Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,138 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06214949Recruiting
Personalized brain stimulation for chronic neck pain
This study tests if a personalized type of magnetic brain stimulation called PrTMS can help reduce chronic neck pain. It is for military health care beneficiaries who have had neck pain for at least 3 months.
Bethesda, MarylandAges 18–65 - NCT05824832RecruitingPhase 4
Buprenorphine, clonidine, and steroid to extend arm nerve block
This study tests whether adding certain medicines (buprenorphine, clonidine, and a steroid) to an arm “nerve block” during shoulder surgery can help the numbness last longer and improve comfort afterward. It is for adults having shoulder arthroscopy and compares how long the nerve block works.
Maywood, IllinoisAges 18 years+ - NCT07328295Recruiting
Does adding spine mobilization help frozen shoulder treatment?
This trial tests if adding thoracic spine mobilization to standard shoulder mobilization reduces pain and improves movement and function in people with frozen shoulder (adhesive capsulitis) at stages 2 or 3.
Islamabad, Punjab ProvinceAges 40–65 - NCT07330518Recruiting
Comparing two numbing techniques for lower tooth removal
This study compares two ways to numb the lower jaw for removing a back tooth: one blocks a small nerve near the cheek, the other blocks the main nerve trunk. The goal is to see which method works better and causes less discomfort.
Islamabad, Islamabad, PakistanAges 20–60 - NCT07327931Recruiting
Comparing two PENG block recipes for hip surgery in older adults
This study tests two different types of local numbing medicine (with and without extra additives) for a nerve block called PENG block in older adults having hip surgery. The goal is to find which method controls pain better and reduces the need for strong pain relievers.
PoznanAges 65–100 - NCT07326163Enrolling by invitation
Peppermint oil aromatherapy for fibromyalgia pain relief
This study tests whether smelling peppermint oil can help reduce pain and improve daily function in people with fibromyalgia, while also looking at cost. It uses a simple, non-invasive method (aromatherapy) to see if it can be a helpful addition to your current care.
Bilecik, BilecikAges 18 years+ - NCT07331441Recruiting
Nerve block for pain relief after major upper abdominal surgery
This trial tests a nerve block given near the ribs to see if it reduces pain after surgeries like gastric, liver, gallbladder, or pancreatic surgery. It may help you need less pain medicine after the operation.
ShanghaiAges 18–85 - NCT07325994Recruiting
Pain control during hysteroscopy for women with infertility
This trial tests if using calming words (verbal analgesia) during a hysteroscopy can reduce pain compared to standard care. It is for women with primary infertility who need this procedure to check the uterus.
GizaAges 18–40 - NCT07333417Recruiting
Rigid taping for acromioclavicular joint degeneration
This study tests whether a special rigid tape applied to the shoulder can reduce pain and improve function in people with acromioclavicular (AC) joint degeneration. The AC joint is where your collarbone meets the top of your shoulder blade, and this condition can cause pain and stiffness.
Ankara, AnkaraAges 18–65 - NCT07330063RecruitingPhase 2
Pain relief injection after laparoscopic stomach cancer surgery
This trial tests an injection called Anrikefon to see if it can safely and effectively reduce pain after surgery to remove part of the stomach for cancer. The surgery is done through small cuts (laparoscopic), and this treatment is given after surgery to help with pain while you recover.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07327138Recruiting
Laughter and yoga for kids with leukemia after chemo
This study tests if fun yoga and laughter exercises at home can help children aged 2-10 with a type of leukemia feel less pain after chemotherapy. It's designed to be gentle and safe, with a parent or guardian joining in.
SidonAges 2–10 - NCT07326774Recruiting
Ultrasound-guided pain block for back surgery recovery
This trial tests whether a special pain block (Quadro-Iliac Plane Block) given before back surgery can reduce pain after the operation. The goal is to help patients feel more comfortable and need fewer painkillers.
Istanbul, IstanbulAges 18–65 - NCT07318688RecruitingPhase 3
Testing HMI-115 for endometriosis pain
This trial tests an experimental drug called HMI-115 to see if it reduces pain from endometriosis. If you have moderate to severe period pain and non-period pain, and you have a surgical diagnosis, you may be able to join.
Beijing, Beijing MunicipalityAges 18–49 - NCT06864884RecruitingEarly Phase 1
Study of ARC-001 for wisdom teeth removal
This trial tests a new medicine called ARC-001 in people who are scheduled to have their wisdom teeth taken out. The goal is to see if it's safe and how it affects pain and healing.
Salt Lake City, UtahAges 18–55 - NCT07316166RecruitingPhase 4
Nerve Block With or Without Extra Medicine for Hip Replacement
This trial compares two types of nerve blocks for pain relief after total hip replacement. One block uses a standard numbing medicine, and the other adds a medication (dexmedetomidine) that may extend the pain relief. The goal is to see which approach works better for managing pain after surgery.
Providence, Rhode IslandAges 18–80 - NCT07315646Recruiting
Pain from IUD insertion: traditional vs. ultrasound-guided
This study tests if using ultrasound during IUD (intrauterine system) insertion reduces pain compared to the standard method. If you are getting a Kyleena or Mirena IUD, your experience may help improve comfort for other women.
GhentAges 18–60 - NCT07317271Recruiting
Virtual reality for burn symptoms
This trial tests a virtual reality program to help with symptoms like pain, trouble sleeping, and itching after a burn injury. You can join from home using your own device.
Baltimore, MarylandAges 18 years+ - NCT07317570Recruiting
Body awareness therapy for jaw pain and function
This study tests whether body awareness therapy (gentle exercises that help you notice how your body moves and feels) can reduce jaw pain, improve function, and help with related emotional stress. It is for people with long-term jaw joint problems.
RizeAges 18 years+ - NCT07324499Recruiting
Dexamethasone with nerve block for shoulder surgery
This trial tests if adding dexamethasone to a standard numbing medicine (bupivacaine) affects how much of the medicine stays in your blood. It may help improve pain relief after shoulder surgery.
SantiagoAges 18–90 - NCT07321366Recruiting
Cold therapy for muscle stiffness in cerebral palsy
This study tests a cold treatment called cryoneurolysis to reduce painful muscle tightness in the shoulder or elbow for people with cerebral palsy. It is for those who have tried other treatments like injections or medications and found they didn't work well or weren't an option.
Lyon, RhôneAges 12 years+ - NCT07318896Recruiting
Agar and collagen supplement study for knee pain
This trial tests whether a supplement made from agar and collagen can help reduce knee pain in people with mild to moderate osteoarthritis. If you are between 40 and 70 and have knee pain, this may be an option for you.
Reus, TarragonaAges 40–70 - NCT06691750Recruiting
Barbed Suture Study for Cesarean Wound Healing
This trial tests if a special type of stitch (barbed suture) used to repair the uterus during cesarean section can reduce the chance of developing a small pocket or gap in the uterine scar, called isthmocele. If you are having a planned or emergency c-section at Hospital Clinic of Barcelona, you may be able to join.
BarcelonaAges 18 years+ - NCT06444919RecruitingPhase 4
Capsaicin patch for finger osteoarthritis with nerve pain
This study tests if a capsaicin patch (a hot pepper extract) can reduce finger pain in people with osteoarthritis who also have nerve-like pain. It's for those who haven't gotten enough relief from standard painkillers.
Clermont-FerrandAges 18 years+ - NCT07311902Recruiting
Comparing two blocks for pain after hernia repair
This trial compares two types of nerve blocks (M-Tapa block and TAP block) to see which one works better for controlling pain after open inguinal hernia repair. It may help find a better way to manage pain after surgery.
ErzurumAges 18–65
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,138 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.