Clinical trials
Patient clinical trials
Below are recruiting patient clinical trials, each written for real people, not researchers. We’re tracking 14,861 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05445791RecruitingPhase 3
Metformin plus targeted lung cancer drugs for EGFR-mutated cancer
This Phase 3 study tests whether adding metformin to standard targeted medicines (tyrosine kinase inhibitors) helps people with EGFR-mutated non-small cell lung cancer. It’s meant for people who haven’t already had EGFR-targeted treatment and who have healthy enough labs and organs to safely take the study medicines.
Mexico CityAges 18 years+ - NCT05445960Recruiting
Tourniquet use during ankle surgery and recovery outcomes
This study looks at whether using a tourniquet during ankle fracture surgery affects healing, leg movement, and patient-reported recovery. It may help doctors choose the safest, most comfortable approach for surgery.
Portland, OregonAges 18–89 - NCT05447338Recruiting
Manual therapy for neck pain with limited neck motion
This trial tests whether hands-on/manual physical therapy helps people with neck pain and reduced neck movement. It may help improve motion and reduce symptoms if your neck pain fits the trial’s type and severity.
CórdobaAges 25–50 - NCT05447923Recruiting
Colorectal screening study for Black and underserved Phoenix adults
This study aims to help improve colorectal cancer screening (checking the colon) in Black and underserved communities in Phoenix. It may help you find out which screening tests fit you and encourage regular screening.
Scottsdale, ArizonaAges 45 years+ - NCT05448833Recruiting
Testing a wireless sensor to monitor left heart pressure
This study tests whether a small wireless sensor can safely measure and track pressure in the left upper heart chamber in people with advanced chronic heart failure. It may help the care team better understand pressure changes that are linked to fluid buildup and symptoms, alongside your usual heart medicines.
Petah TikvaAges 22–88 - NCT05449522Recruiting
Vitamin D after major trauma in ICU patients
This trial tests whether giving vitamin D to adults in the ICU after major trauma can improve outcomes. It’s meant for people who don’t have certain conditions that raise calcium levels or make feeding with the study plan unsafe.
TaipeiAges 20 years+ - NCT05450185Recruiting
Test filter lifespan during continuous kidney dialysis
This study looks at whether the lifespan (how long they can be used) of dialysis filters can be optimized during continuous kidney dialysis for very sick adults. If successful, it may improve care and use of dialysis supplies for people with dialysis-dependent kidney injury.
InnsbruckAges 18 years+ - NCT05450432RecruitingPhase 4
Ketamine maintenance to help prevent suicidal thoughts
This Phase 4 study tests whether ongoing treatment with ketamine or esketamine can reduce suicidal thoughts in people with major depression who are at high risk. Because the study focuses on long-term maintenance, you’d receive treatment over time while being closely monitored for safety and mental health changes.
Boston, MassachusettsAges 18–70 - NCT05452889RecruitingEarly Phase 1
PET scan study in pulmonary hypertension related to scleroderma
This early study uses a PET scan (a type of imaging test) to better understand lung blood-vessel disease in people who have pulmonary hypertension related to scleroderma. It may help researchers find how imaging signals relate to disease and risk.
Pittsburgh, PennsylvaniaAges 18–75 - NCT05452213RecruitingPhase 4
Study patterns of ribociclib response and resistance in breast cancer
This trial looks at how well ribociclib works and why it may stop working over time in people with advanced, hormone-receptor–positive, HER2-negative breast cancer. It also analyzes blood and tissue samples to help researchers understand resistance patterns and improve future treatment decisions.
Erlangen, BavariaAges 18 years+ - NCT05454280RecruitingPhase 3
Manage surgical risk after high-risk cancer operations
This study looks at a “risk-based plan” to help guide care after major cancer surgery, aiming to improve recovery and outcomes. You may be in the study when you’re about to have elective (planned) high-risk cancer surgery and then again just before hospital discharge.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05454527Recruiting
Biobank study follow-up for adults with inflammatory muscle disease
This study follows adults who have (or are being evaluated for) inflammatory muscle conditions to collect health data and genetic test information. It may help researchers better understand these diseases and improve future care.
ParisAges 18 years+ - NCT05455619RecruitingPhase 1/Phase 2
Targeted drugs for PI3K-altered, HR+/HER2- breast cancer
This Phase 1/2 trial tests how well a combination of targeted medicines works for advanced or returning HR+/HER2- breast cancer that has a PI3K pathway change (such as PIK3CA, PTEN, or AKT1). It may help by blocking growth signals in the cancer and is especially for people whose cancer has progressed after hormone therapy and a CDK4/6 inhibitor.
Loma Linda, CaliforniaAges 18 years+ - NCT05456893Recruiting
Testing blood and stool markers in active ulcerative colitis treatments
This study checks biomarkers (signals in blood and/or stool) in adults with moderate-to-severe ulcerative colitis. It compares patients starting targeted medicines and looks for marker patterns that may reflect how the disease is behaving.
Nancy, LorraineAges 18 years+ - NCT05457738Recruiting
Home walking program using a smartphone app for leg artery pain
This trial tests whether a home-based walking (exercise) plan, guided by a new smartphone app, can help people with intermittent claudication caused by blocked leg arteries. It may help improve walking comfort and ability by using a structured, app-supported exercise routine.
ReimsAges 18 years+ - NCT05458947Recruiting
Physical therapy wound treatments for spinal cord injury sores
This study tests different physical therapy approaches to help heal pressure sores on the sacrum or ischium in people with a spinal cord injury. You may be able to join if you’re already in inpatient rehabilitation and your wound severity score fits the study criteria.
Charlotte, North CarolinaAges 18 years+ - NCT05459597Recruiting
Testing seizure medicine in older adults
This trial studies how seizure (epilepsy) medicines work in people age 65 and older. If you have epilepsy and are already taking seizure medication, you may be able to join to help researchers learn what to expect from these treatments in older adults.
Jinan, ShandongAges 65–100 - NCT05460507RecruitingPhase 1
Re-treating brain tumor with radioactive liposome after prior dose
This Phase 1 trial tests whether a radioactive treatment delivered in tiny fat “packets” is safe and tolerable when given again to people whose glioma (brain tumor) came back after a previous similar treatment. It also looks at how well this re-treatment works in carefully selected patients.
San Antonio, TexasAges 18 years+ - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT05463380Recruiting
Study of hospitalized adults with COVID-19
This study follows adults who are in the hospital (including the emergency ward) with a confirmed COVID-19 infection. It aims to learn how COVID-19 affects people in the hospital and how different cases may differ over time.
DüsseldorfAges 18 years+ - NCT05464719RecruitingPhase 2
Loncastuximab for lymphoma patients in partial remission after CAR T
This trial studies loncastuximab tesirine (a targeted cancer medicine) given after CAR T-cell therapy when your lymphoma has improved to a partial remission. It aims to reduce the chance of the lymphoma returning after CAR T.
Houston, TexasAges 18 years+ - NCT05465200Recruiting
Study for cardiogenic shock treatment in adults under 24 hours
This trial is testing a treatment approach for adults with cardiogenic shock, a life-threatening condition where the heart can’t pump enough blood. You may be considered if your shock started within the last 24 hours and you meet other safety criteria.
WroclawAges 18–60 - NCT05466565Recruiting
Peginterferon antiviral treatment after liver cancer surgery
This trial studies an antiviral medicine given after surgery for liver cancer to help prevent the cancer from coming back. It focuses on people who are hepatitis B–positive (HBsAg positive) and have complete remission on follow-up checks.
Changsha, HunanAges 18–65 - NCT05467189Recruiting
Testing anti-cancer drugs in people age 65 and older
This study looks at how anti-cancer (chemotherapy) drugs are used in adults age 65+ who have cancer. It may help doctors understand which treatments work best and are safest for older adults.
Jinan, ShandongAges 65–100
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Common questions
- Are there clinical trials for patient?
- Yes. Clin2 currently lists 14,861 recruiting patient studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a patient trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a patient trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.