Clinical trials
Parkinson's Disease and Parkinsonism clinical trials
Below are recruiting parkinson's disease and parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 740 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06562569Recruiting
Non-invasive vagus nerve stimulation for Parkinson's gait issues
This study tests a non-invasive vagus nerve stimulation device to see if it can improve walking and reduce freezing of gait in people with Parkinson's disease. It is done at VA hospitals and involves wearing a device on the neck during walking tasks.
Hines, IllinoisAges 50–88 - NCT07284719Recruiting
Focused Ultrasound for Parkinson's Tremor
This trial tests a non-invasive treatment called MR-guided focused ultrasound (MRgFUS) to reduce severe tremor in Parkinson's disease. It uses sound waves to target the brain area causing the shaking, without surgery.
AarhusAges 50–80 - NCT06592014Enrolling by invitationPhase 1/Phase 2
Lithium for Parkinson's: an extension trial
This trial extends a previous study to see if lithium can help Parkinson's symptoms. It's for people who already took part in a related study at the University at Buffalo.
Williamsville, New YorkAges 45–80 - NCT04335994Recruiting
Home sleep testing for people with memory trouble
This study looks at how well home sleep apnea testing works for people with cognitive impairment (memory/thinking problems) to help improve outcomes. You may be asked to do a home sleep test (and possibly an in-lab test) and will involve a caregiver if needed.
Toronto, OntarioAges Any age - NCT04426786Recruiting
Exercise study to improve brain energy in Parkinson’s
This trial tests whether a structured exercise program can change how your brain uses energy in Parkinson’s disease. It may help improve symptoms or brain-related measures, especially in people who currently exercise very little.
Vancouver, British ColumbiaAges 40–80 - NCT04477785Recruiting
Study to track Parkinson’s signs using imaging, spinal fluid, and genes
This study is building a large, detailed group of people—some with Parkinson’s and some at higher risk—to understand early changes over time. It uses brain imaging (DaTscan SPECT), sometimes spinal fluid tests (lumbar puncture), and genetic information to help researchers better measure disease and develop future treatments.
Birmingham, AlabamaAges 30 years+ - NCT05065151Recruiting
Studying motivation in Parkinson’s using brain stimulation recordings
This study looks at what drives motivation in people with Parkinson’s disease (or dystonia) by using recordings from an implanted brain stimulation device. It may help researchers understand brain signals behind motivation and improve future treatments.
San Francisco, CaliforniaAges 18 years+ - NCT06377033Recruiting
Using health records to advance genomic medicine for all
This study uses electronic health records to learn how to improve genomic medicine across a diverse health system. It may help make DNA-based healthcare more accessible and effective for people with certain conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06416722Recruiting
Remote therapy with two tasks at once for Parkinson's
This study tests whether a remote therapy program that combines physical exercises with a thinking task can help people with Parkinson's walk better and think more clearly. It's done from home using a smartphone or computer.
Istanbul, BakırköyAges 30–75 - NCT03217396Recruiting
Study blood and MRI markers in people with multiple sclerosis
This study looks for signs of “synapse damage” in multiple sclerosis using blood tests and brain imaging (MRI). The goal is to find biomarkers that may help better understand MS and how it changes over time.
Pozzilli, IserniaAges 18–65 - NCT03402919Recruiting
Brain and memory study for people with thinking changes
This study looks at memory and thinking changes using questionnaires, memory testing, and brain scans. It may help researchers better understand neurodegeneration and dementia and how these problems show up over time.
Calgary, AlbertaAges 50–90 - NCT05826548Recruiting
Telerehabilitation program for memory, Parkinson’s, and stroke needs
This trial studies a home-based exercise and training program delivered by telerehabilitation (remote care) for people with mild cognitive impairment, Parkinson’s disease, or stroke. It may help improve day-to-day thinking and movement skills by supporting you with structured practice from home.
Lido, VeneziaAges 18–85 - NCT06949670Recruiting
Alpha-synuclein PET scan for Parkinson's disease
This trial uses a special brain scan (PET/CT) to look at a protein called alpha-synuclein in people with Parkinson's disease. The goal is to learn more about the disease and how it affects the brain.
Hefei, AnhuiAges 18–80 - NCT07697664Recruiting
Memory and thinking through exercise in aging
This study looks at whether light-to-moderate physical activity (like walking or stretching) can help memory and thinking in middle-aged and older adults. People with normal thinking, mild memory problems, or Parkinson's disease may join if they aren't already very active.
Atlanta, GeorgiaAges 18–79 - NCT07380204Recruiting
Measuring Hsp90 in the brain with a PET scan
This study uses a special PET scan to measure a protein called Hsp90 in the brain. It aims to understand how Hsp90 levels differ in healthy people and those with Parkinson's, Alzheimer's, or ALS, which may lead to new treatments.
Leuven, Vlaam-BrabantAges 18–70 - NCT07213232Enrolling by invitation
Balance and thinking training for Parkinson's
This study tests if combining balance and walking exercises with thinking tasks can improve movement and daily life in people with Parkinson's disease. It is for those in early to moderate stages who can participate in physical and cognitive training.
Ankara, ÜniversitelerAges 40 years+ - NCT07056348Recruiting
Brain stimulation to improve movement in Parkinson's or tremor
This study tests brain stimulation in a region called VOP/VIM to see if it can improve motor function. It is for people with movement disorders who are already getting deep brain stimulation (DBS) surgery.
Pittsburgh, PennsylvaniaAges 18–80 - NCT04114994Recruiting
Memory testing study for adults 50 and older
This study checks how people’s thinking and memory change over time using a specific cognitive test. It may help researchers understand patterns of memory change and supports future research on brain health.
Miami, FloridaAges 50 years+ - NCT06291051Recruiting
Spinal cord stimulation for Parkinson's with painful bent spine
This study tests whether a spinal cord stimulator (a device that sends mild electrical pulses to the back) is safe and can reduce pain and improve the forward-bent posture in people with Parkinson's disease. It is for those whose bent posture has not improved with standard medication and is causing significant pain.
AmiensAges 18 years+ - NCT07082595Recruiting
Personalized brain stimulation to improve walking in Parkinson's
This study tests a personalized brain stimulation system to help improve walking and balance in people with Parkinson's. If you have trouble with gait and posture despite treatment, this trial may explore whether a tailored stimulation loop can offer additional benefit.
Zurich, Canton of ZurichAges 18 years+ - NCT07595666Enrolling by invitation
New PET scanner versus standard PET for head and neck imaging
This study compares a newer PET/CT scanner (called NeuroEXPLORER) with standard PET/CT scanners for imaging the head and neck region. The goal is to see if the new scanner provides better or clearer images to help diagnose conditions.
Leuven, Vlaams-BrabantAges 4 weeks+ - NCT06980935Enrolling by invitation
Brain stimulation for Parkinson's motor symptoms
This study tests a new type of brain stimulation (STN-tTIS) to see if it helps improve movement symptoms in people with Parkinson's. The study compares how the stimulation works when you are taking your regular medications and when you are not.
Shanghai, Shanghai MunicipalityAges 50–85 - NCT04844060Recruiting
Study collecting spinal fluid from patients needing a lumbar puncture
This study collects cerebrospinal fluid (the fluid around the brain and spinal cord) during a lumbar puncture. It aims to improve how doctors use this information for accurate diagnosis in patients who need the procedure.
StrasbourgAges Any age - NCT01558479Recruiting
Parkinson’s genetics study for adults in affected families
This study looks at genetic (inherited) factors in Parkinson’s disease. It may help researchers better understand why Parkinson’s happens and could guide future prevention or treatments.
Atlanta, GeorgiaAges 18 years+
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Common questions
- Are there clinical trials for parkinson's disease and parkinsonism?
- Yes. Clin2 currently lists 740 recruiting parkinson's disease and parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson's disease and parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson's disease and parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.