Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 740 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04715984Recruiting
Testing brain-circuit targets during DBS surgery in Parkinson’s
This study looks at how brain connections involved in movement may relate to thinking and memory problems in Parkinson’s disease. It happens during a deep brain stimulation (DBS) operation, using tests while the surgeon is placing an electrode.
Nashville, TennesseeAges 40 years+ - NCT06390761Recruiting
Acupuncture for constipation in Parkinson's disease
This trial tests whether acupuncture can help relieve constipation in people with Parkinson's disease. If you have both Parkinson's and constipation that is not caused by another medical condition, this study may offer a non-drug treatment option.
Xi'an, ShaanxiAges 35–80 - NCT06487364Recruiting
How much change in a Parkinson's quality-of-life test matters
This study looks at a short questionnaire (Parkinson's Disease Questionnaire-8) that measures how Parkinson's affects your daily life. The goal is to find out the smallest change in the questionnaire that really matters to patients.
IstanbulAges 40–80 - NCT06528964Recruiting
Skin protein study for Alzheimer's, Parkinson's, and related disorders
This study looks at the skin of people with memory or movement disorders (like Alzheimer's, Parkinson's, ALS) to find proteins that may help diagnose these conditions. If you have one of these diseases or are a healthy older adult, you may be able to join by giving a small skin sample.
San Luis Potosí CityAges 45 years+ - NCT06598891Recruiting
Balance training for Parkinson's disease
This study tests a special balance training program for people with Parkinson's disease. It aims to see if it can improve walking and reduce falls.
TaoyuanAges 20 years+ - NCT06772220Recruiting
Homocysteine management for Parkinson's patients on levodopa
This trial tests whether controlling homocysteine levels can help people with Parkinson's disease who are taking levodopa. You may qualify if you take at least 300 mg of levodopa per day, are between 40 and 90 years old, and have no major kidney problems or uncontrolled high blood pressure.
Portland, OregonAges 40–90 - NCT07058285Recruiting
Exercise program for better walking in Parkinson's
This trial tests whether a structured exercise program can help people with Parkinson's disease walk better and feel steadier. If you are in the early-to-moderate stages and have some walking issues, you may be able to join.
KielAges Any age - NCT07182058RecruitingPhase 1/Phase 2
Brain stimulation device for Parkinson's motor symptoms
This trial tests a wearable brain stimulation device (tES) that delivers gentle electrical currents to your head to help improve Parkinson's motor symptoms like tremor, stiffness, or slowness. The treatment is done at home with remote video monitoring, and may offer a non-medication option to help with movement.
Cleveland, OhioAges 18–80 - NCT07246278RecruitingPhase 1/Phase 2
Celecoxib for Parkinson's: A new way to treat symptoms
This trial tests if adding celecoxib, an anti-inflammatory drug, to standard Parkinson's treatment can help improve symptoms. If you have Parkinson's disease and are at least 18, this study might be an option for you.
TantaAges 50–80 - NCT07316296RecruitingPhase 3
Testing a drug to reduce freezing of gait in Parkinson's
This trial tests whether atomoxetine, a drug that boosts a brain chemical called noradrenaline, can help reduce freezing of gait—a feeling of your feet being stuck to the ground—in people with Parkinson's disease. You would continue your usual Parkinson's medications during the study and undergo walking tests and brain scans to see if the drug helps.
Nijmegen, GelderlandAges 18 years+ - NCT07461220RecruitingPhase 1/Phase 2
Testing IRL757 for apathy in Parkinson's disease
This trial tests a new drug called IRL757 to see if it is safe and helps with apathy (loss of motivation or interest) in people with Parkinson's disease. You need to have at least moderate apathy and a caregiver who can come to visits with you.
PlevenAges 50–90 - NCT06439355Recruiting
Taste test for Parkinson's and Lewy body disease
This study measures how well people with Parkinson's or Lewy body disease can taste, using a special test. It aims to understand if taste problems are linked to these conditions and could help with earlier diagnosis.
DijonAges 18 years+ - NCT06745011Enrolling by invitation
Parkinson's signs in people with nerve damage
This study looks for early signs of Parkinson's disease in people who have nerve damage in their hands and feet (polyneuropathy) with no known cause, along with drops in blood pressure when standing up. It aims to understand if these early symptoms might predict future Parkinson's.
Aarhus, JutlandAges 18–85 - NCT07308795Recruiting
Measuring belly breathing muscles in Parkinson’s patients
This trial uses ultrasound to measure the size of belly and rib muscles that help you breathe. It looks at how these muscles relate to the severity of Parkinson’s and your ability to exhale strongly.
Istanbul, BAHÇELİEVLERAges 18–75 - NCT07790744Recruiting
Brain imaging study for early Parkinson's signs in people with REM sleep disorder
This study uses MRI scans to look at the brain in people with REM sleep behavior disorder (RBD), a condition that can be an early sign of Parkinson's disease. By comparing them with healthy volunteers, researchers hope to find early markers of Parkinson's that could lead to earlier diagnosis and treatment.
HvidovreAges 18 years+ - NCT07142044RecruitingPhase 1/Phase 2
Testing EC5026 for Parkinson's disease
This study tests a new oral medication called EC5026 for Parkinson's disease. It aims to see if the drug is safe and if it might help control symptoms when added to your current levodopa treatment.
Sacramento, CaliforniaAges 50–80 - NCT05070013Recruiting
Brain stimulation to improve sleep in people with Parkinson’s disease
This study tests an adaptive brain stimulation device to help restore better sleep in people with Parkinson’s disease. You may be eligible if your Parkinson’s motor symptoms are severe despite best medical treatment and you are already being considered for a specific deep brain stimulation surgery.
Omaha, NebraskaAges 18–80 - NCT07213219Recruiting
PET-MRI scan for Parkinson's with sleep behavior disorder
This trial uses a combined PET and MRI scan to study the brain's reward system in people with Parkinson's disease who also have REM sleep behavior disorder (RBD). It aims to understand how the brain changes and may help guide future treatments.
Clermont-FerrandAges 45–80 - NCT06733077Recruiting
Digital services for Parkinson's disease
This study is developing digital services for people with Parkinson's disease and also includes healthy volunteers. It aims to understand movement problems like freezing of gait and festination, and uses a virtual reality system to measure these issues.
ExeterAges 18 years+ - NCT06899022Recruiting
Attention and eye movement in Parkinson's disease
This study looks at how attention and eye movements work in people with Parkinson's disease, essential tremor, or dystonia. It tests abilities during deep brain stimulation (DBS) surgery and when DBS settings are changed.
Omaha, NebraskaAges 19–90 - NCT06920134Recruiting
Spinal cord stimulation for blood pressure in Parkinson's disease
This trial tests if electrical stimulation of the spinal cord can help manage blood pressure drops (orthostatic hypotension) in people with Parkinson's and related conditions. It might make daily activities like standing and walking easier.
Lausanne, Canton of VaudAges 18–90 - NCT04087031Recruiting
Tech-based rehab for early Parkinson’s symptoms in older adults
This trial tests an innovative, technology-supported rehabilitation program to help older adults with early-stage Parkinson’s disease improve daily function. It may be helpful if your symptoms are mild and your treatments have been stable for at least a month.
AnconaAges 65 years+ - NCT05658302Recruiting
Deep brain stimulation for Parkinson’s, using targeted stimulation
This study is testing a specific approach to deep brain stimulation (DBS) for people with Parkinson’s disease who are getting DBS surgery as part of routine care. It may help doctors learn whether circuit-based, more targeted stimulation is safe and useful for Parkinson’s symptoms.
Minneapolis, MinnesotaAges 21 years+ - NCT05769699Recruiting
Blood test study for Parkinson’s stages
This study measures blood biomarkers (measurable substances in blood) in people with Parkinson’s at different stages. It may help doctors understand how Parkinson’s changes over time and could guide future testing or treatments.
RomaAges 18–80
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 740 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.