vaginal surgery.
AshdodAges 18–99 - NCT07377357Recruiting
Electrical stimulation for chronic back-related leg pain
This trial tests if a single session of electrical stimulation to the sciatic nerve can quickly reduce leg pain related to low back problems. It may help if you have had chronic sciatica (leg pain from your back) for more than 6 months and your pain has recently been interfering with daily life.
Madrid, MadridAges 18–70 - NCT07377305Recruiting
Brain stimulation for nerve pain in NMOSD
This trial tests a new, non-invasive brain stimulation method (tTIS) to treat chronic nerve pain in people with neuromyelitis optica spectrum disorder (NMOSD). It aims to see if this treatment is safe and can reduce pain without surgery or drugs.
Xi'an, ShaanxiAges 18–75 - NCT07373210Recruiting
Placebo pills for hip surgery pain in teens and young adults
This study tests whether taking placebo pills (pills with no active drug) can help manage pain after a specific hip surgery, called Bernese Periacetabular Osteotomy (PAO), in people with a hip condition called developmental dysplasia. The goal is to see if using placebos can reduce the need for pain medications and help with recovery.
San Francisco, CaliforniaAges 13–40 - NCT07378189Recruiting
Opioid-free anesthesia for pancreatic surgery
This trial tests whether using a combination of non-opioid drugs during general anesthesia can reduce side effects after laparoscopic pancreatic surgery. If you are scheduled for this type of surgery and are between 18 and 80 years old, you may be able to join.
Krakow, Lesser Poland VoivodeshipAges 18–80 - NCT07378995Recruiting
Can play before a shot help children?
This study tests whether a fun, play-based activity given just before an antibiotic shot helps children feel less pain and fear. If your child is 4–6 years old and needs this specific shot, they may be eligible.
ErzurumAges 4–6 - NCT07378735Recruiting
Back to Life: early rehab after spinal fusion surgery
This trial tests an early rehabilitation program for people having lumbar spinal fusion surgery to see if it helps them get back to daily life faster. It may be a good option if you live in Copenhagen or Frederiksberg and have had low back pain for more than three months.
Glostrup MunicipalityAges 18 years+ - NCT07378046Recruiting
Baclofen for shingles pain: a safety and effectiveness study
This study tests whether the muscle relaxant baclofen can safely reduce shingles pain. It is for adults with moderate to severe pain who have not tried this drug before.
BeijingAges 18 years+ - NCT07370428Recruiting
Numbing injection for pain relief after lower back surgery
This study tests whether an ultrasound-guided numbing injection near the hip area can provide better pain relief after lower back surgery. If you qualify, you may receive this injection to help control pain after your operation.
BursaAges 18–65 - NCT06839716Recruiting
Comparing a numbing gel with standard pain block after stomach cancer surgery
This study tests a gel made of ropivacaine (a numbing medicine) in a special hydrogel to see if it works as well as the standard pain block injection (TAP block) for controlling pain after minimally invasive stomach cancer surgery. The gel is applied directly near the surgical wound.
SeoulAges 20 years+ - NCT07367672Recruiting
How beliefs affect pain empathy
This trial studies how our expectations can change how we feel pain for others. It may help us understand the placebo effect better.
Chengdu, SichuanAges 18–30
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,138 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.