Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 723 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04715984Recruiting
Testing brain-circuit targets during DBS surgery in Parkinson’s
This study looks at how brain connections involved in movement may relate to thinking and memory problems in Parkinson’s disease. It happens during a deep brain stimulation (DBS) operation, using tests while the surgeon is placing an electrode.
Nashville, TennesseeAges 40 years+ - NCT06439355Recruiting
Taste test for Parkinson's and Lewy body disease
This study measures how well people with Parkinson's or Lewy body disease can taste, using a special test. It aims to understand if taste problems are linked to these conditions and could help with earlier diagnosis.
DijonAges 18 years+ - NCT06745011Enrolling by invitation
Parkinson's signs in people with nerve damage
This study looks for early signs of Parkinson's disease in people who have nerve damage in their hands and feet (polyneuropathy) with no known cause, along with drops in blood pressure when standing up. It aims to understand if these early symptoms might predict future Parkinson's.
Aarhus, JutlandAges 18–85 - NCT07308795Recruiting
Measuring belly breathing muscles in Parkinson’s patients
This trial uses ultrasound to measure the size of belly and rib muscles that help you breathe. It looks at how these muscles relate to the severity of Parkinson’s and your ability to exhale strongly.
Istanbul, BAHÇELİEVLERAges 18–75 - NCT07790744Recruiting
Brain imaging study for early Parkinson's signs in people with REM sleep disorder
This study uses MRI scans to look at the brain in people with REM sleep behavior disorder (RBD), a condition that can be an early sign of Parkinson's disease. By comparing them with healthy volunteers, researchers hope to find early markers of Parkinson's that could lead to earlier diagnosis and treatment.
HvidovreAges 18 years+ - NCT06733077Recruiting
Digital services for Parkinson's disease
This study is developing digital services for people with Parkinson's disease and also includes healthy volunteers. It aims to understand movement problems like freezing of gait and festination, and uses a virtual reality system to measure these issues.
ExeterAges 18 years+ - NCT07213219Recruiting
PET-MRI scan for Parkinson's with sleep behavior disorder
This trial uses a combined PET and MRI scan to study the brain's reward system in people with Parkinson's disease who also have REM sleep behavior disorder (RBD). It aims to understand how the brain changes and may help guide future treatments.
Clermont-FerrandAges 45–80 - NCT07142044RecruitingPhase 1/Phase 2
Testing EC5026 for Parkinson's disease
This study tests a new oral medication called EC5026 for Parkinson's disease. It aims to see if the drug is safe and if it might help control symptoms when added to your current levodopa treatment.
Sacramento, CaliforniaAges 50–80 - NCT06920134Recruiting
Spinal cord stimulation for blood pressure in Parkinson's disease
This trial tests if electrical stimulation of the spinal cord can help manage blood pressure drops (orthostatic hypotension) in people with Parkinson's and related conditions. It might make daily activities like standing and walking easier.
Lausanne, Canton of VaudAges 18–90 - NCT06899022Recruiting
Attention and eye movement in Parkinson's disease
This study looks at how attention and eye movements work in people with Parkinson's disease, essential tremor, or dystonia. It tests abilities during deep brain stimulation (DBS) surgery and when DBS settings are changed.
Omaha, NebraskaAges 19–90 - NCT05070013Recruiting
Brain stimulation to improve sleep in people with Parkinson’s disease
This study tests an adaptive brain stimulation device to help restore better sleep in people with Parkinson’s disease. You may be eligible if your Parkinson’s motor symptoms are severe despite best medical treatment and you are already being considered for a specific deep brain stimulation surgery.
Omaha, NebraskaAges 18–80 - NCT05769699Recruiting
Blood test study for Parkinson’s stages
This study measures blood biomarkers (measurable substances in blood) in people with Parkinson’s at different stages. It may help doctors understand how Parkinson’s changes over time and could guide future testing or treatments.
RomaAges 18–80 - NCT06090682Recruiting
Brain stimulation for Parkinson's with thinking problems
This trial tests a brain stimulation technique (deep brain stimulation) to see if it can help people with Parkinson's disease who also have mild cognitive problems. The goal is to understand how stimulation affects both movement and thinking.
Tianjin, Tianjin MunicipalityAges Up to 75 years - NCT04087031Recruiting
Tech-based rehab for early Parkinson’s symptoms in older adults
This trial tests an innovative, technology-supported rehabilitation program to help older adults with early-stage Parkinson’s disease improve daily function. It may be helpful if your symptoms are mild and your treatments have been stable for at least a month.
AnconaAges 65 years+ - NCT06316232RecruitingPhase 4
DBS and Levodopa for Freezing of Gait in Parkinson's
This trial tests whether increasing the dose of levodopa or adjusting deep brain stimulation (DBS) can help reduce freezing of gait in people with Parkinson's who already have good control of other symptoms. It aims to find the best way to manage this common and frustrating problem.
BolognaAges 18–80 - NCT07833748Recruiting
Combined thinking and movement training for Parkinson's disease
This study tests a program that combines cognitive (thinking) exercises with physical (movement) training for people with Parkinson's disease. The goal is to see if this combined approach is feasible and beneficial for improving both mental and motor symptoms.
Ferrara, FEAges 18 years+ - NCT07787299Recruiting
Wearable sensors for monitoring tremor in Parkinson's disease
This study tests whether wearable sensors can accurately measure tremor and other movement symptoms in people with Parkinson's disease or essential tremor. Participating may help improve how doctors monitor symptoms at home.
Edinburgh, EdinburghAges 18 years+ - NCT06548256Recruiting
Probiotic for Parkinson's Symptoms
This trial tests whether a probiotic called Clostridium butyricum can help with both movement and non-movement symptoms of Parkinson's disease. It aims to see if improving gut health can ease symptoms.
Kaohsiung CityAges 20–90 - NCT06570421Recruiting
Nerve stimulation for Parkinson's and essential tremor
This study tests a non-invasive nerve stimulation device for reducing tremors in people with Parkinson's disease or essential tremor. It follows up participants from a previous trial to see if benefits last up to 24 months.
OstravaAges 18 years+ - NCT07679256Recruiting
Digital and brain markers for early Parkinson's diagnosis
This study uses digital tools and brain markers to detect Parkinson's disease early. It includes healthy people, those with early Parkinson's, and those with REM sleep behavior disorder (a possible early sign).
Fuzhou, FujianAges 40–80 - NCT07376278Recruiting
Deep brain stimulation outcomes in Parkinson's disease
This study looks at factors that predict how well deep brain stimulation (DBS) works for people with Parkinson's disease. If you are considering DBS, joining this research could help doctors better understand who benefits most from the procedure.
Hong KongAges 18–75 - NCT07156773RecruitingPhase 2
Nasal spray for Parkinson's off episodes
This study tests a new nasal spray called XJN010 for people with Parkinson's who have 'off' episodes—times when their regular medication wears off and symptoms come back. The goal is to see if the spray can safely and effectively help during those periods.
Guangzhou, GuangdongAges 30–85 - NCT07097298Recruiting
Empathy and compassion study for Parkinson's patients and caregivers
This study explores empathy and self-compassion in people with Parkinson's disease and their caregivers. If you have mild to moderate Parkinson's and a caregiver at home, you and your caregiver may join together to help researchers understand how to better support both of you.
LuganoAges 50–80 - NCT06909045Recruiting
Adaptive vs. regular deep brain stimulation for Parkinson's
This study compares two ways of using deep brain stimulation (DBS) — an adjustable ‘adaptive’ version that changes with your brain signals, versus the standard continuous setting. It aims to see which works better for people with Parkinson's disease who already have a specific type of DBS device.
LeuvenAges 18 years+
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 723 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.